Arrowhead Pharmaceuticals, Inc. ARWR
At closeNov 3, 2026, 4:01 PM EST
After hours · Nov 3, 4:01 PM ET
- YTD
- -10.33%
- 1 year
- +50.29%
- Market cap
- 8.41B
- Revenue (ttm)
- 669.49M
- Profit margin
- -47.79%
- EPS (ttm)
- -2.28
- Shares out
- 141.25M
- Forward P/E
- -11.96
- YTD return
- -10.33%
- 1-year return
- +50.29%
- Volume
- 1.33M
- Avg volume
- 1.72M
- Open
- 59.39
- Previous close
- 59.57
- Day's range
- 59.25 – 60.89
- 52-week range
- 37.85 – 89.59
- Beta
- 1.37
- Analysts
- Strong Buy
- Price target
- 107.71 (+80.9%)
- Earnings date
- Nov 24, 2026
15m +0.40 (+0.68%)
Key statistics
- Enterprise value
- 8.20B
- PEG ratio
- 0.00
- Price / sales
- 12.56
- Price / book
- 18.05
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Revenue growth
- 171.00%
- Free cash flow
- -48.63M
- Total cash
- 1.60B
- Total debt
- 1.38B
- Return on equity
- -55.21%
- Short % of float
- 10.79%
- 50-day average
- 69.24
- 200-day average
- 71.70
Analyst view
Consensus: strong buy
- Target (low)
- 74.00
- Target (mean)
- 107.71
- Target (high)
- 126.00
- Strong buy4
- Buy10
- Hold1
- Sell0
- Strong sell0
Next earnings
Nov 24, 2026
Expected Nov 24, 2026. Consensus EPS estimate -1.50.
Financials — quick view
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Nov 24, 2026 | Sep 30, 2026 | -1.52 | — | — | — |
| Aug 4, 2026 | Jun 30, 2026 | -1.28 | -1.36 | -0.08 | -6.25% |
| May 7, 2026 | Mar 31, 2026 | -1.09 | -0.93 | +0.16 | +14.68% |
| Feb 5, 2026 | Dec 31, 2025 | 0.60 | 0.22 | -0.38 | -63.33% |
| Nov 25, 2025 | Sep 30, 2025 | -0.11157 | -0.18 | -0.07 | -61.33% |
| Aug 7, 2025 | Jun 30, 2025 | -0.94 | -1.26 | -0.32 | -34.04% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Oct 15, 2026 | Chardan Capital | main | Buy | Buy |
| Oct 15, 2026 | HC Wainwright & Co. | reit | Buy | Buy |
| Sep 8, 2026 | Citigroup | init | — | Buy |
| Sep 1, 2026 | HC Wainwright & Co. | reit | Buy | Buy |
| Aug 31, 2026 | Chardan Capital | main | Buy | Buy |
| Aug 31, 2026 | RBC Capital | reit | Outperform | Outperform |
About Arrowhead Pharmaceuticals, Inc.
Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. Its pipeline includes Plozasiran to reduce production of apolipoprotein C-III in Phase 3 studies; Zodasiran to reduce production of angiopoietin-like protein 3 in Phase 3 clinical trials; ARO-DIMER-PA, a dual functional RNAi molecule in a Phase 1/2a clinical trials; and ARO-PNPLA3, an investigational RNAi therapeutic in Phase 1 clinical trials. The company also develops ARO-INHBE, to reduce the hepatic expression of the INHBE gene and its secreted gene product, Activin E in Phase 1/2a clinical trials; ARO-ALK7 to silence adipocyte expression of the ACVR1C gene in Phase 1/2a clinical trials; ARO-RAGE to reduce production of the receptor for advanced glycation end products in Phase 1/2a clinical trials; and ARO-MAPT, an investigational RNAi-based therapy. In addition, it is developing ARO-C3 to reduce production of C3 in Phase 1/2a clinical trials; and ARO-CFB to reduce hepatic expression of CFB in a Phase 1/2a clinical trials. The company has collaboration and license Agreements with Glaxosmithkline Intellectual Property (No. 3) Limited; Takeda Pharmaceutical Company Limited; Amgen Inc.; and Sarepta Therapeutics, Inc. Arrowhead Pharmaceuticals, Inc. was founded in 2003 and is headquartered in Pasadena, California.
