Ionis Pharmaceuticals, Inc. IONS
Set alert
43.52 USD -0.87 -1.96%
At close · Oct 30
43.62 +0.10 +0.23%
After hours · Oct 30, 5:46 PM ET
43.27 Day range 45.12
42.38 52-week range 86.50
- YTD
- -44.99%
- 1 year
- -41.32%
- Open
- 44.69
- Prev close
- 44.39
- Mkt cap
- 7.23B
- Vol
- 1.52M
- Avg vol
- 3.16M
- EPS
- -3.48
- P/E
- 0.00
- Div yield
- 0.00%
More statistics
- Low
- 43.27
- High
- 45.12
- Forward P/E
- -37.97
- Beta
- 0.38
- Short ratio
- 5.20
- Inst. own
- 110.26%
- Dividend
- 0.00
- Ex-div date
- Earnings
- Nov 4, 2026
- 50-d avg
- 49.32
- 200-d avg
- 66.96
- 1y target
- 84.13
5D chart
Signals (110)
| Name | Time | Ago |
|---|---|---|
| SMA: Bearish | Oct 29, 3:50 PM | 2 days ago |
| SMA: Bullish | Oct 29, 3:25 PM | 2 days ago |
| SMA: Bullish | Oct 29, 2:50 PM | 2 days ago |
| MACD: Buy Signal | Oct 29, 2:50 PM | 2 days ago |
| RSI: Oversold | Oct 29, 2:10 PM | 2 days ago |
| RSI: Oversold | Oct 29, 1:50 PM | 2 days ago |
| SMA: Bearish | Oct 29, 1:00 PM | 2 days ago |
| SMA: Bullish | Oct 29, 12:55 PM | 2 days ago |
| SMA: Bearish | Oct 29, 12:30 PM | 2 days ago |
| SMA: Bearish | Oct 29, 11:40 AM | 2 days ago |
| SMA: Bearish | Oct 29, 11:35 AM | 2 days ago |
| SMA: Bullish | Oct 29, 11:20 AM | 2 days ago |
| SMA: Bullish | Oct 29, 11:00 AM | 2 days ago |
| SMA: Bearish | Oct 29, 10:55 AM | 2 days ago |
| MACD: Sell Signal | Oct 29, 10:30 AM | 2 days ago |
| SMA: Bullish | Oct 29, 10:15 AM | 2 days ago |
| RSI: Overbought | Oct 29, 10:15 AM | 2 days ago |
| SMA: Bearish | Oct 29, 10:05 AM | 2 days ago |
| RSI: Overbought | Oct 28, 3:50 PM | 3 days ago |
| MACD: Buy Signal | Oct 28, 3:30 PM | 3 days ago |
| RSI: Overbought | Oct 28, 3:30 PM | 3 days ago |
| SMA: Bullish | Oct 28, 3:25 PM | 3 days ago |
| SMA: Bearish | Oct 28, 3:10 PM | 3 days ago |
| SMA: Bullish | Oct 28, 3:05 PM | 3 days ago |
| MACD: Sell Signal | Oct 28, 3:00 PM | 3 days ago |
| SMA: Bearish | Oct 28, 2:50 PM | 3 days ago |
| SMA: Bullish | Oct 28, 2:10 PM | 3 days ago |
| SMA: Bearish | Oct 28, 2:05 PM | 3 days ago |
| SMA: Bullish | Oct 28, 1:20 PM | 3 days ago |
| SMA: Bearish | Oct 28, 1:10 PM | 3 days ago |
| MACD: Buy Signal | Oct 28, 12:55 PM | 3 days ago |
| SMA: Bullish | Oct 28, 12:40 PM | 3 days ago |
| SMA: Bearish | Oct 28, 12:00 PM | 3 days ago |
| SMA: Bullish | Oct 28, 11:55 AM | 3 days ago |
| SMA: Bullish | Oct 28, 11:55 AM | 3 days ago |
| SMA: Bearish | Oct 28, 11:50 AM | 3 days ago |
| SMA: Bearish | Oct 28, 11:50 AM | 3 days ago |
| SMA: Bearish | Oct 28, 11:25 AM | 3 days ago |
| MACD: Sell Signal | Oct 28, 11:10 AM | 3 days ago |
| SMA: Bearish | Oct 28, 11:05 AM | 3 days ago |
