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Bicycle Therapeutics plc BCYC

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3.71 USD +0.04 (+1.09%)

Nov 4, 2026, 1:54 PM EST

3.65 Day range 3.80
3.33 52-week range 7.83
YTD
-47.60%
1 year
-46.00%

Financial health

Altman Z-Score

0.35 Distress zone

Bankruptcy-risk model: below 1.81 distress, above 2.99 safe.

Piotroski F-Score

2 / 9 Weak

Nine pass/fail tests of profitability, leverage and efficiency.

FMP rating

C+2 / 5 overall

  • DCF 1
  • Return on Equity 1
  • Return on Assets 1
  • Debt / Equity 4
  • P/E 1
  • P/B 5

Valuation

P/E -2.2×
FY 2016: -15.8×FY 2017: -9.8×FY 2018: -7.3×FY 2019: -3.4×FY 2020: -6.7×FY 2021: -22.8×FY 2022: -7.8×FY 2023: -3.6×FY 2024: -4.8×FY 2025: -2.2×
FY 2016 5y median -4.8× FY 2025
P/S 6.8×
FY 2016: 0.0×FY 2017: 77.4×FY 2018: 22.4×FY 2019: 7.5×FY 2020: 33.1×FY 2021: 130×FY 2022: 60.7×FY 2023: 23.9×FY 2024: 23.1×FY 2025: 6.8×
FY 2016 5y median 23.9× FY 2025
P/B 0.8×
FY 2016: 26.5×FY 2017: -3.4×FY 2018: -2.3×FY 2019: 1.1×FY 2020: 3.6×FY 2021: 4.4×FY 2022: 3.2×FY 2023: 1.7×FY 2024: 1.0×FY 2025: 0.8×
FY 2016 5y median 1.7× FY 2025
P/FCF -1.9×
FY 2016: -18.4×FY 2017: -63.1×FY 2018: -5.9×FY 2019: -3.5×FY 2020: -18.1×FY 2021: -90.7×FY 2022: -8.4×FY 2023: -10.1×FY 2024: -4.9×FY 2025: -1.9×
FY 2016 5y median -8.4× FY 2025
EV/EBITDA 0.6×
FY 2016: -15.3×FY 2017: -5.8×FY 2018: -4.5×FY 2019: -0.5×FY 2020: -4.4×FY 2021: -17.6×FY 2022: -5.4×FY 2023: -1.0×FY 2024: 0.3×FY 2025: 0.6×
FY 2016 5y median -1.0× FY 2025
EV/Sales -1.7×
FY 2016: 0.0×FY 2017: 44.6×FY 2018: 13.5×FY 2019: 1.0×FY 2020: 21.5×FY 2021: 96.7×FY 2022: 40.3×FY 2023: 6.0×FY 2024: -1.6×FY 2025: -1.7×
FY 2016 5y median 6.0× FY 2025
FCF Yield -51.5%
FY 2016: -5.4%FY 2017: -1.6%FY 2018: -17.1%FY 2019: -29.0%FY 2020: -5.5%FY 2021: -1.1%FY 2022: -12.0%FY 2023: -9.9%FY 2024: -20.4%FY 2025: -51.5%
FY 2016 5y median -12.0% FY 2025

Profitability

Gross Margin 100.0%
FY 2016: 0.0%FY 2017: -476.0%FY 2018: -190.9%FY 2019: -85.1%FY 2020: -219.0%FY 2021: 100.0%FY 2022: 100.0%FY 2023: -480.1%FY 2024: -390.3%FY 2025: 100.0%
FY 2016 5y median 100.0% FY 2025
Operating Margin -341.3%
FY 2016: 0.0%FY 2017: -787.0%FY 2018: -304.7%FY 2019: -190.6%FY 2020: -500.1%FY 2021: -561.0%FY 2022: -806.6%FY 2023: -704.1%FY 2024: -595.0%FY 2025: -341.3%
FY 2016 5y median -595.0% FY 2025
Net Margin -301.7%
FY 2016: 0.0%FY 2017: -789.3%FY 2018: -306.1%FY 2019: -221.8%FY 2020: -491.0%FY 2021: -571.2%FY 2022: -779.3%FY 2023: -669.7%FY 2024: -479.2%FY 2025: -301.7%
FY 2016 5y median -571.2% FY 2025
ROE -35.9%
FY 2016: -168.4%FY 2017: 34.5%FY 2018: 31.3%FY 2019: -32.8%FY 2020: -53.4%FY 2021: -19.3%FY 2022: -41.6%FY 2023: -48.7%FY 2024: -21.3%FY 2025: -35.9%
FY 2016 5y median -35.9% FY 2025
ROIC -37.3%
FY 2016: -167.9%FY 2017: -25.1%FY 2018: -29.4%FY 2019: -25.6%FY 2020: -36.9%FY 2021: -14.4%FY 2022: -31.9%FY 2023: -35.8%FY 2024: -22.8%FY 2025: -37.3%
FY 2016 5y median -31.9% FY 2025
ROA -30.5%
FY 2016: -114.2%FY 2017: -22.0%FY 2018: -26.8%FY 2019: -27.8%FY 2020: -31.7%FY 2021: -13.9%FY 2022: -27.5%FY 2023: -30.3%FY 2024: -17.7%FY 2025: -30.5%
FY 2016 5y median -27.5% FY 2025

