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Iovance Biotherapeutics, Inc. IOVA

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7.97 USD -0.21 (-2.51%)

Nov 10, 2026, 2:25 PM EST

7.95 Day range 8.44
2.08 52-week range 15.37
YTD
+191.76%
1 year
+236.08%
Market cap
3.69B
Revenue (ttm)
378.98M
Profit margin
-58.19%
EPS (ttm)
-0.49
Shares out
462.66M
Forward P/E
-53.09
YTD return
+191.76%
1-year return
+236.08%
Volume
6.14M
Avg volume
16.33M
Open
8.04
Previous close
8.17
Day's range
7.95 – 8.44
52-week range
2.08 – 15.37
Beta
0.84
Analysts
Buy
Price target
14.50 (+82.0%)
Earnings date
Feb 23, 2027

5D -0.85 (-9.62%)

88.509WedThuFriMonTue7.99

Key statistics

Enterprise value
3.39B
PEG ratio
0.00
Price / sales
9.97
Price / book
4.65
Dividend yield
0.00%
Payout ratio
0.00%
Revenue growth
80.10%
Free cash flow
-139.86M
Total cash
376.32M
Total debt
45.21M
Return on equity
-29.12%
Short % of float
13.60%
50-day average
11.38
200-day average
5.98

Financials — quick view

All financials
IOVA Revenue — quarterly 121.47M
2022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 20262026-Q3 2026
IOVA Net income — quarterly -22.27M
2022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 20262026-Q3 2026
IOVA EPS — quarterly -0.05
2022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 20262026-Q3 2026

Earnings

IOVA recent earnings
Report dateQuarter endingEPS estimateEPS reportedSurpriseSurprise %
Feb 23, 2027Dec 30, 2026-0.09———
Nov 5, 2026Sep 30, 2026-0.08409-0.05+0.03+40.54%
Aug 6, 2026Jun 30, 2026-0.13346-0.11+0.02+17.58%
May 7, 2026Mar 31, 2026-0.19-0.190.000.00%
Feb 24, 2026Dec 31, 2025-0.22-0.18+0.04+18.18%
Nov 6, 2025Sep 30, 2025-0.29-0.25+0.04+13.79%

Upgrades / downgrades

IOVA analyst upgrades and downgrades
DateFirmActionFromTo
Nov 6, 2026BarclaysmainOverweightOverweight
Nov 6, 2026CitizensmainMarket OutperformMarket Outperform
Nov 3, 2026UBSmainNeutralNeutral
Oct 13, 2026BarclaysmainOverweightOverweight
Oct 8, 2026BairdmainNeutralNeutral
Sep 30, 2026Wells FargomainOverweightOverweight

About Iovance Biotherapeutics, Inc.

Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationally. The company offers Amtagvi, an individualized T cell therapy for solid tumor cancer and for the treatment of adult patients with previously treated advanced, or unresectable or metastatic melanomal; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic melanoma and metastatic renal cell carcinoma. It also develops lifileucel for the treatment of melanoma, cervical cancer, non-small cell lung cancer (NSCLC), endometrial cancer, and head and neck squamous cell carcinoma (HNSCC); LN-145-S1 to treat melanoma and HNSCC; LN-145 Gen 3 and core biopsy for the treatment of NSCLC; LN-145 Gen 3 to treat melanoma and HNSCC; IOV-2001 to treat chronic lymphocytic leukemia and small lymphocytic lymphoma; IOV-4001 for the treatment of melanoma and NSCLC; and IOV-3001 for use in the TIL therapy treatment regimen. The company has collaborations and licensing agreements with National Institutes of Health; the National Cancer Institute; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in Philadelphia, Pennsylvania.

Sector
Healthcare
Industry
Biotechnology
Country
United States
Website
iovance.com

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Insider holders

IOVA insider holders
InsiderRelationLatest transactionDateShares held
BELLEMIN JEAN-MARCChief Financial OfficerConversion of Exercise of derivative securityJun 1, 202560,529
BILINSKY IGOR PChief Operating OfficerConversion of Exercise of derivative securitySep 7, 2026142,074
GRAF FINCKENSTEIN FRIEDRICHOfficerConversion of Exercise of derivative securityJun 4, 2026140,111
KIRBY DANIEL GORDONOfficerConversion of Exercise of derivative securityAug 9, 2026154,511
MAYNARD RYAN DDirectorSaleNov 11, 20247,500
PURI RAJ KOfficerConversion of Exercise of derivative securitySep 7, 2026256,364

Institution ownership

IOVA institution ownership
Holder% heldSharesValueReported
Blackrock Inc.8.16%36,957,681301.94MJun 29, 2026
MHR Fund Management, LLC6.39%28,967,103236.66MJun 29, 2026
State Street Corporation5.40%24,478,268199.99MJun 29, 2026
Two Sigma Investments, LP4.20%19,010,697155.32MJun 29, 2026
Vanguard Capital Management LLC4.02%18,204,248148.73MJun 29, 2026
Vanguard Portfolio Management LLC3.18%14,388,999117.56MJun 29, 2026

Fund ownership

IOVA fund ownership
Holder% heldSharesValueReported
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund2.98%13,485,679110.18MJun 29, 2026
SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF2.48%11,251,09391.92MSep 29, 2026
iShares Trust-iShares Russell 2000 ETF2.27%10,291,73284.08MSep 29, 2026
VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund1.07%4,858,23139.69MJun 29, 2026
Fidelity Salem Street Trust-Fidelity Small Cap Index Fund0.96%4,357,35135.60MAug 30, 2026
VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund0.95%4,305,07835.17MJun 29, 2026