Karyopharm Therapeutics Inc. KPTI

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Price alert · KPTI

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0.66 USD -0.22 -24.76%

At close · Oct 30

0.65 -0.01 -1.24%

After hours · Oct 30, 7:57 PM ET

Bid
0.66 × 1
Ask
0.68 × 1
0.5868 Day range 0.902
0.315 52-week range 10.67
YTD
-91.01%
1 year
-88.89%
Open
0.902
Prev close
0.8798
Mkt cap
15.02M
Vol
3.52M
Avg vol
2.86M
EPS
-14.33
P/E
0.00
Div yield
0.00%
More statistics
Low
0.5868
High
0.902
Forward P/E
-0.87
Beta
0.15
Short ratio
19.48
Inst. own
48.24%
Dividend
0.00
Ex-div date
50-d avg
0.81746
200-d avg
0.959155
1y target
4.50

5D chart

Chart tools
Interval

Signals (144)
NameTimeAgo
SMA: BullishOct 30, 3:45 PM1 day ago
SMA: BullishOct 30, 3:30 PM1 day ago
MACD: Buy SignalOct 30, 3:30 PM1 day ago
SMA: BearishOct 30, 3:25 PM1 day ago
SMA: BullishOct 30, 3:20 PM1 day ago
SMA: BearishOct 30, 3:15 PM1 day ago
SMA: BullishOct 30, 3:10 PM1 day ago
MACD: Sell SignalOct 30, 2:20 PM1 day ago
SMA: BearishOct 30, 2:05 PM1 day ago
SMA: BearishOct 30, 2:05 PM1 day ago
SMA: BullishOct 30, 1:30 PM1 day ago
SMA: BearishOct 30, 1:25 PM1 day ago
SMA: BullishOct 30, 1:20 PM1 day ago
SMA: BullishOct 30, 12:55 PM1 day ago
SMA: BearishOct 30, 12:45 PM1 day ago
SMA: BullishOct 30, 12:40 PM1 day ago
MACD: Buy SignalOct 30, 12:25 PM1 day ago
MACD: Sell SignalOct 30, 11:25 AM1 day ago
MACD: Buy SignalOct 30, 11:10 AM1 day ago
SMA: BearishOct 30, 10:50 AM1 day ago
RSI: OversoldOct 30, 10:45 AM1 day ago
SMA: BullishOct 30, 10:40 AM1 day ago
RSI: OversoldOct 30, 9:55 AM1 day ago
SMA: BearishOct 30, 9:35 AM1 day ago
MACD: Sell SignalOct 30, 9:35 AM1 day ago
SMA: BearishOct 30, 9:30 AM1 day ago
RSI: OverboughtOct 29, 3:35 PM2 days ago
MACD: Buy SignalOct 29, 3:20 PM2 days ago
SMA: BullishOct 29, 3:15 PM2 days ago
SMA: BullishOct 29, 3:10 PM2 days ago
SMA: BearishOct 29, 2:25 PM2 days ago
MACD: Sell SignalOct 29, 2:25 PM2 days ago
SMA: BearishOct 29, 2:20 PM2 days ago
SMA: BullishOct 29, 2:10 PM2 days ago
SMA: BearishOct 29, 2:05 PM2 days ago
SMA: BullishOct 29, 1:00 PM2 days ago
MACD: Buy SignalOct 29, 1:00 PM2 days ago
SMA: BearishOct 29, 12:45 PM2 days ago
SMA: BullishOct 29, 12:05 PM2 days ago
SMA: BearishOct 29, 11:20 AM2 days ago
SMA: BearishOct 29, 10:30 AM2 days ago
MACD: Sell SignalOct 29, 10:10 AM2 days ago
RSI: OverboughtOct 29, 9:50 AM2 days ago
RSI: OverboughtOct 28, 3:35 PM3 days ago
RSI: OverboughtOct 28, 3:15 PM3 days ago
RSI: OverboughtOct 28, 3:00 PM3 days ago
RSI: OverboughtOct 28, 2:30 PM3 days ago
RSI: OverboughtOct 28, 2:15 PM3 days ago
SMA: BullishOct 28, 1:55 PM3 days ago
SMA: BearishOct 28, 1:50 PM3 days ago
SMA: BullishOct 28, 1:40 PM3 days ago
MACD: Buy SignalOct 28, 1:40 PM3 days ago
MACD: Sell SignalOct 28, 1:35 PM3 days ago
SMA: BearishOct 28, 1:25 PM3 days ago
MACD: Buy SignalOct 28, 1:25 PM3 days ago
SMA: BullishOct 28, 1:10 PM3 days ago
SMA: BullishOct 28, 1:00 PM3 days ago
SMA: BearishOct 28, 12:25 PM3 days ago
SMA: BearishOct 28, 12:25 PM3 days ago
SMA: BullishOct 28, 12:05 PM3 days ago
SMA: BearishOct 28, 11:50 AM3 days ago
SMA: BullishOct 28, 11:45 AM3 days ago
SMA: BearishOct 28, 11:40 AM3 days ago
