Silence Therapeutics plc SLN
Set alert
19.75 USD -0.05 -0.25%
At close · Oct 30
19.75 0.00 0.00%
After hours · Oct 30, 4:00 PM ET
19.74 Day range 19.80
4.30 52-week range 19.80
- YTD
- +224.84%
- 1 year
- +170.18%
- Open
- 19.74
- Prev close
- 19.80
- Mkt cap
- 1.23B
- Vol
- 621.43K
- Avg vol
- 2.77M
- EPS
- -1.29
- P/E
- 0.00
- Div yield
- 0.00%
More statistics
- Low
- 19.74
- High
- 19.80
- Forward P/E
- -51.97
- Beta
- 1.45
- Short ratio
- 2.70
- Inst. own
- 47.74%
- Dividend
- 0.00
- Ex-div date
- Earnings
- Nov 5, 2026
- 50-d avg
- 13.35
- 200-d avg
- 8.99
- 1y target
- 19.75
2Y chart
Events in this range
- Aug 7, 2025Earnings: -0.54; estimate -0.27; surprise -100%
- Sep 16, 2025Rating: HC Wainwright & Co. · Buy → Buy
- Nov 6, 2025Earnings: -0.45; estimate -0.4; surprise -12.5%
- Mar 5, 2026Earnings: -0.25; estimate -0.32; surprise 21.88%
- Mar 13, 2026Rating: HC Wainwright & Co. · Buy → Buy
- May 7, 2026Earnings: -0.32; estimate -0.33; surprise 3.03%
- Jun 17, 2026Rating: HC Wainwright & Co. · Buy → Buy
- Jun 24, 2026Rating: Cantor Fitzgerald · — → Overweight
- Aug 10, 2026Earnings: -0.26; estimate -0.13866; surprise -87.51%
- Aug 11, 2026Rating: Morgan Stanley · Overweight → Overweight
- Oct 21, 2026Downgrade: HC Wainwright & Co. · Buy → Neutral
Signals (104)
| Name | Date | Ago |
|---|---|---|
| SMA: Bullish | Oct 19, 2026 | 1 week ago |
| MACD: Buy Signal | Oct 19, 2026 | 1 week ago |
| RSI: Overbought | Oct 19, 2026 | 1 week ago |
| RSI: Oversold | Oct 16, 2026 | 2 weeks ago |
| RSI: Oversold | Oct 2, 2026 | 4 weeks ago |
| RSI: Oversold | Sep 29, 2026 | 1 month ago |
| SMA: Bearish | Sep 18, 2026 | 1 month ago |
| MACD: Sell Signal | Aug 20, 2026 | 2 months ago |
| MACD: Buy Signal | Aug 10, 2026 | 2 months ago |
| RSI: Overbought | Aug 10, 2026 | 2 months ago |
| MACD: Sell Signal | Jul 30, 2026 | 3 months ago |
| MACD: Buy Signal | Jul 22, 2026 | 3 months ago |
| RSI: Overbought | Jul 22, 2026 | 3 months ago |
| MACD: Sell Signal | Jul 10, 2026 | 3 months ago |
| RSI: Overbought | Jun 24, 2026 | 4 months ago |
| SMA: Bullish | Jun 18, 2026 | 4 months ago |
| SMA: Bearish | Jun 16, 2026 | 4 months ago |
| SMA: Bullish | Jun 15, 2026 | 4 months ago |
| MACD: Buy Signal | Jun 12, 2026 | 4 months ago |
| SMA: Bullish | Jun 11, 2026 | 4 months ago |
| SMA: Bearish | Jun 9, 2026 | 4 months ago |
| SMA: Bearish | Jun 5, 2026 | 4 months ago |
| MACD: Sell Signal | Jun 5, 2026 | 4 months ago |
| SMA: Bullish | Jun 4, 2026 | 4 months ago |
| MACD: Buy Signal | Jun 4, 2026 | 4 months ago |
| MACD: Sell Signal | Jun 2, 2026 | 5 months ago |
| SMA: Bearish | Jun 1, 2026 | 5 months ago |
| MACD: Buy Signal | May 29, 2026 | 5 months ago |
| SMA: Bullish | May 26, 2026 | 5 months ago |
| SMA: Bullish | May 20, 2026 | 5 months ago |
| SMA: Bearish | May 19, 2026 | 5 months ago |
| SMA: Bearish | May 15, 2026 | 5 months ago |
| MACD: Sell Signal | Apr 30, 2026 | 6 months ago |
| RSI: Overbought | Apr 22, 2026 | 6 months ago |
| RSI: Overbought | Apr 20, 2026 | 6 months ago |
| RSI: Overbought | Apr 16, 2026 | 6 months ago |
| SMA: Bullish | Apr 13, 2026 | 6 months ago |
| MACD: Buy Signal | Apr 13, 2026 | 6 months ago |
| SMA: Bearish | Apr 9, 2026 | 6 months ago |
| SMA: Bullish | Apr 8, 2026 | 6 months ago |
| SMA: Bearish | Apr 6, 2026 | 6 months ago |
| SMA: Bullish | Apr 2, 2026 | 7 months ago |
| SMA: Bullish | Apr 1, 2026 | 7 months ago |
| SMA: Bearish | Mar 24, 2026 | 7 months ago |
| SMA: Bearish | Mar 23, 2026 | 7 months ago |
| MACD: Sell Signal | Mar 20, 2026 | 7 months ago |
| RSI: Overbought | Mar 11, 2026 | 7 months ago |