| SMA: Bullish | Oct 28, 10:45 AM | 3 days ago |
| SMA: Bearish | Oct 28, 10:40 AM | 3 days ago |
| MACD: Buy Signal | Oct 28, 10:10 AM | 3 days ago |
| SMA: Bullish | Oct 28, 9:55 AM | 3 days ago |
| SMA: Bearish | Oct 28, 9:45 AM | 3 days ago |
| SMA: Bullish | Oct 28, 9:40 AM | 3 days ago |
| SMA: Bearish | Oct 28, 9:30 AM | 3 days ago |
| SMA: Bearish | Oct 28, 9:30 AM | 3 days ago |
| MACD: Sell Signal | Oct 28, 9:30 AM | 3 days ago |
| RSI: Overbought | Oct 27, 3:45 PM | 4 days ago |
| MACD: Buy Signal | Oct 27, 2:45 PM | 4 days ago |
| SMA: Bullish | Oct 27, 2:40 PM | 4 days ago |
| SMA: Bullish | Oct 27, 2:40 PM | 4 days ago |
| SMA: Bearish | Oct 27, 2:10 PM | 4 days ago |
| MACD: Sell Signal | Oct 27, 2:10 PM | 4 days ago |
| MACD: Buy Signal | Oct 27, 1:30 PM | 4 days ago |
| SMA: Bullish | Oct 27, 1:20 PM | 4 days ago |
| SMA: Bearish | Oct 27, 12:40 PM | 4 days ago |
| SMA: Bullish | Oct 27, 12:35 PM | 4 days ago |
| SMA: Bullish | Oct 27, 11:55 AM | 4 days ago |
| SMA: Bullish | Oct 27, 11:50 AM | 4 days ago |
| SMA: Bearish | Oct 27, 11:20 AM | 4 days ago |
| MACD: Sell Signal | Oct 27, 11:10 AM | 4 days ago |
| SMA: Bearish | Oct 27, 11:05 AM | 4 days ago |
| RSI: Overbought | Oct 27, 10:40 AM | 4 days ago |
| SMA: Bullish | Oct 27, 10:20 AM | 4 days ago |
| SMA: Bearish | Oct 27, 10:10 AM | 4 days ago |
| SMA: Bullish | Oct 27, 10:05 AM | 4 days ago |
| SMA: Bearish | Oct 27, 10:00 AM | 4 days ago |
| RSI: Overbought | Oct 27, 9:40 AM | 4 days ago |
| RSI: Overbought | Oct 26, 3:50 PM | 5 days ago |
| SMA: Bullish | Oct 26, 3:10 PM | 5 days ago |
| SMA: Bullish | Oct 26, 3:00 PM | 5 days ago |
| SMA: Bearish | Oct 26, 2:40 PM | 5 days ago |
| SMA: Bullish | Oct 26, 2:30 PM | 5 days ago |
| SMA: Bearish | Oct 26, 2:20 PM | 5 days ago |
| SMA: Bullish | Oct 26, 2:15 PM | 5 days ago |
| SMA: Bearish | Oct 26, 2:10 PM | 5 days ago |
| MACD: Buy Signal | Oct 26, 2:05 PM | 5 days ago |
| SMA: Bullish | Oct 26, 2:00 PM | 5 days ago |
| RSI: Oversold | Oct 26, 1:35 PM | 5 days ago |
| SMA: Bearish | Oct 26, 12:25 PM | 5 days ago |
| SMA: Bullish | Oct 26, 12:05 PM | 5 days ago |
| SMA: Bearish | Oct 26, 11:25 AM | 5 days ago |
| SMA: Bearish | Oct 26, 11:25 AM | 5 days ago |
| SMA: Bullish | Oct 26, 11:05 AM | 5 days ago |
| MACD: Sell Signal | Oct 26, 10:40 AM | 5 days ago |
| SMA: Bearish | Oct 26, 10:30 AM | 5 days ago |
| RSI: Overbought | Oct 26, 10:15 AM | 5 days ago |
| RSI: Overbought | Oct 26, 9:45 AM | 5 days ago |
| SMA: Bullish | Oct 23, 3:35 PM | 1 week ago |
| SMA: Bearish | Oct 23, 3:30 PM | 1 week ago |
