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AMLX

Amylyx Pharmaceuticals, Inc.

Healthcare · USD

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Price alert · AMLX

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28.86 USD +0.18 +0.63%
As of Oct 30, 2026 Extended hours 28.86 0.00%
Bid
28.85 × 2
Ask
28.86 × 2
28.00 Day range 29.09
11.38 52-week range 39.66
YTD
+138.91%
1 year
+105.41%
Open
28.41
Prev close
28.68
Mkt cap
3.62B
Vol
989.52K
Avg vol
2.21M
EPS
-1.41
P/E
0.00
Div yield
0.00%
More statistics
Low
28.00
High
29.09
Forward P/E
-26.47
Beta
-0.09
Short ratio
9.49
Inst. own
94.37%
Dividend
0.00
Ex-div date
Earnings
Nov 5, 2026
50-d avg
31.11
200-d avg
20.00
1y target
43.00

5D chart

Chart tools
Interval
AMLX five-day price chart26.227.027.728.429.1Oct 23Oct 27Oct 28Oct 29

Key statistics

Market cap
3.62B
Enterprise value
2.95B
Trailing P/E
0.00
Forward P/E
-26.47
PEG ratio
0.00
Price / sales
0.00
Price / book
13.44
EPS (TTM)
-1.41
Beta
-0.09
Dividend yield
0.00%
Payout ratio
0.00%
Profit margin
0.00%
Revenue (TTM)
0
Revenue growth
0.00%
Free cash flow
-77.32M
Total cash
250.76M
Total debt
5.25M
Return on equity
-74.73%
Shares outstanding
125.51M
Short % of float
13.22%
50-day average
31.11
200-day average
20.00

Analyst view

Consensus: none

Price target (mean) 43.00 +49.0% upside
Target (low)
20.00
Target (mean)
43.00
Target (high)
57.00
Ratings (0m) 12 11 buy · 1 hold · 0 sell
  • Strong buy0
  • Buy11
  • Hold1
  • Sell0
  • Strong sell0

Next earnings

Nov 5, 2026

Expected Nov 5, 2026. Consensus EPS estimate -0.37176.

Earnings history

Financials — quick view

All financials
AMLX Revenue — quarterly 0
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
AMLX Net income — quarterly -43.42M
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
AMLX EPS — quarterly -0.39
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026

Earnings

AMLX recent earnings
Report dateQuarter endingEPS estimateEPS reportedSurpriseSurprise %
Nov 5, 2026Sep 30, 2026-0.38099———
Aug 6, 2026Jun 30, 2026-0.3609-0.39-0.03-8.06%
May 7, 2026Mar 31, 2026-0.34-0.37-0.03-8.82%
Mar 3, 2026Dec 31, 2025-0.31-0.30+0.01+3.23%
Nov 6, 2025Sep 30, 2025-0.43-0.37+0.06+13.95%
Aug 7, 2025Jun 30, 2025-0.44-0.46-0.02-4.55%

Upgrades / downgrades

AMLX analyst upgrades and downgrades
DateFirmActionFromTo
Oct 15, 2026CitigroupmainBuyBuy
Aug 27, 2026GuggenheimmainBuyBuy
Aug 19, 2026MizuhomainOutperformOutperform
Aug 19, 2026GuggenheimmainBuyBuy
Aug 19, 2026BairdmainOutperformOutperform
Aug 18, 2026HC Wainwright & Co.mainBuyBuy

About Amylyx Pharmaceuticals, Inc.

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

Sector
Healthcare
Industry
Drug Manufacturers - Specialty & Generic
Country
United States
Website
amylyx.com

News

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Insider holders

AMLX insider holders
InsiderRelationLatest transactionDateShares held
BEDROSIAN CAMILLE LOfficerSaleSep 9, 2026278,064
COHEN JOSHUA BARRYChief Executive OfficerSaleSep 9, 20263,613,120
FIRESTONE KAREN M.DirectorConversion of Exercise of derivative securityAug 30, 2026116,900
FRATES JAMES MATTHEWChief Financial OfficerSaleSep 9, 2026400,156
KLEE JUSTIN BChief Executive OfficerSaleSep 9, 20263,613,060
MAZZARIELLO GINAOfficerSaleSep 9, 2026190,838

Institution ownership

AMLX institution ownership
Holder% heldSharesValueReported
FMR, LLC15.01%16,727,909482.77MJun 29, 2026
Blackrock Inc.7.92%8,827,085254.75MJun 29, 2026
Perceptive Advisors Llc7.48%8,334,882240.54MJun 29, 2026
TCG Crossover Management, LLC5.60%6,243,812180.20MJun 29, 2026
Commodore Capital Lp5.07%5,650,000163.06MJun 29, 2026
Jupiter Topco LLC4.70%5,236,102151.11MJun 29, 2026

Fund ownership

AMLX fund ownership
Holder% heldSharesValueReported
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund2.83%3,154,72391.05MJun 29, 2026
iShares Trust-iShares Russell 2000 ETF2.42%2,694,09377.75MSep 29, 2026
Fidelity Advisor Series VII-Fidelity Advisor Biotechnology Fund2.18%2,433,20070.22MAug 30, 2026
Fidelity Securities Fund-Fidelity Small Cap Growth Fund1.90%2,115,96161.07MJul 30, 2026
Fidelity Select Portfolios-Select Health Care Portfolio1.44%1,600,00046.18MAug 30, 2026
Fidelity Select Portfolios-Select Biotechnology Portfolio1.32%1,470,11742.43MAug 30, 2026
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