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OPKO Health, Inc. OPK

Set alert

Price alert · OPK

All alert types
1.66 USD 0.00 0.00%

At close · Oct 30

1.64 -0.02 -1.14%

After hours · Oct 30, 7:48 PM ET

Bid
1.66 × 1
Ask
1.67 × 1
1.64 Day range 1.69
1.10 52-week range 1.73
YTD
+31.75%
1 year
+13.70%
Open
1.66
Prev close
1.66
Mkt cap
1.24B
Vol
2.15M
Avg vol
3.59M
EPS
-0.09
P/E
0.00
Div yield
0.00%
More statistics
Low
1.64
High
1.69
Forward P/E
-4.83
Beta
1.50
Short ratio
7.73
Inst. own
27.61%
Dividend
0.00
Ex-div date
Earnings
Nov 4, 2026
50-d avg
1.56
200-d avg
1.34
1y target
4.15

2Y chart

Chart tools
Interval

Events in this range
  • Jul 31, 2025Earnings: -0.19; estimate -0.12; surprise -58.33%
  • Oct 29, 2025Earnings: 0.03; estimate -0.02; surprise 250%
  • Oct 31, 2025Downgrade: Jefferies · Buy → Hold
  • Nov 20, 2025Rating: JP Morgan · — → Neutral
  • Feb 26, 2026Earnings: -0.04; estimate -0.07; surprise 42.86%
  • Mar 2, 2026Rating: Barrington Research · Outperform → Outperform
  • Apr 28, 2026Earnings: -0.07; estimate -0.07; surprise 0%
  • Apr 29, 2026Downgrade: Barrington Research · Outperform → Market Perform
  • Jul 27, 2026Earnings: -0.01; estimate -0.08; surprise 87.5%
  • Oct 16, 2026Rating: Barrington Research · Market Perform → Outperform
  • Oct 16, 2026Rating: Piper Sandler · Overweight → Overweight
Signals (81)
NameDateAgo
MACD: Buy SignalOct 19, 20261 week ago
SMA: BullishOct 15, 20262 weeks ago
SMA: BullishOct 14, 20262 weeks ago
SMA: BearishOct 13, 20262 weeks ago
RSI: OversoldOct 13, 20262 weeks ago
SMA: BearishOct 6, 20263 weeks ago
MACD: Sell SignalSep 25, 20261 month ago
MACD: Buy SignalSep 18, 20261 month ago
MACD: Sell SignalSep 10, 20261 month ago
RSI: OverboughtSep 2, 20261 month ago
SMA: BullishAug 19, 20262 months ago
SMA: BullishAug 10, 20262 months ago
SMA: BullishJul 28, 20263 months ago
SMA: BullishJul 28, 20263 months ago
MACD: Buy SignalJul 28, 20263 months ago
RSI: OverboughtJul 28, 20263 months ago
SMA: BearishJul 13, 20263 months ago
SMA: BearishJul 13, 20263 months ago
RSI: OversoldJul 13, 20263 months ago
MACD: Sell SignalJul 2, 20264 months ago
RSI: OverboughtJul 1, 20264 months ago
MACD: Buy SignalJun 26, 20264 months ago
RSI: OverboughtJun 24, 20264 months ago
MACD: Sell SignalJun 15, 20264 months ago
RSI: OverboughtJun 11, 20264 months ago
RSI: OverboughtJun 3, 20265 months ago
RSI: OverboughtMay 28, 20265 months ago
SMA: BullishMay 20, 20265 months ago
MACD: Buy SignalMay 19, 20265 months ago
SMA: BearishApr 29, 20266 months ago
MACD: Sell SignalApr 29, 20266 months ago
MACD: Buy SignalApr 6, 20266 months ago
MACD: Sell SignalMar 27, 20267 months ago
MACD: Buy SignalMar 25, 20267 months ago
MACD: Sell SignalMar 20, 20267 months ago
MACD: Buy SignalMar 2, 20268 months ago
MACD: Sell SignalJan 27, 20269 months ago
SMA: BearishJan 22, 20269 months ago
SMA: BullishJan 21, 20269 months ago
SMA: BullishJan 21, 20269 months ago
MACD: Buy SignalJan 21, 20269 months ago
MACD: Sell SignalJan 16, 20269 months ago
SMA: BearishJan 14, 20269 months ago
SMA: BullishJan 7, 20269 months ago
MACD: Buy SignalJan 7, 20269 months ago
MACD: Sell SignalDec 18, 202510 months ago
MACD: Buy SignalNov 24, 202511 months ago
SMA: BearishOct 27, 20251 year ago
SMA: BearishOct 27, 20251 year ago
MACD: Sell SignalOct 13, 20251 year ago
SMA: BearishSep 25, 20251 year ago
SMA: BullishSep 24, 20251 year ago
SMA: BearishSep 19, 20251 year ago
SMA: BullishSep 18, 20251 year ago
MACD: Buy SignalSep 18, 20251 year ago
MACD: Sell SignalSep 15, 20251 year ago
MACD: Buy SignalSep 9, 20251 year ago
MACD: Sell SignalSep 4, 20251 year ago
SMA: BullishAug 13, 20251 year ago
MACD: Buy SignalAug 13, 20251 year ago
RSI: OversoldAug 1, 20251 year ago
MACD: Sell SignalJul 29, 20251 year ago
MACD: Buy SignalJun 30, 20251 year ago
MACD: Sell SignalJun 17, 20251 year ago
MACD: Buy SignalMay 14, 20251 year ago
RSI: OversoldMay 7, 20251 year ago
MACD: Sell SignalMay 6, 20251 year ago
MACD: Buy SignalApr 24, 20251 year ago
RSI: OversoldApr 21, 20251 year ago
RSI: OversoldApr 10, 20251 year ago
RSI: OversoldApr 8, 20251 year ago
SMA: BearishMar 31, 20251 year ago
MACD: Sell SignalMar 13, 20251 year ago
RSI: OverboughtMar 4, 20251 year ago
MACD: Buy SignalFeb 28, 20251 year ago
MACD: Sell SignalFeb 27, 20251 year ago
RSI: OverboughtFeb 18, 20251 year ago
SMA: BullishFeb 4, 20251 year ago
MACD: Buy SignalJan 21, 20251 year ago
MACD: Sell SignalJan 15, 20251 year ago
MACD: Buy SignalJan 13, 20251 year ago

