Sectors

KRYS
Krystal Biotech, Inc.
312.58
1 x 311.72
2 x 314.96
bid
ask
+
2.27
0.73%
2 @ 07:10 AM
316.80 +4.22 (1.35%)
Ytd 26.79%
1y 132.35%
302.87
day range
317.21
122.80
52 week range
317.21
Open 309.53 Prev Close 310.31 Low 302.87 High 317.21 Mkt Cap 9.21B
Vol 311.31K Avg Vol 303.92K EPS 7.47 P/E 41.84 Forward P/E 30.39
Beta 0.49 Short Ratio 12.24 Inst. Own 98.63% Dividend N/A Div Yield N/A
Ex Div Date N/A Earning 08-03 50-d Avg 266.79 200-d Avg 223.72 1yr Est 318.22
Earning
Date For Estimate Reported Surprise surprise %
2026-05-04 2026-03 1.45 1.83 0.38 26.21%
2026-02-17 2025-12 1.62 N/A N/A N/A
2026-02-17 2025-12 1.62 1.7 0.08 4.94%
2025-11-03 2025-09 1.12 N/A N/A N/A
2025-11-03 2025-09 1.12 2.66 1.54 137.50%
2025-08-04 2025-06 1.08 1.29 0.21 19.44%
Upgrade / Downgrade
Date Firm Action From To
2026-05-05 Citigroup Upgrade Buy Buy
2026-05-05 Evercore ISI Group Upgrade Outperform Outperform
2026-05-04 HC Wainwright & Co. Upgrade Buy Buy
2026-03-27 Wolfe Research Upgrade Peer Perform
2026-02-25 Guggenheim Upgrade Buy Buy
2026-02-18 Citigroup Upgrade Buy Buy
Profile
Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey-Hailey disease; KB707 for solid tumors; KB304 for dynamic wrinkles; KB707 that is in Phase 1/2 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.
Insider Holder
Date Name Relation Quantity Description
2024-05-19 GANGOLLI JULIAN S. Director 0.00 Sale
2026-02-26 JANNEY DANIEL SPENCER Director 0.00 Sale
2026-03-03 KRISHNAN KRISH S Chief Executive Officer 1.62M Sale
2026-03-03 KRISHNAN SUMA M Officer, Director and Beneficial Owner 1.54M Sale
2026-03-01 ROMANO KATHRYN Officer 22.37K Sale
2026-02-18 ROSSI DINO A Director 78.69K Sale
Institution Ownership
Report Date Organization Position Value Percentage
2025-12-30 FMR, LLC 4.35M 1.36B 14.75%
2025-12-30 Blackrock Inc. 3.94M 1.23B 13.36%
2025-12-30 Avoro Capital Advisors LLC 2.89M 903.01M 9.80%
2026-03-30 Vanguard Portfolio Management LLC 1.46M 455.34M 4.94%
2025-12-30 State Street Corporation 1.34M 419.58M 4.55%
2026-03-30 Vanguard Capital Management LLC 1.17M 364.26M 3.95%
Fund Ownership
Report Date Organization Position Value Percentage
2026-03-30 Fidelity Select Portfolios-Select Biotechnology Portfolio 1.81M 564.68M 6.13%
2026-03-30 iShares Trust-iShares Core S&P Small-Cap ETF 1.55M 484.67M 5.26%
2025-12-30 VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund 822.89K 257.22M 2.79%
2026-03-30 Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund 785.53K 245.54M 2.66%
2025-12-30 SmallCap World Fund Inc 752.24K 235.14M 2.55%
2026-03-30 iShares Trust-iShares Russell 2000 ETF 600.77K 187.79M 2.04%