Taysha Gene Therapies, Inc. TSHA
At closeNov 13, 2026, 4:01 PM EST
After hours · Nov 13, 4:01 PM ET
- YTD
- -25.45%
- 1 year
- +2.24%
- Market cap
- 1.34B
- Revenue (ttm)
- 5.49M
- EPS (ttm)
- -0.41
- Shares out
- 325.83M
- Forward P/E
- -10.19
- YTD return
- -25.45%
- 1-year return
- +2.24%
- Volume
- 2.47M
- Avg volume
- 3.60M
- Open
- 4.24
- Previous close
- 4.21
- Day's range
- 3.98 – 4.33
- 52-week range
- 3.46 – 7.30
- Beta
- 1.31
- Analysts
- Strong Buy
- Price target
- 13.00 (+217.1%)
- Earnings date
- Mar 3, 2027
5D -0.10 (-2.33%)
Key statistics
- Enterprise value
- 995.87M
- PEG ratio
- 0.00
- Price / sales
- 243.56
- Price / book
- 4.73
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Revenue growth
- 0.00%
- Free cash flow
- -80.97M
- Total cash
- 455.41M
- Total debt
- 56.71M
- Return on equity
- -47.05%
- Short % of float
- 16.67%
- 50-day average
- 4.52
- 200-day average
- 5.30
Analyst view
Consensus: strong buy
- Target (low)
- 9.00
- Target (mean)
- 13.00
- Target (high)
- 19.00
- Strong buy3
- Buy10
- Hold0
- Sell0
- Strong sell0
Next earnings
Mar 3, 2027
Expected Mar 3, 2027. Consensus EPS estimate -0.10.
Financials — quick view
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Mar 3, 2027 | Dec 30, 2026 | -0.11233 | — | — | — |
| Nov 12, 2026 | Sep 30, 2026 | -0.12857 | -0.10 | +0.03 | +22.22% |
| Aug 11, 2026 | Jun 30, 2026 | -0.11327 | -0.13 | -0.02 | -14.77% |
| May 6, 2026 | Mar 31, 2026 | -0.10 | -0.12 | -0.02 | -20.00% |
| Mar 19, 2026 | Dec 31, 2025 | -0.11 | -0.08 | +0.03 | +27.27% |
| Nov 4, 2025 | Sep 30, 2025 | -0.09 | -0.09 | 0.00 | 0.00% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Sep 17, 2026 | Wolfe Research | init | — | Outperform |
| Jul 21, 2026 | Goldman Sachs | main | Buy | Buy |
| Jul 2, 2026 | Citizens | reit | Market Outperform | Market Outperform |
| Jun 30, 2026 | Needham | main | Buy | Buy |
| Jun 30, 2026 | Baird | main | Outperform | Outperform |
| Jun 23, 2026 | BMO Capital | main | Outperform | Outperform |
About Taysha Gene Therapies, Inc.
Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; and TSHA-114 for the treatment of fragile X syndrome. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.
- Sector
- Healthcare
- Industry
- Biotechnology
- Country
- United States
- Website
- tayshagtx.com
News
Taysha Gene Therapies, Inc. (TSHA) Q3 2026 Earnings Call Transcript 
Taysha Gene Therapies Q3 Earnings Call Highlights 
Taysha Gene Therapies Q3 2026 Earnings Call Transcript 
Taysha Gene Therapies Reports Third Quarter 2026 Financial Results and Provides Corporate Update 
Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) 
Taysha Gene Therapies to Release Third Quarter 2026 Financial Results and Host Conference Call and Webcast on November 12 
Taysha Gene Therapies (NASDAQ:TSHA) Hits New 52-Week Low – Time to Sell? 
Taysha Gene Therapies (NASDAQ:TSHA) versus MediWound (NASDAQ:MDWD) Head to Head Analysis 
Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) 
Taysha Gene Therapies Presents Multiple Encore Presentations For Its TSHA-102 Program At 55th Child Neurology Society Annual Meeting
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Insider holders
| Insider | Relation | Latest transaction | Date | Shares held |
|---|---|---|---|---|
| ALAM KAMRAN | Chief Financial Officer | Sale | Feb 3, 2026 | 1,442,130 |
| DONENBERG PHILLIP BRIAN | Director | Stock Award(Grant) | May 31, 2026 | 241,289 |
| LONG ALISON S | Director | Stock Award(Grant) | May 31, 2026 | 127,178 |
| MANNING PAUL B. | Beneficial Owner of more than 10% of a Class of Security | Purchase | May 29, 2025 | 0 |
| NAGENDRAN SUKUMAR | Officer and Director | Sale | Jul 9, 2026 | 936,410 |
| NOLAN SEAN PATRICK | Chief Executive Officer | Sale | Jan 25, 2026 | 4,443,800 |
Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | 7.33% | 23,888,888 | 97.94M | Jun 29, 2026 |
| RA Capital Management, L.P. | 7.23% | 23,555,648 | 96.58M | Jun 29, 2026 |
| Goldman Sachs Group Inc | 6.97% | 22,713,118 | 93.12M | Jun 29, 2026 |
| Blackrock Inc. | 6.35% | 20,691,927 | 84.84M | Jun 29, 2026 |
| Vestal Point Capital, LP | 5.96% | 19,415,000 | 79.60M | Jun 29, 2026 |
| Morgan Stanley | 5.06% | 16,487,479 | 67.60M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 2.80% | 9,138,043 | 37.47M | Jun 29, 2026 |
| iShares Trust-iShares Russell 2000 ETF | 2.12% | 6,895,325 | 28.27M | Sep 29, 2026 |
| SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF | 1.58% | 5,138,803 | 21.07M | Sep 29, 2026 |
| Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund | 1.28% | 4,170,948 | 17.10M | Sep 29, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund | 0.93% | 3,044,554 | 12.48M | Jun 29, 2026 |
| Fidelity Salem Street Trust-Fidelity Small Cap Index Fund | 0.81% | 2,626,937 | 10.77M | Aug 30, 2026 |