Key statistics

Market cap
1.24B
Enterprise value
1.34B
Trailing P/E
0.00
Forward P/E
-4.83
PEG ratio
93.65
Price / sales
2.11
Price / book
1.05
EPS (TTM)
-0.09
Beta
1.50
Dividend yield
0.00%
Payout ratio
0.00%
Profit margin
-12.40%
Revenue (TTM)
587.90M
Revenue growth
4.30%
Free cash flow
54.76M
Total cash
300.76M
Total debt
398.08M
Return on equity
-5.88%
Shares outstanding
746.33M
Short % of float
8.20%
50-day average
1.56
200-day average
1.34

Analyst view

Consensus: buy

Buy
Price target (mean) 4.15 +150.0% upside
Target (low)
2.25
Target (mean)
4.15
Target (high)
8.50
Ratings (0m) 6 5 buy · 1 hold · 0 sell
  • Strong buy3
  • Buy2
  • Hold1
  • Sell0
  • Strong sell0

Next earnings

Nov 4, 2026

Expected Nov 4, 2026. Consensus EPS estimate -0.06333.

Earnings history

Financials — quick view

All financials
OPK Revenue — quarterly 163.58M
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
OPK Net income — quarterly -8.42M
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
OPK EPS — quarterly -0.01
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026

Earnings

OPK recent earnings
Report dateQuarter endingEPS estimateEPS reportedSurpriseSurprise %
Nov 4, 2026Sep 30, 2026-0.068———
Jul 27, 2026Jun 30, 2026-0.08-0.01+0.07+87.50%
Apr 28, 2026Mar 31, 2026-0.07-0.070.000.00%
Feb 26, 2026Dec 31, 2025-0.07-0.04+0.03+42.86%
Oct 29, 2025Sep 30, 2025-0.020.03+0.05+250.00%
Jul 31, 2025Jun 30, 2025-0.12-0.19-0.07-58.33%

Upgrades / downgrades

OPK analyst upgrades and downgrades
DateFirmActionFromTo
Oct 16, 2026Piper SandlerreitOverweightOverweight
Oct 16, 2026Barrington ResearchupMarket PerformOutperform
Apr 29, 2026Barrington ResearchdownOutperformMarket Perform
Mar 2, 2026Barrington ResearchmainOutperformOutperform
Nov 20, 2025JP Morganinit—Neutral
Oct 31, 2025JefferiesdownBuyHold

About OPKO Health, Inc.

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune system. This segment also engages in the development of Epstein Barr Virus vaccine; Rayaldee, a patented extended-release product for oral administration containing 30 mcg of a prohormone; OPK-88006 oral and injectable product to regulate blood glucose and reduce body weight; NGENLA, recombinant human growth hormone product developed for the long-term treatment of pediatric patients with growth hormone deficiency. The Diagnostics segment offers laboratory testing services, such as detection, diagnosis, evaluation, monitoring, and treatment of diseases, as well as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare under the BioReference brand; and 4Kscore test. OPKO Health, Inc. was founded in 2006 and is headquartered in Miami, Florida.

Sector
Healthcare
Industry
Diagnostics & Research
Country
United States
Website
opko.com

News

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Insider holders

OPK insider holders
InsiderRelationLatest transactionDateShares held
FROST PHILLIP MD ET ALChief Executive OfficerPurchaseNov 20, 20250
PAGANELLI JOHN ADirectorPurchaseMar 19, 2026403,515

Institution ownership

OPK institution ownership
Holder% heldSharesValueReported
Rubric Capital Management LP6.40%47,791,24379.33MJun 29, 2026
Blackrock Inc.4.95%36,978,89361.38MJun 29, 2026
Vanguard Capital Management LLC2.01%14,968,93024.85MJun 29, 2026
Vanguard Portfolio Management LLC2.00%14,934,92424.79MJun 29, 2026
Geode Capital Management, LLC1.55%11,581,02719.22MJun 29, 2026
State Street Corporation1.38%10,309,07017.11MJun 29, 2026

Fund ownership

OPK fund ownership
Holder% heldSharesValueReported
iShares Trust-iShares Russell 2000 ETF1.38%10,318,70317.13MSep 29, 2026
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund1.31%9,753,39316.19MJun 29, 2026
VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund0.93%6,919,87611.49MJun 29, 2026
VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund0.66%4,914,7468.16MJun 29, 2026
Fidelity Salem Street Trust-Fidelity Small Cap Index Fund0.58%4,352,3437.22MJul 30, 2026
iShares Trust-iShares Russell 2000 Value ETF0.50%3,736,4356.20MSep 29, 2026
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