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PTGX

Protagonist Therapeutics, Inc.

Healthcare · USD

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Price alert · PTGX

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144.85 USD +0.51 +0.35%
As of Oct 30, 2026 Extended hours 144.85 0.00%
Bid
144.84 × 2
Ask
144.91 × 2
142.54 Day range 146.00
75.95 52-week range 158.62
YTD
+65.85%
1 year
+86.06%
Open
144.34
Prev close
144.34
Mkt cap
9.37B
Vol
322.57K
Avg vol
648.58K
EPS
1.03
P/E
140.63
Div yield
0.00%
More statistics
Low
142.54
High
146.00
Forward P/E
-1459.30
Beta
1.52
Short ratio
12.29
Inst. own
119.68%
Dividend
0.00
Ex-div date
Earnings
Nov 5, 2026
50-d avg
143.05
200-d avg
116.32
1y target
178.57

5D chart

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Interval
1m5m15m30m
PTGX five-day price chart135.0137.9140.7143.6146.4Oct 23Oct 26Oct 27Oct 28Oct 29

Financial health

Altman Z-Score

129.01 Safe zone

Bankruptcy-risk model: below 1.81 distress, above 2.99 safe.

Piotroski F-Score

6 / 9 Average

Nine pass/fail tests of profitability, leverage and efficiency.

FMP rating

B-3 / 5 overall

  • DCF 1
  • Return on Equity 3
  • Return on Assets 5
  • Debt / Equity 4
  • P/E 1
  • P/B 1

Valuation

P/E -42.6×
FY 2016: -3.8×FY 2017: -10.0×FY 2018: -3.9×FY 2019: -2.4×FY 2020: -10.5×FY 2021: -12.9×FY 2022: -4.3×FY 2023: -16.5×FY 2024: 8.6×FY 2025: -42.6×
FY 2016 5y median -12.9× FY 2025
P/S 121×
FY 2016: 0.0×FY 2017: 18.3×FY 2018: 4.9×FY 2019: 790×FY 2020: 24.2×FY 2021: 57.9×FY 2022: 20.1×FY 2023: 21.7×FY 2024: 5.5×FY 2025: 121×
FY 2016 5y median 21.7× FY 2025
P/B 9.0×
FY 2016: -2.2×FY 2017: -3.6×FY 2018: -1.1×FY 2019: 2.3×FY 2020: 2.5×FY 2021: 5.3×FY 2022: 2.5×FY 2023: 3.9×FY 2024: 3.5×FY 2025: 9.0×
FY 2016 5y median 3.9× FY 2025
P/FCF 99.0×
FY 2016: -4.7×FY 2017: 115×FY 2018: -3.0×FY 2019: -4.3×FY 2020: -9.5×FY 2021: -14.5×FY 2022: -4.9×FY 2023: -18.4×FY 2024: 13.0×FY 2025: 99.0×
FY 2016 5y median -4.9× FY 2025
EV/EBITDA -42.4×
FY 2016: -3.8×FY 2017: -7.2×FY 2018: -1.7×FY 2019: -2.2×FY 2020: -9.4×FY 2021: -11.9×FY 2022: -3.3×FY 2023: -14.8×FY 2024: 8.1×FY 2025: -42.4×
FY 2016 5y median -11.9× FY 2025
EV/Sales 118×
FY 2016: 0.0×FY 2017: 13.1×FY 2018: 2.2×FY 2019: 721×FY 2020: 20.3×FY 2021: 53.6×FY 2022: 15.5×FY 2023: 18.6×FY 2024: 5.3×FY 2025: 118×
FY 2016 5y median 18.6× FY 2025
FCF Yield 1.0%
FY 2016: -21.2%FY 2017: 0.9%FY 2018: -33.5%FY 2019: -23.3%FY 2020: -10.5%FY 2021: -6.9%FY 2022: -20.4%FY 2023: -5.4%FY 2024: 7.7%FY 2025: 1.0%
FY 2016 5y median -5.4% FY 2025