MACD: Sell SignalOct 28, 11:40 AM3 days ago
SMA: BullishOct 28, 11:35 AM3 days ago
SMA: BearishOct 28, 11:20 AM3 days ago
RSI: OverboughtOct 28, 11:00 AM3 days ago
MACD: Buy SignalOct 28, 10:25 AM3 days ago
RSI: OverboughtOct 28, 10:25 AM3 days ago
SMA: BullishOct 28, 10:15 AM3 days ago
SMA: BearishOct 28, 10:05 AM3 days ago
SMA: BullishOct 28, 10:00 AM3 days ago
SMA: BearishOct 28, 9:55 AM3 days ago
MACD: Sell SignalOct 28, 9:45 AM3 days ago
SMA: BullishOct 28, 9:40 AM3 days ago
SMA: BearishOct 28, 9:30 AM3 days ago
RSI: OverboughtOct 27, 3:50 PM4 days ago
RSI: OverboughtOct 27, 3:05 PM4 days ago
SMA: BullishOct 27, 2:05 PM4 days ago
SMA: BullishOct 27, 2:05 PM4 days ago
MACD: Buy SignalOct 27, 2:00 PM4 days ago
MACD: Sell SignalOct 27, 1:20 PM4 days ago
SMA: BearishOct 27, 1:05 PM4 days ago
SMA: BearishOct 27, 1:05 PM4 days ago
SMA: BullishOct 27, 1:00 PM4 days ago
SMA: BullishOct 27, 1:00 PM4 days ago
SMA: BearishOct 27, 12:50 PM4 days ago
SMA: BearishOct 27, 12:50 PM4 days ago
SMA: BullishOct 27, 12:40 PM4 days ago
SMA: BullishOct 27, 12:40 PM4 days ago
SMA: BearishOct 27, 12:30 PM4 days ago
SMA: BearishOct 27, 12:30 PM4 days ago
SMA: BullishOct 27, 12:25 PM4 days ago
SMA: BearishOct 27, 12:20 PM4 days ago
SMA: BullishOct 27, 12:05 PM4 days ago
SMA: BearishOct 27, 11:55 AM4 days ago
SMA: BullishOct 27, 11:50 AM4 days ago
SMA: BearishOct 27, 11:45 AM4 days ago
SMA: BullishOct 27, 11:35 AM4 days ago
SMA: BullishOct 27, 11:35 AM4 days ago
MACD: Buy SignalOct 27, 11:35 AM4 days ago
MACD: Sell SignalOct 27, 11:15 AM4 days ago
SMA: BearishOct 27, 11:05 AM4 days ago
MACD: Buy SignalOct 27, 10:50 AM4 days ago
SMA: BullishOct 27, 10:35 AM4 days ago
SMA: BearishOct 27, 9:55 AM4 days ago
SMA: BearishOct 27, 9:55 AM4 days ago
MACD: Sell SignalOct 27, 9:55 AM4 days ago
SMA: BullishOct 27, 9:50 AM4 days ago
MACD: Buy SignalOct 27, 9:50 AM4 days ago
SMA: BullishOct 27, 9:45 AM4 days ago
SMA: BearishOct 27, 9:40 AM4 days ago
MACD: Sell SignalOct 27, 9:40 AM4 days ago
SMA: BullishOct 27, 9:35 AM4 days ago
SMA: BearishOct 27, 9:30 AM4 days ago
SMA: BearishOct 27, 9:30 AM4 days ago
SMA: BullishOct 26, 3:40 PM5 days ago
SMA: BullishOct 26, 3:40 PM5 days ago
SMA: BearishOct 26, 3:20 PM5 days ago
SMA: BearishOct 26, 3:20 PM5 days ago
SMA: BullishOct 26, 3:15 PM5 days ago
SMA: BearishOct 26, 3:10 PM5 days ago
SMA: BullishOct 26, 3:05 PM5 days ago
SMA: BullishOct 26, 3:05 PM5 days ago
SMA: BearishOct 26, 3:00 PM5 days ago
SMA: BullishOct 26, 2:50 PM5 days ago
MACD: Buy SignalOct 26, 2:50 PM5 days ago
SMA: BearishOct 26, 2:45 PM5 days ago
SMA: BullishOct 26, 2:35 PM5 days ago
SMA: BearishOct 26, 2:25 PM5 days ago
SMA: BearishOct 26, 2:25 PM5 days ago
SMA: BullishOct 26, 2:20 PM5 days ago
SMA: BullishOct 26, 2:20 PM5 days ago
SMA: BearishOct 26, 1:35 PM5 days ago
MACD: Sell SignalOct 26, 1:15 PM5 days ago
SMA: BearishOct 26, 12:55 PM5 days ago
SMA: BullishOct 26, 12:20 PM5 days ago
SMA: BullishOct 26, 12:00 PM5 days ago
SMA: BearishOct 26, 11:55 AM5 days ago
SMA: BullishOct 26, 11:35 AM5 days ago
SMA: BearishOct 26, 11:30 AM5 days ago
SMA: BullishOct 26, 10:50 AM5 days ago
SMA: BearishOct 26, 10:45 AM5 days ago
SMA: BullishOct 26, 10:30 AM5 days ago

