Amylyx Pharmaceuticals, Inc. AMLX
At closeNov 3, 2026, 4:01 PM EST
After hours · Nov 3, 4:01 PM ET
- YTD
- +141.72%
- 1 year
- +114.71%
- Market cap
- 3.66B
- EPS (ttm)
- -1.41
- Shares out
- 125.51M
- Forward P/E
- -26.78
- YTD return
- +141.72%
- 1-year return
- +114.71%
- Volume
- 1.20M
- Avg volume
- 2.19M
- Open
- 28.52
- Previous close
- 28.04
- Day's range
- 28.21 – 29.46
- 52-week range
- 10.83 – 41.14
- Beta
- -0.08
- Analysts
- Strong Buy
- Price target
- 42.64 (+46.0%)
- Earnings date
- Nov 5, 2026
YTD +17.83 (+156.13%)
Key statistics
- Enterprise value
- 2.88B
- PEG ratio
- 0.00
- Price / sales
- 0.00
- Price / book
- 13.59
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Revenue growth
- 0.00%
- Free cash flow
- -77.32M
- Total cash
- 250.76M
- Total debt
- 5.25M
- Return on equity
- -74.73%
- Short % of float
- 13.22%
- 50-day average
- 30.68
- 200-day average
- 20.15
Analyst view
Consensus: strong buy
- Target (low)
- 20.00
- Target (mean)
- 42.64
- Target (high)
- 57.00
- Strong buy0
- Buy11
- Hold1
- Sell0
- Strong sell0
Next earnings
Nov 5, 2026
Expected Nov 5, 2026. Consensus EPS estimate -0.37176.
Financials — quick view
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Nov 5, 2026 | Sep 30, 2026 | -0.38099 | — | — | — |
| Aug 6, 2026 | Jun 30, 2026 | -0.3609 | -0.39 | -0.03 | -8.06% |
| May 7, 2026 | Mar 31, 2026 | -0.34 | -0.37 | -0.03 | -8.82% |
| Mar 3, 2026 | Dec 31, 2025 | -0.31 | -0.30 | +0.01 | +3.23% |
| Nov 6, 2025 | Sep 30, 2025 | -0.43 | -0.37 | +0.06 | +13.95% |
| Aug 7, 2025 | Jun 30, 2025 | -0.44 | -0.46 | -0.02 | -4.55% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Oct 15, 2026 | Citigroup | main | Buy | Buy |
| Aug 27, 2026 | Guggenheim | main | Buy | Buy |
| Aug 19, 2026 | Mizuho | main | Outperform | Outperform |
| Aug 19, 2026 | Guggenheim | main | Buy | Buy |
| Aug 19, 2026 | Baird | main | Outperform | Outperform |
| Aug 18, 2026 | HC Wainwright & Co. | main | Buy | Buy |
About Amylyx Pharmaceuticals, Inc.
Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.
- Sector
- Healthcare
- Industry
- Drug Manufacturers - Specialty & Generic
- Country
- United States
- Website
- amylyx.com
News
Amylyx Pharmaceuticals to Participate in Upcoming November Investor Conferences
Amylyx Pharmaceuticals to Report Third Quarter 2026 Financial Results on November 5, 2026 Citigroup Maintains Buy on Amylyx Pharmaceuticals, Raises Price Target to $39
11 Stocks Most Likely to See a Short Squeeze Rally Amylyx Pharma To Present Phase 3 Topline Data Highlighting Avexitide’s Efficacy And Safety At ObesityWeek 2026 Annual Meeting
Amylyx Pharmaceuticals to Present Topline Data from Phase 3 LUCIDITY Clinical Trial of Avexitide in Post-Bariatric Hypoglycemia at ObesityWeek® 2026 Annual Meeting
Amylyx Pharma Q2 2026 Earnings Call Transcript
Dyadic International (NASDAQ:DYAI) & Amylyx Pharmaceuticals (NASDAQ:AMLX) Critical Review
Amylyx's Avexitide Phase III Win Sets Up FDA Filing for PBH Treatment
10 Stocks With Massive Short Squeeze Potential
Your note
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Insider holders
| Insider | Relation | Latest transaction | Date | Shares held |
|---|---|---|---|---|
| BEDROSIAN CAMILLE L | Officer | Sale | Sep 9, 2026 | 278,064 |
| COHEN JOSHUA BARRY | Chief Executive Officer | Sale | Sep 9, 2026 | 3,613,120 |
| FIRESTONE KAREN M. | Director | Conversion of Exercise of derivative security | Aug 30, 2026 | 116,900 |
| FRATES JAMES MATTHEW | Chief Financial Officer | Sale | Sep 9, 2026 | 400,156 |
| KLEE JUSTIN B | Chief Executive Officer | Sale | Sep 9, 2026 | 3,613,060 |
| MAZZARIELLO GINA | Officer | Sale | Sep 9, 2026 | 190,838 |
Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| FMR, LLC | 15.01% | 16,727,909 | 488.45M | Jun 29, 2026 |
| Blackrock Inc. | 7.92% | 8,827,085 | 257.75M | Jun 29, 2026 |
| Perceptive Advisors Llc | 7.48% | 8,334,882 | 243.38M | Jun 29, 2026 |
| TCG Crossover Management, LLC | 5.60% | 6,243,812 | 182.32M | Jun 29, 2026 |
| Commodore Capital Lp | 5.07% | 5,650,000 | 164.98M | Jun 29, 2026 |
| Jupiter Topco LLC | 4.70% | 5,236,102 | 152.89M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 2.83% | 3,154,723 | 92.12M | Jun 29, 2026 |
| iShares Trust-iShares Russell 2000 ETF | 2.42% | 2,694,093 | 78.67M | Sep 29, 2026 |
| Fidelity Advisor Series VII-Fidelity Advisor Biotechnology Fund | 2.18% | 2,433,200 | 71.05M | Aug 30, 2026 |
| Fidelity Securities Fund-Fidelity Small Cap Growth Fund | 1.90% | 2,115,961 | 61.79M | Jul 30, 2026 |
| Fidelity Select Portfolios-Select Health Care Portfolio | 1.44% | 1,600,000 | 46.72M | Aug 30, 2026 |
| Fidelity Capital Trust-Fidelity Stock Selector Small Cap Fund | 1.33% | 1,476,800 | 43.12M | Aug 30, 2026 |