| SMA: Bullish | Mar 6, 2026 | 7 months ago |
| SMA: Bearish | Mar 5, 2026 | 8 months ago |
| SMA: Bullish | Mar 4, 2026 | 8 months ago |
| SMA: Bearish | Mar 3, 2026 | 8 months ago |
| SMA: Bullish | Mar 2, 2026 | 8 months ago |
| SMA: Bullish | Feb 27, 2026 | 8 months ago |
| MACD: Buy Signal | Feb 17, 2026 | 8 months ago |
| RSI: Oversold | Feb 4, 2026 | 8 months ago |
| MACD: Sell Signal | Jan 27, 2026 | 9 months ago |
| SMA: Bearish | Jan 26, 2026 | 9 months ago |
| MACD: Buy Signal | Jan 23, 2026 | 9 months ago |
| SMA: Bullish | Jan 21, 2026 | 9 months ago |
| SMA: Bearish | Jan 16, 2026 | 9 months ago |
| SMA: Bearish | Dec 16, 2025 | 10 months ago |
| SMA: Bullish | Dec 15, 2025 | 10 months ago |
| SMA: Bearish | Dec 9, 2025 | 10 months ago |
| MACD: Sell Signal | Dec 9, 2025 | 10 months ago |
| MACD: Buy Signal | Dec 5, 2025 | 11 months ago |
| SMA: Bullish | Dec 3, 2025 | 11 months ago |
| SMA: Bearish | Dec 2, 2025 | 11 months ago |
| MACD: Sell Signal | Nov 3, 2025 | 12 months ago |
| RSI: Overbought | Oct 28, 2025 | 1 year ago |
| RSI: Overbought | Oct 20, 2025 | 1 year ago |
| RSI: Overbought | Oct 16, 2025 | 1 year ago |
| SMA: Bullish | Oct 13, 2025 | 1 year ago |
| SMA: Bullish | Oct 6, 2025 | 1 year ago |
| SMA: Bearish | Oct 3, 2025 | 1 year ago |
| SMA: Bearish | Sep 30, 2025 | 1 year ago |
| SMA: Bullish | Sep 26, 2025 | 1 year ago |
| SMA: Bullish | Sep 26, 2025 | 1 year ago |
| SMA: Bearish | Sep 25, 2025 | 1 year ago |
| SMA: Bullish | Sep 23, 2025 | 1 year ago |
| MACD: Buy Signal | Sep 18, 2025 | 1 year ago |
| MACD: Sell Signal | Sep 11, 2025 | 1 year ago |
| SMA: Bearish | Sep 9, 2025 | 1 year ago |
| SMA: Bullish | Sep 5, 2025 | 1 year ago |
| MACD: Buy Signal | Sep 5, 2025 | 1 year ago |
| SMA: Bearish | Aug 14, 2025 | 1 year ago |
| SMA: Bullish | Aug 13, 2025 | 1 year ago |
| SMA: Bearish | Aug 5, 2025 | 1 year ago |
| MACD: Sell Signal | Jul 18, 2025 | 1 year ago |
| MACD: Buy Signal | Jul 9, 2025 | 1 year ago |
| MACD: Sell Signal | Jun 25, 2025 | 1 year ago |
| MACD: Buy Signal | Jun 24, 2025 | 1 year ago |
| MACD: Sell Signal | Jun 6, 2025 | 1 year ago |
| RSI: Overbought | May 28, 2025 | 1 year ago |
| RSI: Overbought | May 19, 2025 | 1 year ago |
| SMA: Bullish | Apr 30, 2025 | 1 year ago |
| MACD: Buy Signal | Apr 14, 2025 | 1 year ago |
| RSI: Oversold | Apr 7, 2025 | 1 year ago |
| RSI: Oversold | Mar 31, 2025 | 1 year ago |
| RSI: Oversold | Mar 26, 2025 | 1 year ago |
| RSI: Oversold | Mar 21, 2025 | 1 year ago |
| MACD: Sell Signal | Mar 14, 2025 | 1 year ago |
| MACD: Buy Signal | Feb 14, 2025 | 1 year ago |
| MACD: Sell Signal | Feb 12, 2025 | 1 year ago |
| RSI: Oversold | Jan 10, 2025 | 1 year ago |
Key statistics
- Market cap
- 1.23B
- Enterprise value
- 863.54M
- Trailing P/E
- 0.00
- Forward P/E
- -51.97
- PEG ratio
- 0.00
- Price / sales
- 1997.58
- Price / book
- 24.26
- EPS (TTM)
- -1.29
- Beta
- 1.45
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Profit margin
- 0.00%
- Revenue (TTM)
- 615.00K
- Revenue growth
- 0.00%
- Free cash flow
- -23.57M
- Total cash
- 72.05M
- Total debt
- 112.00K
- Return on equity
- -90.41%
- Shares outstanding
- 62.20M
- Short % of float
- 5.78%
- 50-day average
- 13.35
- 200-day average
- 8.99
Analyst view
Consensus: hold
Hold
Price target (mean) 19.75 0.0% upside
Now 19.75
- Target (low)
- 19.00
- Target (mean)
- 19.75
- Target (high)
- 20.00
Ratings (0m) 5 1 buy · 4 hold · 0 sell
- Strong buy0
- Buy1
- Hold4
- Sell0
- Strong sell0
Next earnings
Nov 5, 2026
Expected Nov 5, 2026. Consensus EPS estimate -0.09.