Growth (YoY)

Revenue 105.8%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 246.4%FY 2019: 93.4%FY 2020: -24.7%FY 2021: 12.6%FY 2022: 23.6%FY 2023: 86.5%FY 2024: 30.8%FY 2025: 105.8%
FY 2016 FY 2025
Operating Income -18.0%
FY 2016: 0.0%FY 2017: -20.2%FY 2018: -34.1%FY 2019: -20.9%FY 2020: -97.6%FY 2021: -26.3%FY 2022: -77.8%FY 2023: -62.8%FY 2024: -10.5%FY 2025: -18.0%
FY 2016 FY 2025
EPS (diluted) -9.0%
FY 2016: 0.0%FY 2017: -60.5%FY 2018: -34.4%FY 2019: -68.9%FY 2020: 4.0%FY 2021: -0.4%FY 2022: -42.3%FY 2023: -33.7%FY 2024: 42.9%FY 2025: -9.0%
FY 2016 FY 2025
Free Cash Flow -52.2%
FY 2016: 0.0%FY 2017: 78.0%FY 2018: -978.5%FY 2019: -10.7%FY 2020: 37.1%FY 2021: 11.4%FY 2022: -524.7%FY 2023: 39.5%FY 2024: -161.1%FY 2025: -52.2%
FY 2016 FY 2025

Financial Health

Current Ratio 12.0×
FY 2016: 3.0×FY 2017: 7.6×FY 2018: 8.6×FY 2019: 11.8×FY 2020: 6.7×FY 2021: 12.7×FY 2022: 6.9×FY 2023: 8.1×FY 2024: 13.8×FY 2025: 12.0×
FY 2016 5y median 12.0× FY 2025
Quick Ratio 12.0×
FY 2016: 3.0×FY 2017: 7.6×FY 2018: 8.6×FY 2019: 11.8×FY 2020: 6.7×FY 2021: 12.7×FY 2022: 6.9×FY 2023: 8.1×FY 2024: 13.8×FY 2025: 12.0×
FY 2016 5y median 12.0× FY 2025
Debt / Equity 0.0×
FY 2016: 0.0×FY 2017: 0.0×FY 2018: 0.0×FY 2019: 0.0×FY 2020: 0.2×FY 2021: 0.1×FY 2022: 0.2×FY 2023: 0.1×FY 2024: 0.0×FY 2025: 0.0×
FY 2016 5y median 0.1× FY 2025
Net Debt / EBITDA 2.9×
FY 2016: 0.7×FY 2017: 4.3×FY 2018: 2.9×FY 2019: 3.6×FY 2020: 2.4×FY 2021: 6.2×FY 2022: 2.8×FY 2023: 2.8×FY 2024: 5.3×FY 2025: 2.9×
FY 2016 5y median 2.9× FY 2025
Interest Coverage -1203×
FY 2016: 0.0×FY 2017: 0.0×FY 2018: 0.0×FY 2019: 0.0×FY 2020: -114×FY 2021: -22.0×FY 2022: -34.9×FY 2023: -58.2×FY 2024: -121×FY 2025: -1203×
FY 2016 5y median -58.2× FY 2025

Dividends

Dividend Yield 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025
Payout Ratio 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025

Annual · latest fiscal year ends 2025-12-31