Iovance Biotherapeutics, Inc. IOVA
Set alert
At close · Oct 30
After hours · Oct 30, 7:59 PM ET
- YTD
- +210.62%
- 1 year
- +334.87%
- Open
- 9.15
- Prev close
- 9.56
- Mkt cap
- 3.84B
- Vol
- 31.20M
- Avg vol
- 17.06M
- EPS
- -0.69
- P/E
- 0.00
- Div yield
- 0.00%
More statistics
- Low
- 8.27
- High
- 9.17
- Forward P/E
- -43.32
- Beta
- 0.76
- Short ratio
- 3.26
- Inst. own
- 70.71%
- Dividend
- 0.00
- Ex-div date
- Earnings
- Nov 5, 2026
- 50-d avg
- 11.38
- 200-d avg
- 5.81
- 1y target
- 14.40
5D chart
Signals (138)
| Name | Time | Ago |
|---|---|---|
| MACD: Buy Signal | Oct 30, 3:55 PM | 1 day ago |
| MACD: Sell Signal | Oct 30, 2:45 PM | 1 day ago |
| SMA: Bearish | Oct 30, 2:40 PM | 1 day ago |
| SMA: Bearish | Oct 30, 2:40 PM | 1 day ago |
| SMA: Bullish | Oct 30, 2:25 PM | 1 day ago |
| SMA: Bullish | Oct 30, 2:25 PM | 1 day ago |
| MACD: Buy Signal | Oct 30, 2:25 PM | 1 day ago |
| MACD: Sell Signal | Oct 30, 2:20 PM | 1 day ago |
| SMA: Bearish | Oct 30, 2:10 PM | 1 day ago |
| SMA: Bearish | Oct 30, 2:10 PM | 1 day ago |
| SMA: Bullish | Oct 30, 1:35 PM | 1 day ago |
| SMA: Bullish | Oct 30, 1:35 PM | 1 day ago |
| SMA: Bearish | Oct 30, 1:30 PM | 1 day ago |
| SMA: Bullish | Oct 30, 1:15 PM | 1 day ago |
| SMA: Bearish | Oct 30, 12:35 PM | 1 day ago |
| SMA: Bullish | Oct 30, 12:20 PM | 1 day ago |
| MACD: Buy Signal | Oct 30, 12:20 PM | 1 day ago |
| MACD: Sell Signal | Oct 30, 12:00 PM | 1 day ago |
| SMA: Bearish | Oct 30, 11:15 AM | 1 day ago |
| MACD: Buy Signal | Oct 30, 10:35 AM | 1 day ago |
| SMA: Bullish | Oct 30, 10:25 AM | 1 day ago |
| RSI: Oversold | Oct 30, 9:30 AM | 1 day ago |
| SMA: Bearish | Oct 29, 3:55 PM | 2 days ago |
| SMA: Bearish | Oct 29, 3:55 PM | 2 days ago |
| MACD: Sell Signal | Oct 29, 3:55 PM | 2 days ago |
| SMA: Bullish | Oct 29, 3:50 PM | 2 days ago |
| SMA: Bullish | Oct 29, 3:50 PM | 2 days ago |
| MACD: Buy Signal | Oct 29, 3:50 PM | 2 days ago |
| SMA: Bearish | Oct 29, 3:45 PM | 2 days ago |
| MACD: Sell Signal | Oct 29, 3:35 PM | 2 days ago |
| SMA: Bearish | Oct 29, 3:30 PM | 2 days ago |
| SMA: Bullish | Oct 29, 3:25 PM | 2 days ago |
| SMA: Bearish | Oct 29, 3:05 PM | 2 days ago |
| SMA: Bearish | Oct 29, 2:20 PM | 2 days ago |
| SMA: Bullish | Oct 29, 1:45 PM | 2 days ago |
| SMA: Bullish | Oct 29, 1:45 PM | 2 days ago |
| SMA: Bearish | Oct 29, 1:40 PM | 2 days ago |
| SMA: Bearish | Oct 29, 1:40 PM | 2 days ago |
| SMA: Bullish | Oct 29, 1:35 PM | 2 days ago |
| SMA: Bullish | Oct 29, 1:35 PM | 2 days ago |
| RSI: Oversold | Oct 29, 1:15 PM | 2 days ago |
| SMA: Bearish | Oct 29, 1:10 PM | 2 days ago |
| SMA: Bullish | Oct 29, 12:50 PM | 2 days ago |
| SMA: Bearish | Oct 29, 12:30 PM | 2 days ago |
| SMA: Bullish | Oct 29, 12:25 PM | 2 days ago |
| MACD: Buy Signal | Oct 29, 10:45 AM | 2 days ago |
| SMA: Bearish | Oct 29, 9:30 AM | 2 days ago |
| SMA: Bearish | Oct 29, 9:30 AM | 2 days ago |
| MACD: Sell Signal | Oct 29, 9:30 AM | 2 days ago |
| RSI: Oversold | Oct 29, 9:30 AM | 2 days ago |
