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Vertex Pharmaceuticals Incorporated VRTX

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Price alert · VRTX

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553.15 USD -5.73 -1.03%

At close · Nov 2

556.00 +2.85 +0.52%

After hours · Nov 2, 7:47 PM ET

Bid
553.96 × 1
Ask
556.05 × 1
544.09 Day range 568.67
403.16 52-week range 568.67
YTD
+22.01%
1 year
+29.98%
Open
560.88
Prev close
558.88
Mkt cap
140.11B
Vol
3.21M
Avg vol
1.20M
EPS
17.17
P/E
32.22
Div yield
0.00%
More statistics
Low
544.09
High
568.67
Forward P/E
27.09
Beta
0.28
Short ratio
3.66
Inst. own
98.10%
Dividend
0.00
Ex-div date
Earnings
Nov 2, 2026
50-d avg
523.21
200-d avg
479.21
1y target
571.46

1M chart

Chart tools
Interval
1m5m15m30m

Events in this range
  • Oct 8, 2026Rating: RBC Capital · Outperform → Outperform
  • Nov 2, 2026Earnings: —; estimate 4.82; surprise —%
Signals (7)
NameDateAgo
SMA: BullishOct 28, 20265 days ago
SMA: BearishOct 26, 20261 week ago
SMA: BullishOct 21, 20261 week ago
SMA: BullishOct 20, 20261 week ago
MACD: Buy SignalOct 20, 20261 week ago
SMA: BearishOct 16, 20262 weeks ago
SMA: BullishOct 15, 20262 weeks ago

Financial health

Altman Z-Score

9.14 Safe zone

Bankruptcy-risk model: below 1.81 distress, above 2.99 safe.

Piotroski F-Score

5 / 9 Average

Nine pass/fail tests of profitability, leverage and efficiency.

FMP rating

A-4 / 5 overall

  • DCF 4
  • Return on Equity 5
  • Return on Assets 5
  • Debt / Equity 3
  • P/E 2
  • P/B 1

Valuation

P/E 29.3×
FY 2016: -160×FY 2017: 141×FY 2018: 20.1×FY 2019: 47.8×FY 2020: 22.6×FY 2021: 24.2×FY 2022: 22.3×FY 2023: 29.0×FY 2024: -194×FY 2025: 29.3×
FY 2016 5y median 24.2× FY 2025
P/S 9.6×
FY 2016: 10.5×FY 2017: 15.0×FY 2018: 13.8×FY 2019: 13.5×FY 2020: 9.9×FY 2021: 7.5×FY 2022: 8.3×FY 2023: 10.6×FY 2024: 9.4×FY 2025: 9.6×
FY 2016 5y median 9.4× FY 2025
P/B 6.2×
FY 2016: 15.5×FY 2017: 18.4×FY 2018: 9.5×FY 2019: 9.2×FY 2020: 7.1×FY 2021: 5.6×FY 2022: 5.3×FY 2023: 6.0×FY 2024: 6.3×FY 2025: 6.2×
FY 2016 5y median 6.0× FY 2025
P/FCF 36.3×
FY 2016: 100.0×FY 2017: 63.7×FY 2018: 35.9×FY 2019: 37.6×FY 2020: 20.5×FY 2021: 23.5×FY 2022: 18.8×FY 2023: 32.0×FY 2024: -131×FY 2025: 36.3×
FY 2016 5y median 23.5× FY 2025
EV/EBITDA 23.6×
FY 2016: 233×FY 2017: 351×FY 2018: 56.7×FY 2019: 34.5×FY 2020: 17.2×FY 2021: 17.4×FY 2022: 14.5×FY 2023: 20.7×FY 2024: 207×FY 2025: 23.6×
FY 2016 5y median 20.7× FY 2025
EV/Sales 9.5×
FY 2016: 10.3×FY 2017: 14.6×FY 2018: 13.1×FY 2019: 12.9×FY 2020: 9.1×FY 2021: 6.7×FY 2022: 7.2×FY 2023: 9.7×FY 2024: 9.2×FY 2025: 9.5×
FY 2016 5y median 9.2× FY 2025
FCF Yield 2.8%
FY 2016: 1.0%FY 2017: 1.6%FY 2018: 2.8%FY 2019: 2.7%FY 2020: 4.9%FY 2021: 4.3%FY 2022: 5.3%FY 2023: 3.1%FY 2024: -0.8%FY 2025: 2.8%
FY 2016 5y median 3.1% FY 2025