Financial health

Altman Z-Score

-27.43 Distress zone

Bankruptcy-risk model: below 1.81 distress, above 2.99 safe.

Piotroski F-Score

2 / 9 Weak

Nine pass/fail tests of profitability, leverage and efficiency.

FMP rating

B-2 / 5 overall

  • DCF 5
  • Return on Equity 5
  • Return on Assets 1
  • Debt / Equity 1
  • P/E 1
  • P/B 1

Valuation

P/E -0.4×
FY 2016: -3.2×FY 2017: -3.4×FY 2018: -3.0×FY 2019: -5.9×FY 2020: -5.7×FY 2021: -3.9×FY 2022: -1.7×FY 2023: -0.7×FY 2024: -1.1×FY 2025: -0.4×
FY 2016 5y median -1.1× FY 2025
P/S 0.6×
FY 2016: 2288×FY 2017: 274×FY 2018: 17.5×FY 2019: 29.0×FY 2020: 10.3×FY 2021: 2.3×FY 2022: 1.8×FY 2023: 0.7×FY 2024: 0.6×FY 2025: 0.6×
FY 2016 5y median 0.7× FY 2025
P/B -0.3×
FY 2016: 2.2×FY 2017: 3.4×FY 2018: 2.9×FY 2019: 23.8×FY 2020: 22.0×FY 2021: -6.1×FY 2022: -16.7×FY 2023: -0.7×FY 2024: -0.4×FY 2025: -0.3×
FY 2016 5y median -0.7× FY 2025
P/FCF -1.1×
FY 2016: -4.2×FY 2017: -6.0×FY 2018: -3.3×FY 2019: -6.2×FY 2020: -6.9×FY 2021: -4.3×FY 2022: -1.9×FY 2023: -1.1×FY 2024: -0.6×FY 2025: -1.1×
FY 2016 5y median -1.1× FY 2025
EV/EBITDA -1.7×
FY 2016: -2.8×FY 2017: -2.9×FY 2018: -2.9×FY 2019: -6.5×FY 2020: -6.9×FY 2021: -4.9×FY 2022: -2.3×FY 2023: -1.9×FY 2024: -5.6×FY 2025: -1.7×
FY 2016 5y median -2.3× FY 2025
EV/Sales 1.7×
FY 2016: 1965×FY 2017: 231×FY 2018: 17.0×FY 2019: 28.9×FY 2020: 10.7×FY 2021: 2.3×FY 2022: 2.1×FY 2023: 1.5×FY 2024: 1.5×FY 2025: 1.7×
FY 2016 5y median 1.7× FY 2025
FCF Yield -93.6%
FY 2016: -24.0%FY 2017: -16.8%FY 2018: -30.4%FY 2019: -16.1%FY 2020: -14.4%FY 2021: -23.4%FY 2022: -53.8%FY 2023: -93.8%FY 2024: -154.9%FY 2025: -93.6%
FY 2016 5y median -93.6% FY 2025