| SMA: Bullish | Oct 28, 3:50 PM | 3 days ago |
| SMA: Bullish | Oct 28, 3:50 PM | 3 days ago |
| MACD: Buy Signal | Oct 28, 3:50 PM | 3 days ago |
| MACD: Sell Signal | Oct 28, 3:45 PM | 3 days ago |
| SMA: Bearish | Oct 28, 3:40 PM | 3 days ago |
| SMA: Bearish | Oct 28, 3:40 PM | 3 days ago |
| MACD: Buy Signal | Oct 28, 3:30 PM | 3 days ago |
| SMA: Bullish | Oct 28, 3:25 PM | 3 days ago |
| SMA: Bullish | Oct 28, 3:25 PM | 3 days ago |
| MACD: Sell Signal | Oct 28, 3:05 PM | 3 days ago |
| SMA: Bearish | Oct 28, 3:00 PM | 3 days ago |
| SMA: Bullish | Oct 28, 2:55 PM | 3 days ago |
| SMA: Bullish | Oct 28, 2:55 PM | 3 days ago |
| SMA: Bearish | Oct 28, 2:50 PM | 3 days ago |
| SMA: Bearish | Oct 28, 2:50 PM | 3 days ago |
| SMA: Bullish | Oct 28, 2:25 PM | 3 days ago |
| SMA: Bearish | Oct 28, 2:20 PM | 3 days ago |
| SMA: Bullish | Oct 28, 2:10 PM | 3 days ago |
| SMA: Bearish | Oct 28, 2:05 PM | 3 days ago |
| SMA: Bullish | Oct 28, 2:00 PM | 3 days ago |
| MACD: Buy Signal | Oct 28, 2:00 PM | 3 days ago |
| SMA: Bearish | Oct 28, 1:35 PM | 3 days ago |
| MACD: Sell Signal | Oct 28, 1:35 PM | 3 days ago |
| MACD: Buy Signal | Oct 28, 1:30 PM | 3 days ago |
| SMA: Bullish | Oct 28, 1:20 PM | 3 days ago |
| SMA: Bearish | Oct 28, 1:15 PM | 3 days ago |
| SMA: Bullish | Oct 28, 1:10 PM | 3 days ago |
| SMA: Bearish | Oct 28, 12:35 PM | 3 days ago |
| SMA: Bearish | Oct 28, 12:35 PM | 3 days ago |
| SMA: Bullish | Oct 28, 12:30 PM | 3 days ago |
| SMA: Bearish | Oct 28, 12:20 PM | 3 days ago |
| MACD: Sell Signal | Oct 28, 11:50 AM | 3 days ago |
| SMA: Bearish | Oct 28, 11:40 AM | 3 days ago |
| MACD: Buy Signal | Oct 28, 10:45 AM | 3 days ago |
| SMA: Bullish | Oct 28, 10:40 AM | 3 days ago |
| SMA: Bullish | Oct 28, 10:40 AM | 3 days ago |
| MACD: Sell Signal | Oct 28, 10:25 AM | 3 days ago |
| SMA: Bearish | Oct 28, 10:20 AM | 3 days ago |
| SMA: Bullish | Oct 28, 10:10 AM | 3 days ago |
| SMA: Bullish | Oct 28, 10:10 AM | 3 days ago |
| MACD: Buy Signal | Oct 28, 10:10 AM | 3 days ago |
| MACD: Sell Signal | Oct 28, 10:05 AM | 3 days ago |
| SMA: Bearish | Oct 28, 10:00 AM | 3 days ago |
| MACD: Buy Signal | Oct 28, 9:40 AM | 3 days ago |
| SMA: Bullish | Oct 28, 9:35 AM | 3 days ago |
| SMA: Bearish | Oct 27, 3:45 PM | 4 days ago |
| SMA: Bearish | Oct 27, 3:45 PM | 4 days ago |
| SMA: Bullish | Oct 27, 3:35 PM | 4 days ago |
| SMA: Bullish | Oct 27, 3:35 PM | 4 days ago |
| SMA: Bearish | Oct 27, 3:15 PM | 4 days ago |
| MACD: Sell Signal | Oct 27, 3:15 PM | 4 days ago |
| SMA: Bearish | Oct 27, 3:10 PM | 4 days ago |
| MACD: Buy Signal | Oct 27, 2:40 PM | 4 days ago |
| SMA: Bullish | Oct 27, 2:25 PM | 4 days ago |
| SMA: Bearish | Oct 27, 1:45 PM | 4 days ago |
| SMA: Bullish | Oct 27, 1:20 PM | 4 days ago |
| SMA: Bullish | Oct 27, 1:20 PM | 4 days ago |
| SMA: Bearish | Oct 27, 1:10 PM | 4 days ago |
| SMA: Bullish | Oct 27, 1:05 PM | 4 days ago |
| SMA: Bullish | Oct 27, 1:00 PM | 4 days ago |
| SMA: Bearish | Oct 27, 12:55 PM | 4 days ago |
