Sectors

SYRE
Spyre Therapeutics, Inc.
87.71
2 x 66.06
2 x 113.92
bid
ask
-
2.65
2.93%
03:09 PM
timesize
Ytd167.74%
1y431.90%
87.05
day range
90.97
14.51
52 week range
110.17
Open89.15Prev Close90.36Low87.05High90.97Mkt Cap7.62B
Vol925.64KAvg Vol1.30MEPS-1.92P/EN/AForward P/E-26.31
Beta3.03Short Ratio12.43Inst. Own110.67%DividendN/ADiv YieldN/A
Ex Div DateN/AEarning11-0350-d Avg98.47200-d Avg60.371yr Est119.71

SYRE News

benzinga.com
Deutsche Bank Maintains Buy on Spyre Therapeutics, Lowers Price Target to $127

Deutsche Bank analyst David Hoang maintains Spyre Therapeutics (NASDAQ:SYRE) with a Buy and lower

SYRE Stock Sinks After Mixed SKYWAY Study Data in Rheumatoid Arthritis
zacks.com
SYRE Stock Sinks After Mixed SKYWAY Study Data in Rheumatoid Arthritis

Spyre's SPY072 shows activity in RA, but a smaller-than-expected benefit shifts its focus toward bro

Spyre Therapeutics Says Rheumatoid Arthritis Program Misses Internal Benchmark, Stock Tumbles
benzinga.com
Spyre Therapeutics Says Rheumatoid Arthritis Program Misses Internal Benchmark, Stock Tumbles

Spyre Therapeutics, Inc. (NASDAQ:SYRE) stock is trading lower on Wednesday after the company shared

Spyre Therapeutics Says Rheumatoid Arthritis Program Misses Internal Benchmark, Stock Tumbles
benzinga.com
Spyre Therapeutics Says Rheumatoid Arthritis Program Misses Internal Benchmark, Stock Tumbles

Spyre Therapeutics shared Phase 2 SKYWAY trial data for SPY072 in rheumatoid arthritis. The therapy

benzinga.com
Wedbush Maintains Outperform on Spyre Therapeutics, Lowers Price Target to $123

Wedbush analyst David Nierengarten maintains Spyre Therapeutics (NASDAQ:SYRE) with a Outperform a

12 Health Care Stocks Moving In Wednesday's Pre-Market Session
benzinga.com
12 Health Care Stocks Moving In Wednesday's Pre-Market Session

Gainers Nuwellis (NASDAQ:NUWE) stock increased by 27.2% to $1.22 during Wednesday's pre-market

Intuit, Zoom, Qfin Holdings And Other Big Stocks Moving Lower In Wednesday’s Pre-Market Session
benzinga.com
Intuit, Zoom, Qfin Holdings And Other Big Stocks Moving Lower In Wednesday’s Pre-Market Session

US stock futures mixed, Intuit shares dip 11.7% after reporting Q4 revenue of $4.35B and adjusted ea

benzinga.com
BTIG Maintains Buy on Spyre Therapeutics, Lowers Price Target to $121

BTIG analyst Julian Harrison maintains Spyre Therapeutics (NASDAQ:SYRE) with a Buy and lowers the

Why JOYY Shares Are Trading Higher; Here Are 20 Stocks Moving Premarket
benzinga.com
Why JOYY Shares Are Trading Higher; Here Are 20 Stocks Moving Premarket

JOYY Inc (NASDAQ: JOYY) reported Q2 earnings below estimates, but beat revenue expectations. Shares

12 Health Care Stocks Moving In Tuesday's After-Market Session
benzinga.com
12 Health Care Stocks Moving In Tuesday's After-Market Session

Gainers Alector (NASDAQ:ALEC) shares increased by 9.7% to $2.59 during Tuesday's after-market s

Spyre Therapeutics Announces Topline Results from the Rheumatoid Arthritis Sub-study of the SKYWAY Phase 2 Trial of SPY072
globenewswire.com
Spyre Therapeutics Announces Topline Results from the Rheumatoid Arthritis Sub-study of the SKYWAY P

Both doses of SPY072 demonstrated statistically significant benefits compared to placebo on one or m

Can Spyre's SPY772 HS Study Broaden Its Growth Story Beyond Core IBD?
zacks.com
Can Spyre's SPY772 HS Study Broaden Its Growth Story Beyond Core IBD?

SYRE expands into HS with SPY772, testing whether dual-pathway inhibition can strengthen outcomes in

Is SYRE a Buy Now as Clinical Catalysts Clash With Valuation Risk?
zacks.com
Is SYRE a Buy Now as Clinical Catalysts Clash With Valuation Risk?

Spyre has a broad clinical pipeline and cash runway, but elevated valuation makes upcoming readouts

SYRE Rallies 44.9% in 3 Months. Can Clinical Catalysts Sustain It?
zacks.com
SYRE Rallies 44.9% in 3 Months. Can Clinical Catalysts Sustain It?