- Sector
- Healthcare
- Industry
- Biotechnology
- Country
- United States
- Website
- arrowheadpharma.com
News
Arrowhead Pharma To Present Three-Year Data From PALISADE Study And Open-Label Extension At American Heart Association Scientific Sessions 2026
Arrowhead Pharmaceuticals to Present Important Clinical Data at the American Heart Association Scientific Sessions 2026 Arrowhead Pharmaceuticals’ REDEMPLO Receives UK Marketing Authorization For Familial Chylomicronaemia Syndrome; NICE Recommends NHS Funding In England And Wales For Eligible Adults With Genetically Confirmed FCS
Adults Living with Familial Chylomicronaemia Syndrome (FCS) in England and Wales Have REDEMPLO® (Plozasiran) as a New Treatment Option to Reduce Triglycerides
Top 3 Health Care Stocks That Could Blast Off In October
Reviewing DBV Technologies (NASDAQ:DBVT) and Arrowhead Pharmaceuticals (NASDAQ:ARWR)
Arrowhead Pharmaceuticals: ARO-MAPT Results Unlock A New Platform HC Wainwright & Co. Reiterates Buy on Arrowhead Pharma, Maintains $120 Price Target
Arrowhead Pharmaceuticals, Inc. (ARWR) Discusses ARO-MAPT Interim Results and TRiM CNS Delivery Platform in Investigational CNS Pipeline Transcript
Arrowhead Pharmaceuticals Reports Up to 73% CSF Tau Reduction in Early ARO-MAPT Study
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Insider holders
| Insider | Relation | Latest transaction | Date | Shares held |
|---|---|---|---|---|
| ANZALONE CHRISTOPHER RICHARD | Chief Executive Officer | Sale | Jan 1, 2026 | 3,792,740 |
| APEL DANIEL JOSEPH | Chief Financial Officer | Sale | Apr 21, 2026 | 162,905 |
| FERRARI MAURO | Director | Sale | Dec 25, 2025 | 69,053 |
| GIVEN DOUGLAS BRUCE | Director | Sale | Dec 16, 2024 | 124,167 |
| HAMILTON JAMES C | Officer | Sale | Apr 22, 2026 | 226,958 |
| LU HONGBO B | Director | Sale | May 11, 2026 | 52,012 |
Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| Blackrock Inc. | 10.53% | 14,830,553 | 882.86M | Jun 29, 2026 |
| Avoro Capital Advisors LLC | 8.06% | 11,355,555 | 676.00M | Jun 29, 2026 |
| FMR, LLC | 5.71% | 8,039,804 | 478.61M | Jun 29, 2026 |
| Vanguard Portfolio Management LLC | 4.51% | 6,351,355 | 378.10M | Jun 29, 2026 |
| Vanguard Capital Management LLC | 4.34% | 6,110,953 | 363.79M | Jun 29, 2026 |
| State Street Corporation | 4.04% | 5,694,640 | 339.00M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| iShares Trust-iShares Core S&P Mid-Cap ETF | 3.57% | 5,031,501 | 299.53M | Sep 29, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 3.01% | 4,246,637 | 252.80M | Jun 29, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund | 2.18% | 3,067,819 | 182.63M | Jun 29, 2026 |
| Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund | 1.85% | 2,603,369 | 154.98M | Aug 30, 2026 |
| Invesco Exchange-Traded Fund Trust-Invesco S&P MidCap Momentum ETF | 1.28% | 1,799,303 | 107.11M | Sep 29, 2026 |
| SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF | 1.27% | 1,788,396 | 106.46M | Sep 29, 2026 |
