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OPKO Health, Inc. OPK

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1.73 USD -0.02 (-1.14%)

At closeNov 6, 2026, 7:34 PM EST

1.74 +0.01 +0.58%

After hours · Nov 6, 7:34 PM ET

1.71 Day range 1.86
1.10 52-week range 1.77
YTD
+37.30%
1 year
+25.36%
Market cap
1.28B
Revenue (ttm)
587.90M
Profit margin
-12.40%
EPS (ttm)
-0.16
Shares out
742.51M
Forward P/E
-5.04
YTD return
+37.30%
1-year return
+25.36%
Volume
6.90M
Avg volume
3.75M
Open
1.77
Previous close
1.75
Day's range
1.71 – 1.86
52-week range
1.10 – 1.77
Beta
1.53
Analysts
Buy
Price target
4.15 (+139.9%)
Earnings date
Feb 25, 2027

ALL -2.52 (-59.29%)

01019951999200220052008201120142017202020231.73

Key statistics

Enterprise value
1.42B
PEG ratio
93.65
Price / sales
2.18
Price / book
1.04
Dividend yield
0.00%
Payout ratio
0.00%
Revenue growth
4.30%
Free cash flow
54.76M
Total cash
300.76M
Total debt
398.08M
Return on equity
-5.88%
Short % of float
8.20%
50-day average
1.58
200-day average
1.35

Financials — quick view

All financials
OPK Revenue — quarterly 65.41M
2022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 20262026-Q3 2026
OPK Net income — quarterly -53.53M
2022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 20262026-Q3 2026
OPK EPS — quarterly -0.07
2022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 20262026-Q3 2026

Earnings

OPK recent earnings
Report dateQuarter endingEPS estimateEPS reportedSurpriseSurprise %
Feb 25, 2027Dec 30, 2026-0.08———
Nov 4, 2026Sep 30, 2026-0.068-0.05+0.02+26.47%
Jul 27, 2026Jun 30, 2026-0.08-0.01+0.07+87.50%
Apr 28, 2026Mar 31, 2026-0.07-0.070.000.00%
Feb 26, 2026Dec 31, 2025-0.07-0.04+0.03+42.86%
Oct 29, 2025Sep 30, 2025-0.020.03+0.05+250.00%

Upgrades / downgrades

OPK analyst upgrades and downgrades
DateFirmActionFromTo
Oct 16, 2026Piper SandlerreitOverweightOverweight
Oct 16, 2026Barrington ResearchupMarket PerformOutperform
Apr 29, 2026Barrington ResearchdownOutperformMarket Perform
Mar 2, 2026Barrington ResearchmainOutperformOutperform
Nov 20, 2025JP Morganinit—Neutral
Oct 31, 2025JefferiesdownBuyHold

About OPKO Health, Inc.

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida.

Sector
Healthcare
Industry
Diagnostics & Research
Country
United States
Website
opko.com

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Insider holders

OPK insider holders
InsiderRelationLatest transactionDateShares held
FROST PHILLIP MD ET ALChief Executive OfficerPurchaseNov 20, 20250
PAGANELLI JOHN ADirectorSaleNov 4, 20260

Institution ownership

OPK institution ownership
Holder% heldSharesValueReported
Rubric Capital Management LP6.40%47,791,24382.68MJun 29, 2026
Blackrock Inc.4.95%36,978,89363.97MJun 29, 2026
Vanguard Capital Management LLC2.01%14,968,93025.90MJun 29, 2026
Vanguard Portfolio Management LLC2.00%14,934,92425.84MJun 29, 2026
Geode Capital Management, LLC1.55%11,581,02720.04MJun 29, 2026
State Street Corporation1.38%10,309,07017.83MJun 29, 2026

Fund ownership

OPK fund ownership
Holder% heldSharesValueReported
iShares Trust-iShares Russell 2000 ETF1.38%10,318,70317.85MSep 29, 2026
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund1.31%9,753,39316.87MJun 29, 2026
VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund0.93%6,919,87611.97MJun 29, 2026
VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund0.66%4,914,7468.50MJun 29, 2026
Fidelity Salem Street Trust-Fidelity Small Cap Index Fund0.59%4,397,4607.61MAug 30, 2026
iShares Trust-iShares Russell 2000 Value ETF0.50%3,736,4356.46MSep 29, 2026