Arrowhead Pharmaceuticals, Inc. ARWR

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59.53 USD -0.04 (-0.07%)

At closeNov 4, 2026, 7:52 AM EST

60.40 +0.87 +1.46%

Pre-market · Nov 4, 7:52 AM ET

59.25 Day range 60.89
37.06 52-week range 95.49
YTD
-10.33%
1 year
+50.29%
Market cap
8.41B
Revenue (ttm)
669.49M
Profit margin
-47.79%
EPS (ttm)
-2.28
Shares out
141.25M
Forward P/E
-11.96
YTD return
-10.33%
1-year return
+50.29%
Volume
1.33M
Avg volume
1.71M
Open
59.39
Previous close
59.57
Day's range
59.25 – 60.89
52-week range
37.06 – 95.49
Beta
1.37
Analysts
Strong Buy
Price target
107.71 (+80.9%)
Earnings date
Nov 24, 2026

2Y +39.47 (+196.76%)

255075Jan 25Jun 25Nov 25Mar 26Aug 2659.53

Key statistics

Enterprise value
8.20B
PEG ratio
0.00
Price / sales
12.56
Price / book
18.05
Dividend yield
0.00%
Payout ratio
0.00%
Revenue growth
171.00%
Free cash flow
-48.63M
Total cash
1.60B
Total debt
1.38B
Return on equity
-55.21%
Short % of float
10.79%
50-day average
69.24
200-day average
71.70

Financials — quick view

All financials
ARWR Revenue — quarterly 75.25M
2022-Q4 20222023-Q1 20222023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20232024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20242025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20252026-Q2 20262026-Q3 2026
ARWR Net income — quarterly -194.28M
2022-Q4 20222023-Q1 20222023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20232024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20242025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20252026-Q2 20262026-Q3 2026
ARWR EPS — quarterly -1.36
2022-Q4 20222023-Q1 20222023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20232024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20242025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20252026-Q2 20262026-Q3 2026

Earnings

ARWR recent earnings
Report dateQuarter endingEPS estimateEPS reportedSurpriseSurprise %
Nov 24, 2026Sep 30, 2026-1.52———
Aug 4, 2026Jun 30, 2026-1.28-1.36-0.08-6.25%
May 7, 2026Mar 31, 2026-1.09-0.93+0.16+14.68%
Feb 5, 2026Dec 31, 20250.600.22-0.38-63.33%
Nov 25, 2025Sep 30, 2025-0.11157-0.18-0.07-61.33%
Aug 7, 2025Jun 30, 2025-0.94-1.26-0.32-34.04%

Upgrades / downgrades

ARWR analyst upgrades and downgrades
DateFirmActionFromTo
Oct 15, 2026Chardan CapitalmainBuyBuy
Oct 15, 2026HC Wainwright & Co.reitBuyBuy
Sep 8, 2026Citigroupinit—Buy
Sep 1, 2026HC Wainwright & Co.reitBuyBuy
Aug 31, 2026Chardan CapitalmainBuyBuy
Aug 31, 2026RBC CapitalreitOutperformOutperform

About Arrowhead Pharmaceuticals, Inc.

Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. Its pipeline includes Plozasiran to reduce production of apolipoprotein C-III in Phase 3 studies; Zodasiran to reduce production of angiopoietin-like protein 3 in Phase 3 clinical trials; ARO-DIMER-PA, a dual functional RNAi molecule in a Phase 1/2a clinical trials; and ARO-PNPLA3, an investigational RNAi therapeutic in Phase 1 clinical trials. The company also develops ARO-INHBE, to reduce the hepatic expression of the INHBE gene and its secreted gene product, Activin E in Phase 1/2a clinical trials; ARO-ALK7 to silence adipocyte expression of the ACVR1C gene in Phase 1/2a clinical trials; ARO-RAGE to reduce production of the receptor for advanced glycation end products in Phase 1/2a clinical trials; and ARO-MAPT, an investigational RNAi-based therapy. In addition, it is developing ARO-C3 to reduce production of C3 in Phase 1/2a clinical trials; and ARO-CFB to reduce hepatic expression of CFB in a Phase 1/2a clinical trials. The company has collaboration and license Agreements with Glaxosmithkline Intellectual Property (No. 3) Limited; Takeda Pharmaceutical Company Limited; Amgen Inc.; and Sarepta Therapeutics, Inc. Arrowhead Pharmaceuticals, Inc. was founded in 2003 and is headquartered in Pasadena, California.

Sector
Healthcare
Industry
Biotechnology
Country
United States

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Insider holders

ARWR insider holders
InsiderRelationLatest transactionDateShares held
ANZALONE CHRISTOPHER RICHARDChief Executive OfficerSaleJan 1, 20263,792,740
APEL DANIEL JOSEPHChief Financial OfficerSaleApr 21, 2026162,905
FERRARI MAURODirectorSaleDec 25, 202569,053
GIVEN DOUGLAS BRUCEDirectorSaleDec 16, 2024124,167
HAMILTON JAMES COfficerSaleApr 22, 2026226,958
LU HONGBO BDirectorSaleMay 11, 202652,012

Institution ownership

ARWR institution ownership
Holder% heldSharesValueReported
Blackrock Inc.10.53%14,830,553882.86MJun 29, 2026
Avoro Capital Advisors LLC8.06%11,355,555676.00MJun 29, 2026
FMR, LLC5.71%8,039,804478.61MJun 29, 2026
Vanguard Portfolio Management LLC4.51%6,351,355378.10MJun 29, 2026
Vanguard Capital Management LLC4.34%6,110,953363.79MJun 29, 2026
State Street Corporation4.04%5,694,640339.00MJun 29, 2026

Fund ownership

ARWR fund ownership
Holder% heldSharesValueReported
iShares Trust-iShares Core S&P Mid-Cap ETF3.57%5,031,501299.53MSep 29, 2026
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund3.01%4,246,637252.80MJun 29, 2026
VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund2.18%3,067,819182.63MJun 29, 2026
Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund1.85%2,603,369154.98MAug 30, 2026
Invesco Exchange-Traded Fund Trust-Invesco S&P MidCap Momentum ETF1.28%1,799,303107.11MSep 29, 2026
SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF1.27%1,788,396106.46MSep 29, 2026