Profitability

Gross Margin 95.9%
FY 2016: -56353.2%FY 2017: -6583.7%FY 2018: -431.9%FY 2019: 94.1%FY 2020: 97.5%FY 2021: 98.4%FY 2022: 96.7%FY 2023: 96.6%FY 2024: 95.9%FY 2025: 95.9%
FY 2016 5y median 96.6% FY 2025
Operating Margin -62.1%
FY 2016: -71903.9%FY 2017: -8133.2%FY 2018: -593.0%FY 2019: -462.9%FY 2020: -159.0%FY 2021: -46.8%FY 2022: -90.5%FY 2023: -88.7%FY 2024: -82.2%FY 2025: -62.1%
FY 2016 5y median -82.2% FY 2025
Net Margin -134.2%
FY 2016: -71153.9%FY 2017: -8036.4%FY 2018: -588.1%FY 2019: -488.1%FY 2020: -181.6%FY 2021: -59.1%FY 2022: -105.2%FY 2023: -98.0%FY 2024: -52.6%FY 2025: -134.2%
FY 2016 5y median -98.0% FY 2025
ROE 66.9%
FY 2016: -67.5%FY 2017: -99.6%FY 2018: -97.4%FY 2019: -401.0%FY 2020: -388.3%FY 2021: 155.7%FY 2022: 992.4%FY 2023: 105.1%FY 2024: 41.1%FY 2025: 66.9%
FY 2016 5y median 105.1% FY 2025
ROIC -236.6%
FY 2016: -67.6%FY 2017: -99.8%FY 2018: -61.1%FY 2019: -75.6%FY 2020: -67.5%FY 2021: -42.0%FY 2022: -48.2%FY 2023: -74.3%FY 2024: -123.1%FY 2025: -236.6%
FY 2016 5y median -74.3% FY 2025
ROA -180.8%
FY 2016: -60.7%FY 2017: -71.5%FY 2018: -52.3%FY 2019: -67.7%FY 2020: -62.7%FY 2021: -40.6%FY 2022: -46.1%FY 2023: -59.5%FY 2024: -46.5%FY 2025: -180.8%
FY 2016 5y median -46.5% FY 2025

Growth (YoY)

Revenue 0.6%
FY 2016: -38.4%FY 2017: 942.2%FY 2018: 1790.1%FY 2019: 34.8%FY 2020: 164.3%FY 2021: 94.1%FY 2022: -25.1%FY 2023: -7.0%FY 2024: -0.5%FY 2025: 0.6%
FY 2016 FY 2025
Operating Income 24.1%
FY 2016: 7.0%FY 2017: -17.9%FY 2018: -37.8%FY 2019: -5.2%FY 2020: 9.2%FY 2021: 42.8%FY 2022: -44.7%FY 2023: 8.9%FY 2024: 7.8%FY 2025: 24.1%
FY 2016 FY 2025
EPS (diluted) -90.5%
FY 2016: 12.0%FY 2017: 3.8%FY 2018: -11.8%FY 2019: -2.6%FY 2020: 15.4%FY 2021: 39.4%FY 2022: -22.3%FY 2023: 37.9%FY 2024: 49.9%FY 2025: -90.5%
FY 2016 FY 2025
Free Cash Flow 40.9%
FY 2016: 11.5%FY 2017: 12.6%FY 2018: -118.9%FY 2019: -18.3%FY 2020: 16.0%FY 2021: 29.6%FY 2022: -32.7%FY 2023: 38.0%FY 2024: -37.6%FY 2025: 40.9%
FY 2016 FY 2025

Financial Health

Current Ratio 1.1×
FY 2016: 8.0×FY 2017: 3.0×FY 2018: 7.1×FY 2019: 6.0×FY 2020: 4.6×FY 2021: 3.7×FY 2022: 5.3×FY 2023: 3.4×FY 2024: 1.7×FY 2025: 1.1×
FY 2016 5y median 3.4× FY 2025
Quick Ratio 1.1×
FY 2016: 8.0×FY 2017: 3.0×FY 2018: 7.1×FY 2019: 6.0×FY 2020: 4.5×FY 2021: 3.7×FY 2022: 5.2×FY 2023: 3.3×FY 2024: 1.6×FY 2025: 1.1×
FY 2016 5y median 3.3× FY 2025
Debt / Equity -0.8×
FY 2016: 0.0×FY 2017: 0.0×FY 2018: 0.6×FY 2019: 2.5×FY 2020: 2.6×FY 2021: -2.3×FY 2022: -10.8×FY 2023: -1.3×FY 2024: -1.0×FY 2025: -0.8×
FY 2016 5y median -1.3× FY 2025
Net Debt / EBITDA -1.2×
FY 2016: 0.5×FY 2017: 0.5×FY 2018: 0.1×FY 2019: 0.0×FY 2020: -0.3×FY 2021: 0.1×FY 2022: -0.3×FY 2023: -1.1×FY 2024: -3.4×FY 2025: -1.2×
FY 2016 5y median -1.1× FY 2025
Interest Coverage -2.0×
FY 2016: 0.0×FY 2017: 0.0×FY 2018: -72.2×FY 2019: -12.1×FY 2020: -6.3×FY 2021: -3.8×FY 2022: -5.7×FY 2023: -5.4×FY 2024: -3.2×FY 2025: -2.0×
FY 2016 5y median -3.8× FY 2025

Dividends

Dividend Yield 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025
Payout Ratio 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025

Annual · latest fiscal year ends 2025-12-31