| SMA: Bullish | Oct 23, 3:25 PM | 1 week ago |
| SMA: Bullish | Oct 23, 3:15 PM | 1 week ago |
| MACD: Buy Signal | Oct 23, 3:15 PM | 1 week ago |
| SMA: Bearish | Oct 23, 2:35 PM | 1 week ago |
| SMA: Bullish | Oct 23, 2:20 PM | 1 week ago |
| SMA: Bearish | Oct 23, 2:15 PM | 1 week ago |
| SMA: Bullish | Oct 23, 2:10 PM | 1 week ago |
| SMA: Bearish | Oct 23, 1:30 PM | 1 week ago |
| SMA: Bullish | Oct 23, 1:25 PM | 1 week ago |
| MACD: Sell Signal | Oct 23, 1:10 PM | 1 week ago |
| SMA: Bearish | Oct 23, 1:00 PM | 1 week ago |
| SMA: Bullish | Oct 23, 12:10 PM | 1 week ago |
| SMA: Bearish | Oct 23, 11:45 AM | 1 week ago |
| SMA: Bullish | Oct 23, 11:40 AM | 1 week ago |
| SMA: Bearish | Oct 23, 11:35 AM | 1 week ago |
| SMA: Bullish | Oct 23, 11:10 AM | 1 week ago |
| SMA: Bearish | Oct 23, 11:05 AM | 1 week ago |
| SMA: Bullish | Oct 23, 10:40 AM | 1 week ago |
Ownership
Held by insiders 0.60%
Held by institutions 110.26%
Float held by institutions 110.92%
Institutions 703
Top institutional holders
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| FMR, LLC | 14.82% | 24,631,956 | 1.07B | Jun 29, 2026 |
| Capital World Investors | 13.04% | 21,669,226 | 943.04M | Jun 29, 2026 |
| Blackrock Inc. | 6.44% | 10,704,660 | 465.87M | Jun 29, 2026 |
| Vanguard Portfolio Management LLC | 4.73% | 7,859,529 | 342.05M | Jun 29, 2026 |
| Wellington Management Group, LLP | 4.60% | 7,651,415 | 332.99M | Jun 29, 2026 |
| Vanguard Capital Management LLC | 4.34% | 7,211,497 | 313.84M | Jun 29, 2026 |
Top mutual fund holders
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund | 5.12% | 8,503,655 | 370.08M | Aug 30, 2026 |
| Growth Fund of America | 4.61% | 7,668,655 | 333.74M | Sep 29, 2026 |
| VANGUARD SPECIALIZED FUNDS-Vanguard Health Care Fund | 3.74% | 6,212,640 | 270.37M | Jul 30, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 3.00% | 4,989,044 | 217.12M | Jun 29, 2026 |
| New Economy Fund | 2.93% | 4,868,802 | 211.89M | Sep 29, 2026 |
| SmallCap World Fund Inc | 2.68% | 4,458,145 | 194.02M | Sep 29, 2026 |
Insiders
| Insider | Relation | Latest transaction | Date | Shares held |
|---|---|---|---|---|
| BAROLDI JOSEPH | Officer | Sale | Jun 25, 2026 | 0 |
| BENNETT C FRANK | Officer | Sale | Jul 6, 2026 | 0 |
| BERTHELSEN SPENCER R | Director | Conversion of Exercise of derivative security | Jul 14, 2026 | 161,303 |
| BIRCHLER BRIAN | Officer | Sale | Apr 15, 2026 | 67,500 |
| GEARY RICHARD S | Officer | Sale | Nov 5, 2025 | 59,657 |
| HAYDEN MICHAEL REUBEN | Director | Purchase | Jul 30, 2026 | 0 |
Held by funds
178 US ETFs and mutual funds hold IONS · largest positions