PTGX
Protagonist Therapeutics, Inc.
Set alert
- YTD
- +65.85%
- 1 year
- +86.06%
- Open
- 144.34
- Prev close
- 144.34
- Mkt cap
- 9.37B
- Vol
- 322.57K
- Avg vol
- 648.58K
- EPS
- 1.03
- P/E
- 140.63
- Div yield
- 0.00%
More statistics
- Low
- 142.54
- High
- 146.00
- Forward P/E
- -1459.30
- Beta
- 1.52
- Short ratio
- 12.29
- Inst. own
- 119.68%
- Dividend
- 0.00
- Ex-div date
- Earnings
- Nov 5, 2026
- 50-d avg
- 143.05
- 200-d avg
- 116.32
- 1y target
- 178.57
Key statistics
- Market cap
- 9.37B
- Enterprise value
- 8.57B
- Trailing P/E
- 140.63
- Forward P/E
- -1459.30
- PEG ratio
- 0.00
- Price / sales
- 33.24
- Price / book
- 11.13
- EPS (TTM)
- 1.03
- Beta
- 1.52
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Profit margin
- 29.40%
- Revenue (TTM)
- 281.99M
- Revenue growth
- 3749.20%
- Free cash flow
- 96.15M
- Total cash
- 782.58M
- Total debt
- 9.22M
- Return on equity
- 10.98%
- Shares outstanding
- 64.71M
- Short % of float
- 18.49%
- 50-day average
- 143.05
- 200-day average
- 116.32
Analyst view
Consensus: strong buy
- Target (low)
- 149.00
- Target (mean)
- 178.57
- Target (high)
- 225.00
- Strong buy3
- Buy11
- Hold0
- Sell0
- Strong sell0
Next earnings
Nov 5, 2026
Expected Nov 5, 2026. Consensus EPS estimate 2.66.
Financials — quick view
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Nov 5, 2026 | Sep 30, 2026 | 2.50 | — | — | — |
| Aug 5, 2026 | Jun 30, 2026 | 2.23 | 2.29 | +0.06 | +2.69% |
| May 5, 2026 | Mar 31, 2026 | -0.65 | 0.05 | +0.70 | +107.69% |
| Feb 25, 2026 | Dec 31, 2025 | -0.53 | -0.69 | -0.16 | -30.19% |
| Nov 6, 2025 | Sep 30, 2025 | -0.59 | -0.62 | -0.03 | -5.08% |
| Aug 6, 2025 | Jun 30, 2025 | -0.53 | -0.55 | -0.02 | -3.77% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Oct 21, 2026 | TD Cowen | main | Buy | Buy |
| Oct 12, 2026 | UBS | init | — | Buy |
| Sep 1, 2026 | Barclays | main | Overweight | Overweight |
| Sep 1, 2026 | BMO Capital | main | Outperform | Outperform |
| Aug 31, 2026 | Citigroup | main | Buy | Buy |
| Aug 31, 2026 | HC Wainwright & Co. | main | Buy | Buy |
About Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class oral peptide IL-17 antagonist, for the treatment of immune-mediated skin diseases in Phase 1 clinical trials; PN-477 and PN-458, which are development candidates for the treatment of obesity; PN-8047, an orally administered hepcidin functional mimetic small molecule; L-4R alpha antagonist for the treatment of atopic dermatitis and moderate-to-severe asthma; and amylinR-based oral and subcutaneous mono- and poly-agonists for the treatment of obesity. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.
- Sector
- Healthcare
- Industry
- Biotechnology
- Country
- United States
- Website
- protagonist-inc.com
News
- Protagonist Therapeutics (PTGX) to Report Q3 Results: Wall Street Expects Earnings Growth
- Why Protagonist Therapeutics (PTGX) is a Top Momentum Stock for the Long-Term
- Wall Street Analysts See a 25.34% Upside in Protagonist Therapeutics (PTGX): Can the Stock Really Move This High?
- Protagonist Therapeutics: The Opt-Out That Turned A Biotech Into A Royalty Compounder
- TD Cowen Maintains Buy on Protagonist Therapeutics, Raises Price Target to $160
- Analyzing Protagonist Therapeutics (NASDAQ:PTGX) and Sarepta Therapeutics (NASDAQ:SRPT)
- Head to Head Review: Genelux (NASDAQ:GNLX) versus Protagonist Therapeutics (NASDAQ:PTGX)
- Protagonist Therapeutics (PTGX) Upgraded to Strong Buy: Here's What You Should Know
- Here's How Much $100 Invested In Protagonist Therapeutics 10 Years Ago Would Be Worth Today
- UBS Initiates Coverage On Protagonist Therapeutics with Buy Rating, Announces Price Target of $184
Your note
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Insider holders
| Insider | Relation | Latest transaction | Date | Shares held |
|---|---|---|---|---|
| ALI ASIF | Chief Financial Officer | Sale | Apr 19, 2026 | 59,003 |
| GIRAUDO BRYAN M. | Director | Sale | May 7, 2026 | 0 |
| GUPTA SUNEEL | Officer | Conversion of Exercise of derivative security | Nov 25, 2024 | 267,433 |
| MOLINA ARTURO MD | Officer | Conversion of Exercise of derivative security | Mar 25, 2026 | 84,115 |
| O DOWD SARAH A | Director | Stock Award(Grant) | Jan 1, 2026 | 7,825 |
| PATEL DINESH V | Chief Executive Officer | Conversion of Exercise of derivative security | Sep 9, 2026 | 522,968 |
Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| Blackrock Inc. | 15.93% | 10,307,837 | 1.49B | Jun 29, 2026 |
| Farallon Capital Management LLC | 9.81% | 6,348,906 | 919.64M | Jun 29, 2026 |
| RTW Investments LP | 7.82% | 5,061,175 | 733.11M | Jun 29, 2026 |
| Vanguard Portfolio Management LLC | 5.61% | 3,629,298 | 525.70M | Jun 29, 2026 |
| Wellington Management Group, LLP | 5.28% | 3,416,781 | 494.92M | Jun 29, 2026 |
| UBS Group AG | 5.25% | 3,399,221 | 492.38M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| iShares Trust-iShares Core S&P Small-Cap ETF | 5.96% | 3,854,840 | 558.37M | Sep 29, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 3.16% | 2,044,938 | 296.21M | Jun 29, 2026 |
| iShares Trust-iShares Russell 2000 ETF | 2.46% | 1,594,175 | 230.92M | Sep 29, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Small-Cap Index Fund | 2.28% | 1,475,422 | 213.71M | Jun 29, 2026 |
| VANGUARD SPECIALIZED FUNDS-Vanguard Health Care Fund | 1.92% | 1,243,618 | 180.14M | Jul 30, 2026 |
| SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF | 1.57% | 1,013,552 | 146.81M | Sep 29, 2026 |