Menu

Markets

Research

News

Learn

AI Chat
Get the app WatchlistsPortfoliosAlerts
Sign in

Alnylam Pharmaceuticals, Inc. ALNY

Full chart Compare
Set alert

Price alert · ALNY

All alert types
155.94 USD -0.72 (-0.46%)

At closeNov 6, 2026, 7:45 PM EST

155.42 -0.52 -0.33%

After hours · Nov 6, 7:45 PM ET

154.30 Day range 159.45
155.94 52-week range 473.29
YTD
-60.78%
1 year
-64.60%

Financial health

Altman Z-Score

3.70 Safe zone

Bankruptcy-risk model: below 1.81 distress, above 2.99 safe.

Piotroski F-Score

5 / 9 Average

Nine pass/fail tests of profitability, leverage and efficiency.

Rating

A-4 / 5 overall

  • DCF 4
  • Return on Equity 5
  • Return on Assets 5
  • Debt / Equity 2
  • P/E 3
  • P/B 1

Valuation

P/E 166×
FY 2016: -7.8×FY 2017: -23.4×FY 2018: -9.6×FY 2019: -14.2×FY 2020: -17.4×FY 2021: -23.6×FY 2022: -25.6×FY 2023: -54.4×FY 2024: -108×FY 2025: 166×
FY 2016 5y median -25.6× FY 2025
P/S 14.0×
FY 2016: 68.0×FY 2017: 128×FY 2018: 97.9×FY 2019: 57.3×FY 2020: 30.3×FY 2021: 23.8×FY 2022: 27.9×FY 2023: 13.1×FY 2024: 13.4×FY 2025: 14.0×
FY 2016 5y median 14.0× FY 2025
P/B 66.0×
FY 2016: 3.5×FY 2017: 6.5×FY 2018: 5.6×FY 2019: 8.7×FY 2020: 14.7×FY 2021: 34.1×FY 2022: -183×FY 2023: -108×FY 2024: 448×FY 2025: 66.0×
FY 2016 5y median 34.1× FY 2025
P/FCF 112×
FY 2016: -8.6×FY 2017: -23.6×FY 2018: -10.6×FY 2019: -30.1×FY 2020: -21.8×FY 2021: -28.0×FY 2022: -47.2×FY 2023: 570×FY 2024: -705×FY 2025: 112×
FY 2016 5y median -28.0× FY 2025
EV/EBITDA 81.9×
FY 2016: -7.7×FY 2017: -22.3×FY 2018: -9.2×FY 2019: -14.9×FY 2020: -21.5×FY 2021: -30.6×FY 2022: -31.7×FY 2023: -94.5×FY 2024: -170×FY 2025: 81.9×
FY 2016 5y median -31.7× FY 2025
EV/Sales 13.9×
FY 2016: 67.0×FY 2017: 121×FY 2018: 92.7×FY 2019: 56.2×FY 2020: 30.4×FY 2021: 24.0×FY 2022: 28.3×FY 2023: 13.3×FY 2024: 13.5×FY 2025: 13.9×
FY 2016 5y median 13.9× FY 2025
FCF Yield 0.9%
FY 2016: -11.6%FY 2017: -4.2%FY 2018: -9.4%FY 2019: -3.3%FY 2020: -4.6%FY 2021: -3.6%FY 2022: -2.1%FY 2023: 0.2%FY 2024: -0.1%FY 2025: 0.9%
FY 2016 5y median -0.1% FY 2025