Spyre's 2026 clinical catalysts and positive ulcerative colitis data fuel momentum, but its lofty va

Target To Rally Around 12%? Here Are 10 Top Analyst Forecasts For Tuesday
benzinga.com
Target To Rally Around 12%? Here Are 10 Top Analyst Forecasts For Tuesday

Wall Street analysts changed outlook on top names. See complete view of all changes, upgrades, downg

benzinga.com
BTIG Maintains Buy on Spyre Therapeutics, Raises Price Target to $132

BTIG analyst Julian Harrison maintains Spyre Therapeutics (NASDAQ:SYRE) with a Buy and raises the

benzinga.com
Spyre Therapeutics Launches New Combination Program SPY772, Comprising Long-Acting Anti-TL1A Antibod

To test the hypothesis of the SPY772 program, the company also announced the initiation of SKYLIGHT,

Spyre Therapeutics Announces Grants of Inducement Awards
globenewswire.com
Spyre Therapeutics Announces Grants of Inducement Awards

WALTHAM, Mass., Aug. 07, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Comp

Spyre's CEO Sold Stock, but Kept 567,000 Shares. Here's What Long-Term Investors Should Know
fool.com
Spyre's CEO Sold Stock, but Kept 567,000 Shares. Here's What Long-Term Investors Should Know

This disposition follows a staggering 500% one-year stock surge.

A Spyre Executive Sold Stock After a 500% Run. Here's What Long-Term Investors Should Know
fool.com
A Spyre Executive Sold Stock After a 500% Run. Here's What Long-Term Investors Should Know

This sale was executed under a pre-arranged plan as the stock posted a staggering return over 12 mon

SYRE's Q2 Loss Narrower Than Expected, Pipeline Progresses
zacks.com
SYRE's Q2 Loss Narrower Than Expected, Pipeline Progresses

Spyre beats Q2 loss estimates as positive phase II pipeline progress and upcoming data readouts fuel

benzinga.com
Wells Fargo Maintains Overweight on Spyre Therapeutics, Raises Price Target to $115

Wells Fargo analyst Yanan Zhu maintains Spyre Therapeutics (NASDAQ:SYRE) with a Overweight and ra

benzinga.com
Guggenheim Maintains Buy on Spyre Therapeutics, Raises Price Target to $130

Guggenheim analyst Yatin Suneja maintains Spyre Therapeutics (NASDAQ:SYRE) with a Buy and raises

benzinga.com
Wedbush Maintains Outperform on Spyre Therapeutics, Raises Price Target to $130

Wedbush analyst David Nierengarten maintains Spyre Therapeutics (NASDAQ:SYRE) with a Outperform a

benzinga.com
Spyre Therapeutics Q2 EPS $(0.36) Beats $(0.73) Estimate

Spyre Therapeutics (NASDAQ:SYRE) reported quarterly losses of $(0.36) per share which beat the analy

Spyre Therapeutics Reports Second Quarter 2026 Financial Results and Provides Corporate Update
globenewswire.com
Spyre Therapeutics Reports Second Quarter 2026 Financial Results and Provides Corporate Update

Announced positive topline induction data for SPY001 and SPY002 from Part A of the Phase 2 SKYLINE t

Brokerages Set Spyre Therapeutics, Inc. (NASDAQ:SYRE) PT at $101.42
defenseworld.net
Brokerages Set Spyre Therapeutics, Inc. (NASDAQ:SYRE) PT at $101.42

Shares of Spyre Therapeutics, Inc. (NASDAQ: SYRE - Get Free Report) have been given a consensus reco

Spyre Therapeutics (NASDAQ:SYRE) Trading 5.7% Higher   – Still a Buy?
defenseworld.net
Spyre Therapeutics (NASDAQ:SYRE) Trading 5.7% Higher – Still a Buy?

Spyre Therapeutics, Inc. (NASDAQ: SYRE - Get Free Report)'s stock price rose 5.7% during trading on

Goldman Sachs Posts Upbeat Q2 Earnings, Joins SK Hynix, Tower Semiconductor And Other Big Stocks Moving Higher On Tuesday
benzinga.com
Goldman Sachs Posts Upbeat Q2 Earnings, Joins SK Hynix, Tower Semiconductor And Other Big Stocks Mov

Goldman Sachs (NYSE: GS) shares surged 6.9% after beating earnings estimates. Other big gainers incl

benzinga.com
Mizuho Maintains Outperform on Spyre Therapeutics, Raises Price Target to $120

Mizuho analyst Joseph Catanzaro maintains Spyre Therapeutics (NASDAQ:SYRE) with a Outperform and

Rivian, Micron And Other Big Stocks Moving Lower In Tuesday’s Pre-Market Session
benzinga.com
Rivian, Micron And Other Big Stocks Moving Lower In Tuesday’s Pre-Market Session

U.S. stock futures mixed, Nasdaq 100 falls 200 pts. Rivian (RIVN) drops after public offering announ

Spyre Therapeutics Announces Grants of Inducement Awards
globenewswire.com
Spyre Therapeutics Announces Grants of Inducement Awards

WALTHAM, Mass., July 02, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Comp