Profitability

Gross Margin 85.0%
FY 2016: 87.6%FY 2017: 88.9%FY 2018: 86.6%FY 2019: 86.8%FY 2020: 88.1%FY 2021: 88.1%FY 2022: 87.9%FY 2023: 87.2%FY 2024: 86.1%FY 2025: 85.0%
FY 2016 5y median 87.2% FY 2025
Operating Margin 39.4%
FY 2016: 0.6%FY 2017: 5.0%FY 2018: 20.8%FY 2019: 28.8%FY 2020: 46.0%FY 2021: 36.7%FY 2022: 48.2%FY 2023: 38.8%FY 2024: -2.1%FY 2025: 39.4%
FY 2016 5y median 38.8% FY 2025
Net Margin 32.7%
FY 2016: -6.6%FY 2017: 10.6%FY 2018: 68.8%FY 2019: 28.3%FY 2020: 43.7%FY 2021: 30.9%FY 2022: 37.2%FY 2023: 36.7%FY 2024: -4.9%FY 2025: 32.7%
FY 2016 5y median 32.7% FY 2025
ROE 21.2%
FY 2016: -9.7%FY 2017: 13.0%FY 2018: 47.3%FY 2019: 19.3%FY 2020: 31.2%FY 2021: 23.2%FY 2022: 23.9%FY 2023: 20.6%FY 2024: -3.3%FY 2025: 21.2%
FY 2016 5y median 21.2% FY 2025
ROIC 18.1%
FY 2016: 0.4%FY 2017: -26.1%FY 2018: 12.4%FY 2019: 14.4%FY 2020: 25.1%FY 2021: 21.0%FY 2022: 21.8%FY 2023: 16.4%FY 2024: 2.6%FY 2025: 18.1%
FY 2016 5y median 18.1% FY 2025
ROA 15.1%
FY 2016: -3.9%FY 2017: 7.4%FY 2018: 33.6%FY 2019: 14.1%FY 2020: 23.1%FY 2021: 17.4%FY 2022: 18.3%FY 2023: 15.9%FY 2024: -2.4%FY 2025: 15.1%
FY 2016 5y median 15.9% FY 2025

Growth (YoY)

Revenue 9.6%
FY 2016: 64.9%FY 2017: 46.2%FY 2018: 22.5%FY 2019: 36.6%FY 2020: 49.1%FY 2021: 22.1%FY 2022: 17.9%FY 2023: 10.5%FY 2024: 11.7%FY 2025: 9.6%
FY 2016 FY 2025
Operating Income 2144.1%
FY 2016: 102.1%FY 2017: 1140.4%FY 2018: 415.4%FY 2019: 88.5%FY 2020: 138.5%FY 2021: -2.6%FY 2022: 54.8%FY 2023: -11.0%FY 2024: -106.1%FY 2025: 2144.1%
FY 2016 FY 2025
EPS (diluted) 836.5%
FY 2016: 80.1%FY 2017: 326.1%FY 2018: 677.9%FY 2019: -44.3%FY 2020: 128.2%FY 2021: -12.4%FY 2022: 42.3%FY 2023: 8.3%FY 2024: -115.0%FY 2025: 836.5%
FY 2016 FY 2025
Free Cash Flow 504.1%
FY 2016: 143.7%FY 2017: 226.1%FY 2018: 100.6%FY 2019: 27.2%FY 2020: 100.4%FY 2021: -19.5%FY 2022: 63.0%FY 2023: -16.5%FY 2024: -124.1%FY 2025: 504.1%
FY 2016 FY 2025

Financial Health

Current Ratio 2.9×
FY 2016: 2.3×FY 2017: 3.3×FY 2018: 3.4×FY 2019: 3.6×FY 2020: 4.3×FY 2021: 4.5×FY 2022: 4.8×FY 2023: 4.0×FY 2024: 2.7×FY 2025: 2.9×
FY 2016 5y median 4.0× FY 2025
Quick Ratio 2.5×
FY 2016: 2.2×FY 2017: 3.1×FY 2018: 3.3×FY 2019: 3.5×FY 2020: 4.2×FY 2021: 4.3×FY 2022: 4.7×FY 2023: 3.8×FY 2024: 2.4×FY 2025: 2.5×
FY 2016 5y median 3.8× FY 2025
Debt / Equity 0.2×
FY 2016: 0.7×FY 2017: 0.3×FY 2018: 0.1×FY 2019: 0.1×FY 2020: 0.1×FY 2021: 0.1×FY 2022: 0.1×FY 2023: 0.0×FY 2024: 0.1×FY 2025: 0.2×
FY 2016 5y median 0.1× FY 2025
Net Debt / EBITDA -0.2×
FY 2016: -4.5×FY 2017: -10.3×FY 2018: -2.9×FY 2019: -1.6×FY 2020: -1.5×FY 2021: -2.0×FY 2022: -2.2×FY 2023: -2.1×FY 2024: -5.8×FY 2025: -0.2×
FY 2016 5y median -2.1× FY 2025
Interest Coverage 358×
FY 2016: 0.1×FY 2017: 1.8×FY 2018: 18.6×FY 2019: 20.5×FY 2020: 49.1×FY 2021: 45.2×FY 2022: 78.6×FY 2023: 86.9×FY 2024: -7.6×FY 2025: 358×
FY 2016 5y median 78.6× FY 2025

Dividends

Dividend Yield 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025
Payout Ratio 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025

Annual · latest fiscal year ends 2025-12-31