Profitability

Gross Margin 97.3%
FY 2016: 0.0%FY 2017: 100.0%FY 2018: 100.0%FY 2019: 100.0%FY 2020: 100.0%FY 2021: 100.0%FY 2022: 100.0%FY 2023: 100.0%FY 2024: 100.0%FY 2025: 97.3%
FY 2016 5y median 100.0% FY 2025
Operating Margin -343.6%
FY 2016: 0.0%FY 2017: -188.9%FY 2018: -136.7%FY 2019: -34857.6%FY 2020: -225.4%FY 2021: -460.0%FY 2022: -494.2%FY 2023: -156.1%FY 2024: 58.2%FY 2025: -343.6%
FY 2016 5y median -343.6% FY 2025
Net Margin -282.8%
FY 2016: 0.0%FY 2017: -184.2%FY 2018: -125.9%FY 2019: -33414.3%FY 2020: -231.1%FY 2021: -458.9%FY 2022: -479.3%FY 2023: -131.6%FY 2024: 63.3%FY 2025: -282.8%
FY 2016 5y median -282.8% FY 2025
ROE -21.2%
FY 2016: 57.6%FY 2017: 36.4%FY 2018: 27.7%FY 2019: -96.5%FY 2020: -23.7%FY 2021: -41.8%FY 2022: -59.1%FY 2023: -23.5%FY 2024: 40.8%FY 2025: -21.2%
FY 2016 5y median -23.5% FY 2025
ROIC -25.2%
FY 2016: -37.3%FY 2017: -31.3%FY 2018: -36.6%FY 2019: -66.1%FY 2020: -22.6%FY 2021: -41.1%FY 2022: -59.9%FY 2023: -27.7%FY 2024: 35.7%FY 2025: -25.2%
FY 2016 5y median -27.7% FY 2025
ROA -19.4%
FY 2016: -39.6%FY 2017: -22.6%FY 2018: -27.9%FY 2019: -49.8%FY 2020: -20.4%FY 2021: -36.1%FY 2022: -51.4%FY 2023: -22.1%FY 2024: 37.0%FY 2025: -19.4%
FY 2016 5y median -22.1% FY 2025

Growth (YoY)

Revenue -89.4%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 54.1%FY 2019: -99.3%FY 2020: 12293.1%FY 2021: -4.4%FY 2022: -2.8%FY 2023: 125.7%FY 2024: 624.1%FY 2025: -89.4%
FY 2016 FY 2025
Operating Income -162.5%
FY 2016: -120.8%FY 2017: -16.0%FY 2018: -11.5%FY 2019: -90.5%FY 2020: 19.9%FY 2021: -95.1%FY 2022: -4.4%FY 2023: 28.7%FY 2024: 370.0%FY 2025: -162.5%
FY 2016 FY 2025
EPS (diluted) -148.5%
FY 2016: -127.0%FY 2017: 63.5%FY 2018: 16.7%FY 2019: -71.3%FY 2020: 35.6%FY 2021: -38.0%FY 2022: 4.9%FY 2023: 44.8%FY 2024: 404.3%FY 2025: -148.5%
FY 2016 FY 2025
Free Cash Flow -69.3%
FY 2016: -105.3%FY 2017: 110.6%FY 2018: -1673.1%FY 2019: 15.7%FY 2020: -71.7%FY 2021: -49.4%FY 2022: 0.0%FY 2023: 35.0%FY 2024: 358.0%FY 2025: -69.3%
FY 2016 FY 2025

Financial Health

Current Ratio 12.7×
FY 2016: 12.9×FY 2017: 3.5×FY 2018: 5.3×FY 2019: 4.1×FY 2020: 7.8×FY 2021: 7.7×FY 2022: 7.8×FY 2023: 16.7×FY 2024: 12.5×FY 2025: 12.7×
FY 2016 5y median 12.5× FY 2025
Quick Ratio 12.7×
FY 2016: 14.1×FY 2017: 3.8×FY 2018: 5.2×FY 2019: 4.1×FY 2020: 7.8×FY 2021: 7.7×FY 2022: 7.8×FY 2023: 16.7×FY 2024: 12.5×FY 2025: 12.7×
FY 2016 5y median 12.5× FY 2025
Debt / Equity 0.0×
FY 2016: 0.0×FY 2017: 0.0×FY 2018: 0.0×FY 2019: 0.2×FY 2020: 0.0×FY 2021: 0.0×FY 2022: 0.0×FY 2023: 0.0×FY 2024: 0.0×FY 2025: 0.0×
FY 2016 5y median 0.0× FY 2025
Net Debt / EBITDA 0.9×
FY 2016: 0.7×FY 2017: 2.9×FY 2018: 2.1×FY 2019: 0.2×FY 2020: 1.8×FY 2021: 1.0×FY 2022: 1.0×FY 2023: 2.5×FY 2024: -0.3×FY 2025: 0.9×
FY 2016 5y median 1.0× FY 2025
Interest Coverage 0.0×
FY 2016: 0.0×FY 2017: 0.0×FY 2018: 0.0×FY 2019: -476×FY 2020: -108×FY 2021: 0.0×FY 2022: 0.0×FY 2023: 0.0×FY 2024: 0.0×FY 2025: 0.0×
FY 2016 5y median 0.0× FY 2025

Dividends

Dividend Yield 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025
Payout Ratio 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025

Annual · latest fiscal year ends 2025-12-31