| SMA: Bearish | Oct 27, 12:15 PM | 4 days ago |
| MACD: Sell Signal | Oct 27, 12:00 PM | 4 days ago |
| RSI: Overbought | Oct 27, 11:35 AM | 4 days ago |
| RSI: Overbought | Oct 27, 11:05 AM | 4 days ago |
| RSI: Overbought | Oct 27, 10:35 AM | 4 days ago |
| RSI: Overbought | Oct 27, 10:20 AM | 4 days ago |
| RSI: Overbought | Oct 27, 9:40 AM | 4 days ago |
| SMA: Bullish | Oct 26, 3:55 PM | 5 days ago |
| MACD: Buy Signal | Oct 26, 3:50 PM | 5 days ago |
| SMA: Bullish | Oct 26, 3:35 PM | 5 days ago |
| MACD: Sell Signal | Oct 26, 2:50 PM | 5 days ago |
| SMA: Bearish | Oct 26, 2:10 PM | 5 days ago |
| SMA: Bearish | Oct 26, 2:10 PM | 5 days ago |
| SMA: Bullish | Oct 26, 2:05 PM | 5 days ago |
| SMA: Bearish | Oct 26, 2:00 PM | 5 days ago |
| SMA: Bullish | Oct 26, 1:55 PM | 5 days ago |
| SMA: Bullish | Oct 26, 1:50 PM | 5 days ago |
| SMA: Bearish | Oct 26, 1:45 PM | 5 days ago |
| SMA: Bullish | Oct 26, 1:35 PM | 5 days ago |
| SMA: Bearish | Oct 26, 1:30 PM | 5 days ago |
| SMA: Bullish | Oct 26, 1:25 PM | 5 days ago |
| SMA: Bearish | Oct 26, 1:20 PM | 5 days ago |
| MACD: Buy Signal | Oct 26, 1:00 PM | 5 days ago |
| MACD: Sell Signal | Oct 26, 12:45 PM | 5 days ago |
| SMA: Bearish | Oct 26, 12:40 PM | 5 days ago |
| SMA: Bullish | Oct 26, 12:05 PM | 5 days ago |
| SMA: Bullish | Oct 26, 11:00 AM | 5 days ago |
Key statistics
- Market cap
- 3.84B
- Enterprise value
- 4.08B
- Trailing P/E
- 0.00
- Forward P/E
- -43.32
- PEG ratio
- 0.00
- Price / sales
- 11.82
- Price / book
- 5.22
- EPS (TTM)
- -0.69
- Beta
- 0.76
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Profit margin
- -89.09%
- Revenue (TTM)
- 324.97M
- Revenue growth
- 65.70%
- Free cash flow
- -187.79M
- Total cash
- 297.67M
- Total debt
- 46.00M
- Return on equity
- -40.36%
- Shares outstanding
- 452.97M
- Short % of float
- 13.91%
- 50-day average
- 11.38
- 200-day average
- 5.81
Analyst view
Consensus: buy
- Target (low)
- 7.00
- Target (mean)
- 14.40
- Target (high)
- 20.00
- Strong buy2
- Buy5
- Hold2
- Sell0
- Strong sell0
Next earnings
Nov 5, 2026
Expected Nov 5, 2026. Consensus EPS estimate -0.08525.
Financials — quick view
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Nov 5, 2026 | Sep 30, 2026 | -0.08459 | — | — | — |
| Aug 6, 2026 | Jun 30, 2026 | -0.13346 | -0.11 | +0.02 | +17.58% |
| May 7, 2026 | Mar 31, 2026 | -0.19 | -0.19 | 0.00 | 0.00% |
| Feb 24, 2026 | Dec 31, 2025 | -0.22 | -0.18 | +0.04 | +18.18% |
| Nov 6, 2025 | Sep 30, 2025 | -0.29 | -0.25 | +0.04 | +13.79% |
| Aug 7, 2025 | Jun 30, 2025 | -0.29 | -0.33 | -0.04 | -13.79% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Oct 13, 2026 | Barclays | main | Overweight | Overweight |
| Oct 8, 2026 | Baird | main | Neutral | Neutral |
| Sep 30, 2026 | Wells Fargo | main | Overweight | Overweight |
| Sep 29, 2026 | HC Wainwright & Co. | main | Buy | Buy |
| Sep 17, 2026 | Barclays | main | Overweight | Overweight |
| Aug 25, 2026 | TD Cowen | main | Buy | Buy |
About Iovance Biotherapeutics, Inc.
Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationally. The company offers Amtagvi, an individualized T cell therapy for solid tumor cancer and for the treatment of adult patients with previously treated advanced, or unresectable or metastatic melanomal; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic melanoma and metastatic renal cell carcinoma. It also develops lifileucel for the treatment of melanoma, cervical cancer, non-small cell lung cancer (NSCLC), endometrial cancer, and head and neck squamous cell carcinoma (HNSCC); LN-145-S1 to treat melanoma and HNSCC; LN-145 Gen 3 and core biopsy for the treatment of NSCLC; LN-145 Gen 3 to treat melanoma and HNSCC; IOV-2001 to treat chronic lymphocytic leukemia and small lymphocytic lymphoma; IOV-4001 for the treatment of melanoma and NSCLC; and IOV-3001 for use in the TIL therapy treatment regimen. The company has collaborations and licensing agreements with National Institutes of Health; the National Cancer Institute; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in Philadelphia, Pennsylvania.
- Sector
- Healthcare
- Industry
- Biotechnology
- Country
- United States
- Website
- iovance.com
News
- Crude Oil Moves Lower; Caterpillar Shares Fall Following Q3 Results
- Iovance Biotherapeutics, Inc. (IOVA) Discusses Positive Lifileucel Data and Precision TIL Strategy in Non-small Cell Lung Cancer Transcript
- 12 Health Care Stocks Moving In Thursday's Intraday Session
- Iovance's Lifileucel Shows 25% Lung Cancer Response Rate, Targets 2027 FDA Filing
- Iovance Biotherapeutics (IOVA) Expected to Beat Earnings Estimates: Can the Stock Move Higher?
- 12 Health Care Stocks Moving In Thursday's Pre-Market Session
- Iovance Biotherapeutics Announced Updated Results From Cohorts 1 And 2 Of Its Phase 2 IOV-LUN-202 Trial; 24.6% Objective Response Rate In 69 Patients With Non-Squamous mNSCLC, Consistent With Previously Reported Results
- Iovance Reports Updated IOV-LUN-202 Results and Adds Precision TIL Strategy for Second-Line Metastatic Non-Small-Cell Lung Cancer (mNSCLC)
- Iovance Biotherapeutics to Host Webcast on Positive Data for TIL Therapy in Metastatic Non-Small Cell Lung Cancer (mNSCLC) and Broader Precision Medicine Strategy
- Best Momentum Stocks to Buy for October 27th
Your note
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Insider holders
| Insider | Relation | Latest transaction | Date | Shares held |
|---|---|---|---|---|
| BELLEMIN JEAN-MARC | Chief Financial Officer | Conversion of Exercise of derivative security | Jun 1, 2025 | 60,529 |
| BILINSKY IGOR P | Chief Operating Officer | Conversion of Exercise of derivative security | Sep 7, 2026 | 142,074 |
| GRAF FINCKENSTEIN FRIEDRICH | Officer | Conversion of Exercise of derivative security | Jun 4, 2026 | 140,111 |
| KIRBY DANIEL GORDON | Officer | Conversion of Exercise of derivative security | Aug 9, 2026 | 154,511 |
| MAYNARD RYAN D | Director | Sale | Nov 11, 2024 | 7,500 |
| PURI RAJ K | Officer | Conversion of Exercise of derivative security | Sep 7, 2026 | 256,364 |
Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| Blackrock Inc. | 8.16% | 36,957,681 | 313.40M | Jun 29, 2026 |
| MHR Fund Management, LLC | 6.39% | 28,967,103 | 245.64M | Jun 29, 2026 |
| State Street Corporation | 5.40% | 24,478,268 | 207.58M | Jun 29, 2026 |
| Two Sigma Investments, LP | 4.20% | 19,010,697 | 161.21M | Jun 29, 2026 |
| Vanguard Capital Management LLC | 4.02% | 18,204,248 | 154.37M | Jun 29, 2026 |
| Vanguard Portfolio Management LLC | 3.18% | 14,388,999 | 122.02M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 2.98% | 13,485,679 | 114.36M | Jun 29, 2026 |
| SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF | 2.48% | 11,251,093 | 95.41M | Sep 29, 2026 |
| iShares Trust-iShares Russell 2000 ETF | 2.27% | 10,291,732 | 87.27M | Sep 29, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund | 1.07% | 4,858,231 | 41.20M | Jun 29, 2026 |
| Fidelity Salem Street Trust-Fidelity Small Cap Index Fund | 0.96% | 4,351,328 | 36.90M | Jul 30, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund | 0.95% | 4,305,078 | 36.51M | Jun 29, 2026 |