Profitability

Gross Margin 81.8%
FY 2016: 100.0%FY 2017: 85.1%FY 2018: 97.6%FY 2019: 88.6%FY 2020: 84.2%FY 2021: 83.4%FY 2022: 83.7%FY 2023: 83.0%FY 2024: 85.6%FY 2025: 81.8%
FY 2016 5y median 83.4% FY 2025
Operating Margin 13.5%
FY 2016: -900.3%FY 2017: -556.2%FY 2018: -1087.6%FY 2019: -427.5%FY 2020: -168.1%FY 2021: -83.9%FY 2022: -75.7%FY 2023: -15.4%FY 2024: -7.9%FY 2025: 13.5%
FY 2016 5y median -15.4% FY 2025
Net Margin 8.4%
FY 2016: -869.6%FY 2017: -545.9%FY 2018: -1016.6%FY 2019: -403.2%FY 2020: -174.1%FY 2021: -101.0%FY 2022: -109.0%FY 2023: -24.1%FY 2024: -12.4%FY 2025: 8.4%
FY 2016 5y median -24.1% FY 2025
ROE 39.8%
FY 2016: -44.6%FY 2017: -27.8%FY 2018: -58.5%FY 2019: -61.6%FY 2020: -84.5%FY 2021: -145.0%FY 2022: 714.9%FY 2023: 199.5%FY 2024: -414.6%FY 2025: 39.8%
FY 2016 5y median 39.8% FY 2025
ROIC 13.7%
FY 2016: -37.5%FY 2017: -27.0%FY 2018: -58.4%FY 2019: -45.4%FY 2020: -29.0%FY 2021: -23.7%FY 2022: -27.8%FY 2023: -9.7%FY 2024: -4.2%FY 2025: 13.7%
FY 2016 5y median -9.7% FY 2025
ROA 6.3%
FY 2016: -32.5%FY 2017: -24.6%FY 2018: -48.4%FY 2019: -37.0%FY 2020: -25.2%FY 2021: -23.4%FY 2022: -31.9%FY 2023: -11.5%FY 2024: -6.6%FY 2025: 6.3%
FY 2016 5y median -11.5% FY 2025

Growth (YoY)

Revenue 65.2%
FY 2016: 14.8%FY 2017: 90.7%FY 2018: -16.7%FY 2019: 193.4%FY 2020: 124.3%FY 2021: 71.3%FY 2022: 22.9%FY 2023: 76.2%FY 2024: 23.0%FY 2025: 65.2%
FY 2016 FY 2025
Operating Income 383.6%
FY 2016: -43.4%FY 2017: -17.8%FY 2018: -62.9%FY 2019: -15.3%FY 2020: 11.8%FY 2021: 14.5%FY 2022: -10.8%FY 2023: 64.1%FY 2024: 37.3%FY 2025: 383.6%
FY 2016 FY 2025
EPS (diluted) 206.9%
FY 2016: -38.8%FY 2017: -13.2%FY 2018: -39.7%FY 2019: -7.1%FY 2020: 8.0%FY 2021: 3.5%FY 2022: -29.2%FY 2023: 62.2%FY 2024: 38.1%FY 2025: 206.9%
FY 2016 FY 2025
Free Cash Flow 1192.7%
FY 2016: -84.2%FY 2017: -30.8%FY 2018: -41.6%FY 2019: 39.3%FY 2020: -63.7%FY 2021: -4.8%FY 2022: 14.6%FY 2023: 106.8%FY 2024: -201.5%FY 2025: 1192.7%
FY 2016 FY 2025

Financial Health

Current Ratio 2.8×
FY 2016: 5.1×FY 2017: 12.2×FY 2018: 6.7×FY 2019: 4.9×FY 2020: 4.5×FY 2021: 4.0×FY 2022: 3.5×FY 2023: 3.1×FY 2024: 2.8×FY 2025: 2.8×
FY 2016 5y median 3.1× FY 2025
Quick Ratio 2.7×
FY 2016: 5.1×FY 2017: 12.2×FY 2018: 6.6×FY 2019: 4.7×FY 2020: 4.3×FY 2021: 3.9×FY 2022: 3.3×FY 2023: 3.0×FY 2024: 2.7×FY 2025: 2.7×
FY 2016 5y median 3.0× FY 2025
Debt / Equity 1.6×
FY 2016: 0.2×FY 2017: 0.0×FY 2018: 0.0×FY 2019: 0.2×FY 2020: 0.5×FY 2021: 1.7×FY 2022: -8.3×FY 2023: -5.9×FY 2024: 19.3×FY 2025: 1.6×
FY 2016 5y median 1.6× FY 2025
Net Debt / EBITDA -0.6×
FY 2016: 0.1×FY 2017: 1.3×FY 2018: 0.5×FY 2019: 0.3×FY 2020: -0.0×FY 2021: -0.3×FY 2022: -0.5×FY 2023: -1.9×FY 2024: -1.8×FY 2025: -0.6×
FY 2016 5y median -0.6× FY 2025
Interest Coverage 2.0×
FY 2016: 0.0×FY 2017: 0.0×FY 2018: 0.0×FY 2019: 0.0×FY 2020: -9.8×FY 2021: -5.0×FY 2022: -5.0×FY 2023: -2.3×FY 2024: -1.2×FY 2025: 2.0×
FY 2016 5y median -2.3× FY 2025

Dividends

Dividend Yield 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025
Payout Ratio 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025

Annual · latest fiscal year ends 2025-12-31