AMLX
Amylyx Pharmaceuticals, Inc.
Set alert
- YTD
- +138.91%
- 1 year
- +105.41%
- Open
- 28.41
- Prev close
- 28.68
- Mkt cap
- 3.62B
- Vol
- 989.52K
- Avg vol
- 2.21M
- EPS
- -1.41
- P/E
- 0.00
- Div yield
- 0.00%
More statistics
- Low
- 28.00
- High
- 29.09
- Forward P/E
- -26.47
- Beta
- -0.09
- Short ratio
- 9.49
- Inst. own
- 94.37%
- Dividend
- 0.00
- Ex-div date
- Earnings
- Nov 5, 2026
- 50-d avg
- 31.11
- 200-d avg
- 20.00
- 1y target
- 43.00
Key statistics
- Market cap
- 3.62B
- Enterprise value
- 2.95B
- Trailing P/E
- 0.00
- Forward P/E
- -26.47
- PEG ratio
- 0.00
- Price / sales
- 0.00
- Price / book
- 13.44
- EPS (TTM)
- -1.41
- Beta
- -0.09
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Profit margin
- 0.00%
- Revenue (TTM)
- 0
- Revenue growth
- 0.00%
- Free cash flow
- -77.32M
- Total cash
- 250.76M
- Total debt
- 5.25M
- Return on equity
- -74.73%
- Shares outstanding
- 125.51M
- Short % of float
- 13.22%
- 50-day average
- 31.11
- 200-day average
- 20.00
Analyst view
Consensus: none
- Target (low)
- 20.00
- Target (mean)
- 43.00
- Target (high)
- 57.00
- Strong buy0
- Buy11
- Hold1
- Sell0
- Strong sell0
Next earnings
Nov 5, 2026
Expected Nov 5, 2026. Consensus EPS estimate -0.37176.
Financials — quick view
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Nov 5, 2026 | Sep 30, 2026 | -0.38099 | — | — | — |
| Aug 6, 2026 | Jun 30, 2026 | -0.3609 | -0.39 | -0.03 | -8.06% |
| May 7, 2026 | Mar 31, 2026 | -0.34 | -0.37 | -0.03 | -8.82% |
| Mar 3, 2026 | Dec 31, 2025 | -0.31 | -0.30 | +0.01 | +3.23% |
| Nov 6, 2025 | Sep 30, 2025 | -0.43 | -0.37 | +0.06 | +13.95% |
| Aug 7, 2025 | Jun 30, 2025 | -0.44 | -0.46 | -0.02 | -4.55% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Oct 15, 2026 | Citigroup | main | Buy | Buy |
| Aug 27, 2026 | Guggenheim | main | Buy | Buy |
| Aug 19, 2026 | Mizuho | main | Outperform | Outperform |
| Aug 19, 2026 | Guggenheim | main | Buy | Buy |
| Aug 19, 2026 | Baird | main | Outperform | Outperform |
| Aug 18, 2026 | HC Wainwright & Co. | main | Buy | Buy |
About Amylyx Pharmaceuticals, Inc.
Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.
- Sector
- Healthcare
- Industry
- Drug Manufacturers - Specialty & Generic
- Country
- United States
- Website
- amylyx.com
News
- Citigroup Maintains Buy on Amylyx Pharmaceuticals, Raises Price Target to $39
- 11 Stocks Most Likely to See a Short Squeeze Rally
- Amylyx Pharma To Present Phase 3 Topline Data Highlighting Avexitide’s Efficacy And Safety At ObesityWeek 2026 Annual Meeting
- Amylyx Pharmaceuticals to Present Topline Data from Phase 3 LUCIDITY Clinical Trial of Avexitide in Post-Bariatric Hypoglycemia at ObesityWeek® 2026 Annual Meeting
- Amylyx Pharma Q2 2026 Earnings Call Transcript
- Dyadic International (NASDAQ:DYAI) & Amylyx Pharmaceuticals (NASDAQ:AMLX) Critical Review
- Amylyx's Avexitide Phase III Win Sets Up FDA Filing for PBH Treatment
- 10 Stocks With Massive Short Squeeze Potential
- Amylyx Pharmaceuticals, Inc. (AMLX) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript
- Better Healthcare ETF: Vanguard's VHT vs. State Street's Pharmaceuticals-Focused XPH
Your note
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Insider holders
| Insider | Relation | Latest transaction | Date | Shares held |
|---|---|---|---|---|
| BEDROSIAN CAMILLE L | Officer | Sale | Sep 9, 2026 | 278,064 |
| COHEN JOSHUA BARRY | Chief Executive Officer | Sale | Sep 9, 2026 | 3,613,120 |
| FIRESTONE KAREN M. | Director | Conversion of Exercise of derivative security | Aug 30, 2026 | 116,900 |
| FRATES JAMES MATTHEW | Chief Financial Officer | Sale | Sep 9, 2026 | 400,156 |
| KLEE JUSTIN B | Chief Executive Officer | Sale | Sep 9, 2026 | 3,613,060 |
| MAZZARIELLO GINA | Officer | Sale | Sep 9, 2026 | 190,838 |
Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| FMR, LLC | 15.01% | 16,727,909 | 482.77M | Jun 29, 2026 |
| Blackrock Inc. | 7.92% | 8,827,085 | 254.75M | Jun 29, 2026 |
| Perceptive Advisors Llc | 7.48% | 8,334,882 | 240.54M | Jun 29, 2026 |
| TCG Crossover Management, LLC | 5.60% | 6,243,812 | 180.20M | Jun 29, 2026 |
| Commodore Capital Lp | 5.07% | 5,650,000 | 163.06M | Jun 29, 2026 |
| Jupiter Topco LLC | 4.70% | 5,236,102 | 151.11M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 2.83% | 3,154,723 | 91.05M | Jun 29, 2026 |
| iShares Trust-iShares Russell 2000 ETF | 2.42% | 2,694,093 | 77.75M | Sep 29, 2026 |
| Fidelity Advisor Series VII-Fidelity Advisor Biotechnology Fund | 2.18% | 2,433,200 | 70.22M | Aug 30, 2026 |
| Fidelity Securities Fund-Fidelity Small Cap Growth Fund | 1.90% | 2,115,961 | 61.07M | Jul 30, 2026 |
| Fidelity Select Portfolios-Select Health Care Portfolio | 1.44% | 1,600,000 | 46.18M | Aug 30, 2026 |
| Fidelity Select Portfolios-Select Biotechnology Portfolio | 1.32% | 1,470,117 | 42.43M | Aug 30, 2026 |