Taysha Gene Therapies, Inc. TSHA

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Price alert · TSHA

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4.00 USD -0.13 -3.15%

At close · Nov 2

4.00 0.00 0.00%

After hours · Nov 2, 4:00 PM ET

Bid
3.98 × 2
Ask
3.99 × 2
3.95 Day range 4.20
3.46 52-week range 7.30
YTD
-27.27%
1 year
-19.35%
Open
4.30
Prev close
4.13
Mkt cap
1.30B
Vol
2.01M
Avg vol
3.54M
EPS
-0.40
P/E
0.00
Div yield
0.00%
More statistics
Low
3.95
High
4.20
Forward P/E
-8.65
Beta
1.31
Short ratio
10.79
Inst. own
94.28%
Dividend
0.00
Ex-div date
Earnings
Nov 3, 2026
50-d avg
4.82
200-d avg
5.32
1y target
13.00

2Y chart

Chart tools
Interval

Events in this range
  • Aug 12, 2025Earnings: -0.09; estimate -0.07; surprise -28.57%
  • Nov 4, 2025Earnings: -0.09; estimate -0.09; surprise 0%
  • Mar 19, 2026Earnings: -0.08; estimate -0.11; surprise 27.27%
  • May 6, 2026Earnings: -0.12; estimate -0.1; surprise -20%
  • Jun 23, 2026Rating: BMO Capital · Outperform → Outperform
  • Jun 30, 2026Rating: Baird · Outperform → Outperform
  • Jun 30, 2026Rating: Needham · Buy → Buy
  • Jul 2, 2026Rating: Citizens · Market Outperform → Market Outperform
  • Jul 21, 2026Rating: Goldman Sachs · Buy → Buy
  • Aug 11, 2026Earnings: -0.13; estimate -0.11327; surprise -14.77%
  • Sep 17, 2026Rating: Wolfe Research · — → Outperform
Signals (84)
NameDateAgo
MACD: Buy SignalOct 21, 20261 week ago
RSI: OversoldOct 12, 20263 weeks ago
RSI: OversoldOct 6, 20263 weeks ago
MACD: Sell SignalOct 2, 20261 month ago
MACD: Buy SignalSep 29, 20261 month ago
RSI: OversoldSep 25, 20261 month ago
SMA: BearishSep 9, 20261 month ago
SMA: BearishAug 26, 20262 months ago
SMA: BullishAug 25, 20262 months ago
MACD: Sell SignalAug 21, 20262 months ago
SMA: BearishAug 20, 20262 months ago
SMA: BullishAug 17, 20262 months ago
SMA: BearishAug 13, 20262 months ago
SMA: BullishAug 4, 20263 months ago
MACD: Buy SignalAug 3, 20263 months ago
SMA: BearishJul 16, 20263 months ago
SMA: BullishJul 15, 20263 months ago
SMA: BearishJul 13, 20263 months ago
MACD: Sell SignalJul 8, 20263 months ago
SMA: BullishJun 17, 20264 months ago

Newest 20 of 84.

Key statistics

Market cap
1.30B
Enterprise value
947.00M
Trailing P/E
0.00
Forward P/E
-8.65
PEG ratio
0.00
Price / sales
237.62
Price / book
3.36
EPS (TTM)
-0.41
Beta
1.31
Dividend yield
0.00%
Payout ratio
0.00%
Profit margin
0.00%
Revenue (TTM)
5.49M
Revenue growth
0.00%
Free cash flow
-80.97M
Total cash
455.41M
Total debt
56.71M
Return on equity
-47.05%
Shares outstanding
325.83M
Short % of float
15.98%
50-day average
4.82
200-day average
5.32

Financials — quick view

All financials
TSHA Revenue — quarterly 0
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
TSHA Net income — quarterly -46.64M
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
TSHA EPS — quarterly -0.13
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026

Earnings

TSHA recent earnings
Report dateQuarter endingEPS estimateEPS reportedSurpriseSurprise %
Nov 3, 2026Sep 30, 2026-0.12857———
Aug 11, 2026Jun 30, 2026-0.11327-0.13-0.02-14.77%
May 6, 2026Mar 31, 2026-0.10-0.12-0.02-20.00%
Mar 19, 2026Dec 31, 2025-0.11-0.08+0.03+27.27%
Nov 4, 2025Sep 30, 2025-0.09-0.090.000.00%
Aug 12, 2025Jun 30, 2025-0.07-0.09-0.02-28.57%

Upgrades / downgrades

TSHA analyst upgrades and downgrades
DateFirmActionFromTo
Sep 17, 2026Wolfe Researchinit—Outperform
Jul 21, 2026Goldman SachsmainBuyBuy
Jul 2, 2026CitizensreitMarket OutperformMarket Outperform
Jun 30, 2026NeedhammainBuyBuy
Jun 30, 2026BairdmainOutperformOutperform
Jun 23, 2026BMO CapitalmainOutperformOutperform

About Taysha Gene Therapies, Inc.

Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; and TSHA-114 for the treatment of fragile X syndrome. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.

Sector
Healthcare
Industry
Biotechnology
Country
United States

News

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Insider holders

TSHA insider holders
InsiderRelationLatest transactionDateShares held
ALAM KAMRANChief Financial OfficerSaleFeb 3, 20261,442,130
DONENBERG PHILLIP BRIANDirectorStock Award(Grant)May 31, 2026241,289
LONG ALISON SDirectorStock Award(Grant)May 31, 2026127,178
MANNING PAUL B.Beneficial Owner of more than 10% of a Class of SecurityPurchaseMay 29, 20250
NAGENDRAN SUKUMAROfficer and DirectorSaleJul 9, 2026936,410
NOLAN SEAN PATRICKChief Executive OfficerSaleJan 25, 20264,443,800

Institution ownership

TSHA institution ownership
Holder% heldSharesValueReported
Avoro Capital Advisors LLC7.33%23,888,88895.56MJun 29, 2026
RA Capital Management, L.P.7.23%23,555,64894.22MJun 29, 2026
Goldman Sachs Group Inc6.97%22,713,11890.85MJun 29, 2026
Blackrock Inc.6.35%20,691,92782.77MJun 29, 2026
Vestal Point Capital, LP5.96%19,415,00077.66MJun 29, 2026
Morgan Stanley5.06%16,487,47965.95MJun 29, 2026

Fund ownership

TSHA fund ownership
Holder% heldSharesValueReported
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund2.80%9,138,04336.55MJun 29, 2026
iShares Trust-iShares Russell 2000 ETF2.12%6,895,32527.58MSep 29, 2026
SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF1.58%5,138,80320.56MSep 29, 2026
Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund1.28%4,170,94816.68MAug 30, 2026
VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund0.93%3,044,55412.18MJun 29, 2026
Fidelity Salem Street Trust-Fidelity Small Cap Index Fund0.80%2,622,72410.49MJul 30, 2026