Spyre Therapeutics: Deep And Diverse Immunology Pipeline Awaiting Data
seekingalpha.com
Spyre Therapeutics: Deep And Diverse Immunology Pipeline Awaiting Data

Spyre Therapeutics is building a long-acting antibody platform across IBD and rheumatology. However,

Is SYRE Stock a Buy Now or a Wait-and-See Biotech Story Today
zacks.com
Is SYRE Stock a Buy Now or a Wait-and-See Biotech Story Today

Spyre Therapeutics  SYRE has given investors a classic biotech dilemma. The pipeline is advancing, t

Spyre Therapeutics Stock Outlook Hinges on 2026 Study Catalysts
zacks.com
Spyre Therapeutics Stock Outlook Hinges on 2026 Study Catalysts

Spyre Therapeutics  SYRE has become a closely watched clinical-stage biotech stock as investors look

SYRE and Spyre Ride New IBD Trends in Biotech Drug Design
zacks.com
SYRE and Spyre Ride New IBD Trends in Biotech Drug Design

SYRE is targeting major IBD drug trends with long-acting antibodies and combination therapies, but i

Spyre Therapeutics: A Platform Where The Combination Strategy Is The Real Asset
seekingalpha.com
Spyre Therapeutics: A Platform Where The Combination Strategy Is The Real Asset

Spyre is building a modular immunology platform targeting IBD and rheumatic diseases with internally

Biotech ETF Index Surges 10% After Rebalance
etftrends.com
Biotech ETF Index Surges 10% After Rebalance

After a sweeping semi-annual rebalance, the biotech index underlying the ALPS Medical Breakthroughs

What's Going On With Spyre Therapeutics Stock On Wednesday?
benzinga.com
What's Going On With Spyre Therapeutics Stock On Wednesday?

Spyre Therapeutics falls 12% amid major insider stock sales. Explore the technical data and market s

FedEx, Cerebras Systems And Other Big Stocks Moving Lower In Wednesday’s Pre-Market Session
benzinga.com
FedEx, Cerebras Systems And Other Big Stocks Moving Lower In Wednesday’s Pre-Market Session

U.S. stock futures mixed, Nasdaq 100 up 100 points. FedEx falls after Q4 results, beating estimates

Why Leifras Shares Are Trading Higher By Around 23%; Here Are 20 Stocks Moving Premarket
benzinga.com
Why Leifras Shares Are Trading Higher By Around 23%; Here Are 20 Stocks Moving Premarket

Leifras Co Ltd (NASDAQ: LFS) rose in pre-market trading after acquiring SWIFT JAPAN for JPY454.6 mil

12 Health Care Stocks Moving In Tuesday's After-Market Session
benzinga.com
12 Health Care Stocks Moving In Tuesday's After-Market Session

Gainers Quoin Pharmaceuticals (NASDAQ:QNRX) shares rose 40.3% to $4.56 during Tuesday's after-m

benzinga.com
Deutsche Bank Maintains Buy on Spyre Therapeutics, Raises Price Target to $135

Deutsche Bank analyst David Hoang maintains Spyre Therapeutics (NASDAQ:SYRE) with a Buy and raise

Why Sagtec Global Shares Are Trading Higher By Around 76%; Here Are 20 Stocks Moving Premarket
benzinga.com
Why Sagtec Global Shares Are Trading Higher By Around 76%; Here Are 20 Stocks Moving Premarket

SAGTEC GLOBAL (NASDAQ: SAGT) gained 75.6% in pre-market trading after projecting 35% revenue growth

benzinga.com
Spyre Therapeutics Announces 12-Week Induction Data From Part A Of Phase 2 SKYLINE Study Of SPY002 T

Spyre Therapeutics, Inc. (NASDAQ: SYRE), a clinical-stage biotechnology company committed to develop

benzinga.com
Deutsche Bank Maintains Buy on Spyre Therapeutics, Raises Price Target to $115

Deutsche Bank analyst David Hoang maintains Spyre Therapeutics (NASDAQ:SYRE) with a Buy and raise

Navitas Semiconductor, Abivax, MiniMed And Other Big Stocks Moving Higher On Wednesday
benzinga.com
Navitas Semiconductor, Abivax, MiniMed And Other Big Stocks Moving Higher On Wednesday

Dow falls 296 points. Navitas Semi rises on partnership with Nvidia. Other gainers: ABVX, MMED, KELY

benzinga.com
Spyre Therapeutics Completes Enrollment For All Sub-Studies In SKYWAY Basket Trial Of SPY072 In Rheu

Enrollment for psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA) sub-studies of the SKYW

benzinga.com
Spyre Therapeutics Expands SPY003 Rights Beyond IBD Through Amended Paragon License Agreement

On May 29, 2026, the Company entered into the First Amendment to Amended and Restated License Agreem

Norwegian Cruise Line, Aura Biosciences And Other Big Stocks Moving Lower In Monday's Pre-Market Session
benzinga.com
Norwegian Cruise Line, Aura Biosciences And Other Big Stocks Moving Lower In Monday's Pre-Market Ses

US stock futures lower, Dow futures down 200 points. Norwegian Cruise Line shares fall after Q1 resu