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State Street SPDR S&P Biotech ETF XBI

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154.97 USD +2.92 (+1.92%)

At closeNov 3, 2026, 7:51 PM EST

154.36 -0.61 -0.39%

After hours · Nov 3, 7:51 PM ET

152.83 Day range 156.92

106.30 52-week range 169.89

YTD: +27.10%
1 year: +41.06%

Issuer: SPDR
Asset class: Equity
Expense ratio: 0.35%
Assets under management: $10.51B
NAV: 152.05
Holdings: 165
Inception: 2006-01-31
Top 10 weight: 17.98%

MRNA MODERNA INC 2.36%
TWST TWIST BIOSCIENCE CORP 1.98%
NTRA NATERA INC 1.89%
HALO HALOZYME THERAPEUTICS INC 1.75%
BIIB BIOGEN INC 1.70%
AMGN AMGEN INC 1.69%
UTHR UNITED THERAPEUTICS CORP 1.68%
ABBV ABBVIE INC 1.66%
SYRE SPYRE THERAPEUTICS INC 1.63%
GILD GILEAD SCIENCES INC 1.63%
EXEL EXELIXIS INC 1.63%
TGTX TG THERAPEUTICS INC 1.52%
ORKA ORUKA THERAPEUTICS INC 1.52%
GRAL GRAIL INC 1.51%
VRTX VERTEX PHARMACEUTICALS INC 1.49%
REGN REGENERON PHARMACEUTICALS 1.45%
ALKS ALKERMES PLC 1.43%
CRSP CRISPR THERAPEUTICS AG 1.43%
PTGX PROTAGONIST THERAPEUTICS INC 1.42%
PTCT PTC THERAPEUTICS INC 1.37%
NBIX NEUROCRINE BIOSCIENCES INC 1.35%
KRYS KRYSTAL BIOTECH INC 1.34%
BBIO BRIDGEBIO PHARMA INC 1.33%
INCY INCYTE CORP 1.33%
RVMD REVOLUTION MEDICINES INC 1.31%

Healthcare 99.28%
Financial Services 0.72%

United States 96.65%
Switzerland 1.43%
United Kingdom 1.29%
Netherlands 0.50%
Ireland 0.08%
China 0.05%

Updated 2026-11-03

Funds holding XBI, by value held
Fund	Value held	Weight in fund
MKLOX	$25.24M	0.14%
BDYN	$11.43M	0.37%
EMPB	$5.37M	16.27%
TIH	$3.04M	0.49%
TSCV	$2.14M	1.14%
XNAV	$1.04M	3.63%
GEQ	$907.89K	0.45%
WLTG	$726.04K	0.96%
HFEQ	$296.35K	2.44%
HFND	$216.06K	0.60%
NSCS	$73.67K	0.85%
PSTR	$65.99K	0.10%
SECA	$50.18K	0.01%