Financials — quick view
SLN Revenue — quarterly 0
SLN Net income — quarterly -12.27M
SLN EPS — quarterly -0.27
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Nov 5, 2026 | Sep 30, 2026 | -0.11289 | — | — | — |
| Aug 10, 2026 | Jun 30, 2026 | -0.13866 | -0.26 | -0.12 | -87.51% |
| May 7, 2026 | Mar 31, 2026 | -0.33 | -0.32 | +0.01 | +3.03% |
| Mar 5, 2026 | Dec 31, 2025 | -0.32 | -0.25 | +0.07 | +21.88% |
| Nov 6, 2025 | Sep 30, 2025 | -0.40 | -0.45 | -0.05 | -12.50% |
| Aug 7, 2025 | Jun 30, 2025 | -0.27 | -0.54 | -0.27 | -100.00% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Oct 21, 2026 | HC Wainwright & Co. | down | Buy | Neutral |
| Aug 11, 2026 | Morgan Stanley | main | Overweight | Overweight |
| Jun 24, 2026 | Cantor Fitzgerald | init | — | Overweight |
| Jun 17, 2026 | HC Wainwright & Co. | reit | Buy | Buy |
| Mar 13, 2026 | HC Wainwright & Co. | reit | Buy | Buy |
| Sep 16, 2025 | HC Wainwright & Co. | reit | Buy | Buy |
About Silence Therapeutics plc
Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN365 for hypercholesterolemia; and SLN098 for obesity. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc was incorporated in 1994 and is headquartered in London, United Kingdom.
- Sector
- Healthcare
- Industry
- Biotechnology
- Country
- United Kingdom
- Website
- silence-therapeutics.com
News
- Silence Therapeutics Investor Alert: Kahn Swick & Foti, LLC Investigates Adequacy of Price and Process in Proposed Sale of Silence Therapeutics plc - SLN
- HC Wainwright & Co. Downgrades Silence Therapeutics to Neutral, Lowers Price Target to $20
- Are BRZE, SLN, OPCH, RXO Obtaining Fair Deals for their Shareholders?
- Does Silence Therapeutics (SLN) Have the Potential to Rally 82.84% as Wall Street Analysts Expect?
- BRODSKY & SMITH SHAREHOLDER UPDATE: Notifying Investors of the Following Investigations: Silence Therapeutics plc (Nasdaq – SLN), Option Care Health, Inc. (Nasdaq – OPCH), RXO Inc. (NYSE – RXO), Sangoma Technologies Corporation (Nasdaq – SANG)
- Nasdaq Jumps Over 1% As Tech Stocks Gain: Investor Sentiment Improves, Greed Index Remains In ‘Extreme Fear’ Zone
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- Crude Oil Moves Higher; US Homebuilder Sentiment Falls In October
- 12 Health Care Stocks Moving In Monday's Intraday Session
- Why Is Silence Therapeutics Stock Skyrocketing Monday?
Your note
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Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| Siren, L.L.C. | 5.50% | 3,311,438 | 65.40M | Jun 29, 2026 |
| TCG Crossover Management, LLC | 5.04% | 3,033,560 | 59.91M | Jun 29, 2026 |
| Redmile Group, LLC | 3.60% | 2,164,777 | 42.75M | Jun 29, 2026 |
| Nantahala Capital Management, LLC | 2.24% | 1,346,731 | 26.60M | Jun 29, 2026 |
| Citadel Advisors Llc | 2.21% | 1,329,625 | 26.26M | Jun 29, 2026 |
| Nextech Invest, Ltd. | 1.58% | 952,400 | 18.81M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| Fidelity Select Portfolios-Select Biotechnology Portfolio | 3.39% | 2,042,900 | 40.35M | Aug 30, 2026 |
| Fidelity Advisor Series VII-Fidelity Advisor Biotechnology Fund | 0.88% | 531,788 | 10.50M | Aug 30, 2026 |
| Fidelity Select Portfolios-Select Health Care Portfolio | 0.83% | 500,000 | 9.88M | Aug 30, 2026 |
| iShares Trust-iShares Biotechnology ETF | 0.48% | 289,972 | 5.73M | Sep 29, 2026 |
| Fidelity Advisor Series VII-Fidelity Advisor Health Care Fund | 0.38% | 228,000 | 4.50M | Aug 30, 2026 |
| ALGER FUNDS-Alger Small Cap Growth Fund | 0.18% | 105,679 | 2.09M | Jul 30, 2026 |