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RYTM

Rhythm Pharmaceuticals, Inc.

Healthcare · USD

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Price alert · RYTM

All alert types
92.57 USD -0.50 -0.54%
As of Oct 30, 2026 Extended hours 92.57 0.00%
Bid
92.45 × 2
Ask
92.61 × 2
91.42 Day range 95.60
75.82 52-week range 117.62
YTD
-13.52%
1 year
-17.21%
Open
93.48
Prev close
93.07
Mkt cap
6.35B
Vol
431.66K
Avg vol
659.59K
EPS
-3.12
P/E
0.00
Div yield
0.00%
More statistics
Low
91.42
High
95.60
Forward P/E
-147.03
Beta
2.01
Short ratio
13.64
Inst. own
115.11%
Dividend
0.00
Ex-div date
Earnings
Nov 3, 2026
50-d avg
97.50
200-d avg
97.20
1y target
140.53

MAX chart

Chart tools
Interval
RYTM all-time price chart3.0432.862.692.4122.2Oct 17Aug 19May 21Mar 23Jan 25Oct 26

Key statistics

Market cap
6.36B
Enterprise value
6.30B
Trailing P/E
0.00
Forward P/E
-147.03
PEG ratio
0.00
Price / sales
26.52
Price / book
61.77
EPS (TTM)
-3.12
Beta
2.01
Dividend yield
0.00%
Payout ratio
0.00%
Profit margin
-85.59%
Revenue (TTM)
239.92M
Revenue growth
46.90%
Free cash flow
-130.59M
Total cash
330.90M
Total debt
109.78M
Return on equity
-117.05%
Shares outstanding
68.85M
Short % of float
16.11%
50-day average
97.50
200-day average
97.20

Analyst view

Consensus: strong buy

Strong buy
Price target (mean) 140.53 +51.8% upside
Target (low)
120.00
Target (mean)
140.53
Target (high)
160.00
Ratings (0m) 19 17 buy · 2 hold · 0 sell
  • Strong buy5
  • Buy12
  • Hold2
  • Sell0
  • Strong sell0

Next earnings

Nov 3, 2026

Expected Nov 3, 2026. Consensus EPS estimate -0.74252.

Earnings history

Financials — quick view

All financials
RYTM Revenue — quarterly 71.25M
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
RYTM Net income — quarterly -49.30M
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
RYTM EPS — quarterly -0.73
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026

Earnings

RYTM recent earnings
Report dateQuarter endingEPS estimateEPS reportedSurpriseSurprise %
Nov 3, 2026Sep 30, 2026-0.70968———
Aug 4, 2026Jun 30, 2026-0.80721-0.73+0.08+9.57%
May 5, 2026Mar 31, 2026-0.86-0.83+0.03+3.49%
Feb 26, 2026Dec 31, 2025-0.79-0.73+0.06+7.59%
Nov 4, 2025Sep 30, 2025-0.72-0.82-0.10-13.89%
Aug 5, 2025Jun 30, 2025-0.66-0.75-0.09-13.64%

Upgrades / downgrades

RYTM analyst upgrades and downgrades
DateFirmActionFromTo
Oct 16, 2026William Blairinit—Outperform
Oct 15, 2026JP MorganmainOverweightOverweight
Oct 12, 2026HC Wainwright & Co.mainBuyBuy
Oct 8, 2026RBC CapitalmainOutperformOutperform
Aug 28, 2026Deutsche Bankinit—Hold
Aug 7, 2026JP MorganmainOverweightOverweight

About Rhythm Pharmaceuticals, Inc.

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company's lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity. It is in Phase 3 clinical trials for treating acquired hypothalamic obesity, congenital hypothalamic obesity, pro-opiomelanocortin (POMC) and LEPR insufficiency obesities, SRC1 deficiency obesity, and SH2B1 deficiency obesity; and in phase 2 clinical trails for the treatment of Prader-Willi syndrome and MC4R deficiency. The company is also developing bivamelagon, an investigational oral small molecule MC4R agonist that is in phase 2 clinical trial for the treatment of MC4R pathway diseases; and RM-718, a next generation MC4R peptide agonist that is in phase 1 clinical trial for the treatment of hypothalamic obesity. The company was formerly known as Rhythm Metabolic, Inc. and changed its name to Rhythm Pharmaceuticals, Inc. in October 2015. Rhythm Pharmaceuticals, Inc. was founded in 2008 and is headquartered in Boston, Massachusetts.

Sector
Healthcare
Industry
Biotechnology
Country
United States
Website
rhythmtx.com

News

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Insider holders

RYTM insider holders
InsiderRelationLatest transactionDateShares held
CRAMER PAMELA J.OfficerConversion of Exercise of derivative securityJan 29, 202629,376
GOOD JENNIFER LDirectorConversion of Exercise of derivative securityJun 22, 202611,712
JEAN CHRISTOPHE RDirectorConversion of Exercise of derivative securityJun 22, 202611,712
MATHERS EDWARD T.DirectorConversion of Exercise of derivative securityJun 17, 202512,771
MAZABRAUD YANNOfficerConversion of Exercise of derivative securityAug 11, 202655,655
MCGIRR DAVID W JDirectorConversion of Exercise of derivative securityJun 22, 202611,712

Institution ownership

RYTM institution ownership
Holder% heldSharesValueReported
RA Capital Management, L.P.9.73%6,666,837616.08MJun 29, 2026
Blackrock Inc.8.98%6,156,902568.96MJun 29, 2026
Baker Bros. Advisors, LP8.18%5,604,483517.91MJun 29, 2026
Primecap Management Company4.62%3,168,853292.83MJun 29, 2026
Vanguard Portfolio Management LLC4.58%3,136,895289.88MJun 29, 2026
Vanguard Capital Management LLC4.39%3,005,977277.78MJun 29, 2026

Fund ownership

RYTM fund ownership
Holder% heldSharesValueReported
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund3.18%2,176,750201.15MJun 29, 2026
PRIMECAP Odyssey Funds-PRIMECAP Odyssey Aggressive Growth Fund2.87%1,967,269181.80MJul 30, 2026
SmallCap World Fund Inc2.58%1,769,519163.52MSep 29, 2026
VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund2.29%1,572,293145.30MJun 29, 2026
iShares Trust-iShares Russell 2000 ETF2.18%1,496,330138.28MSep 29, 2026
SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF1.73%1,184,359109.45MSep 29, 2026
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