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Syndax Pharmaceuticals, Inc. SNDX

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10.45 USD -3.84 (-26.87%)

At closeNov 4, 2026, 7:36 PM EST

10.41 -0.04 -0.40%

After hours · Nov 4, 7:36 PM ET

10.00 Day range 14.69
10.00 52-week range 25.59
YTD
-50.26%
1 year
-31.92%

Financial health

Altman Z-Score

-1.63 Distress zone

Bankruptcy-risk model: below 1.81 distress, above 2.99 safe.

Piotroski F-Score

3 / 9 Weak

Nine pass/fail tests of profitability, leverage and efficiency.

FMP rating

C2 / 5 overall

  • DCF 1
  • Return on Equity 5
  • Return on Assets 1
  • Debt / Equity 1
  • P/E 1
  • P/B 1

Valuation

P/E -6.4×
FY 2016: -2.4×FY 2017: -3.0×FY 2018: -1.5×FY 2019: -4.8×FY 2020: -12.6×FY 2021: 45.6×FY 2022: -10.3×FY 2023: -7.3×FY 2024: -3.5×FY 2025: -6.4×
FY 2016 5y median -6.4× FY 2025
P/S 10.6×
FY 2016: 85.9×FY 2017: 87.3×FY 2018: 74.4×FY 2019: 176×FY 2020: 606×FY 2021: 8.2×FY 2022: 0.0×FY 2023: 0.0×FY 2024: 47.8×FY 2025: 10.6×
FY 2016 5y median 8.2× FY 2025
P/B 28.2×
FY 2016: 1.2×FY 2017: 1.8×FY 2018: 2.1×FY 2019: 8.5×FY 2020: 3.6×FY 2021: 2.8×FY 2022: 3.3×FY 2023: 2.7×FY 2024: 3.9×FY 2025: 28.2×
FY 2016 5y median 3.3× FY 2025
P/FCF -5.6×
FY 2016: -3.0×FY 2017: -3.9×FY 2018: -1.6×FY 2019: -5.3×FY 2020: -12.9×FY 2021: 39.3×FY 2022: -11.5×FY 2023: -9.5×FY 2024: -4.1×FY 2025: -5.6×
FY 2016 5y median -5.6× FY 2025
EV/EBITDA -8.1×
FY 2016: -1.9×FY 2017: -2.4×FY 2018: -1.1×FY 2019: -4.4×FY 2020: -11.7×FY 2021: 34.9×FY 2022: -10.1×FY 2023: -5.9×FY 2024: -4.2×FY 2025: -8.1×
FY 2016 5y median -5.9× FY 2025
EV/Sales 11.8×
FY 2016: 66.4×FY 2017: 70.6×FY 2018: 52.2×FY 2019: 161×FY 2020: 543×FY 2021: 6.7×FY 2022: 0.0×FY 2023: 0.0×FY 2024: 55.9×FY 2025: 11.8×
FY 2016 5y median 6.7× FY 2025
FCF Yield -17.8%
FY 2016: -33.8%FY 2017: -25.8%FY 2018: -60.9%FY 2019: -18.9%FY 2020: -7.8%FY 2021: 2.5%FY 2022: -8.7%FY 2023: -10.6%FY 2024: -24.3%FY 2025: -17.8%
FY 2016 5y median -10.6% FY 2025

Profitability

Gross Margin 96.0%
FY 2016: 100.0%FY 2017: 100.0%FY 2018: 100.0%FY 2019: 100.0%FY 2020: 100.0%FY 2021: 100.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 96.5%FY 2025: 96.0%
FY 2016 5y median 96.0% FY 2025
Operating Margin -158.4%
FY 2016: -3587.4%FY 2017: -2939.0%FY 2018: -5001.7%FY 2019: -3792.9%FY 2020: -4708.2%FY 2021: 18.8%FY 2022: 0.0%FY 2023: 0.0%FY 2024: -1434.4%FY 2025: -158.4%
FY 2016 5y median 0.0% FY 2025
Net Margin -165.6%
FY 2016: -3645.2%FY 2017: -2884.3%FY 2018: -4875.5%FY 2019: -3688.5%FY 2020: -4816.7%FY 2021: 17.8%FY 2022: 0.0%FY 2023: 0.0%FY 2024: -1346.1%FY 2025: -165.6%
FY 2016 5y median 0.0% FY 2025
ROE -441.6%
FY 2016: -52.9%FY 2017: -58.3%FY 2018: -139.4%FY 2019: -177.1%FY 2020: -29.0%FY 2021: 6.1%FY 2022: -31.9%FY 2023: -37.8%FY 2024: -110.6%FY 2025: -441.6%
FY 2016 5y median -37.8% FY 2025
ROIC -66.6%
FY 2016: -44.3%FY 2017: -51.0%FY 2018: -111.9%FY 2019: -126.1%FY 2020: -25.1%FY 2021: 6.1%FY 2022: -32.4%FY 2023: -41.4%FY 2024: -53.6%FY 2025: -66.6%
FY 2016 5y median -41.4% FY 2025
ROA -53.9%
FY 2016: -40.8%FY 2017: -44.3%FY 2018: -88.1%FY 2019: -88.1%FY 2020: -24.3%FY 2021: 5.5%FY 2022: -30.0%FY 2023: -34.2%FY 2024: -44.0%FY 2025: -53.9%
FY 2016 5y median -34.2% FY 2025

Growth (YoY)

Revenue 627.8%
FY 2016: 94.6%FY 2017: 72.8%FY 2018: -28.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 9109.6%FY 2022: -100.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 627.8%
FY 2016 FY 2025
Operating Income 19.6%
FY 2016: -113.4%FY 2017: -41.6%FY 2018: -22.5%FY 2019: 24.2%FY 2020: -24.1%FY 2021: 136.7%FY 2022: -678.8%FY 2023: -51.5%FY 2024: -47.7%FY 2025: 19.6%
FY 2016 FY 2025
EPS (diluted) 11.8%
FY 2016: 29.5%FY 2017: 4.6%FY 2018: -0.7%FY 2019: 37.0%FY 2020: 3.8%FY 2021: 127.1%FY 2022: -612.5%FY 2023: -21.1%FY 2024: -25.2%FY 2025: 11.8%
FY 2016 FY 2025
Free Cash Flow -17.6%
FY 2016: -1329.9%FY 2017: -34.0%FY 2018: -44.8%FY 2019: 26.3%FY 2020: -40.8%FY 2021: 140.7%FY 2022: -561.7%FY 2023: -19.9%FY 2024: -71.2%FY 2025: -17.6%
FY 2016 FY 2025

Financial Health

Current Ratio 4.4×
FY 2016: 10.5×FY 2017: 8.4×FY 2018: 5.2×FY 2019: 3.4×FY 2020: 15.8×FY 2021: 21.7×FY 2022: 16.9×FY 2023: 10.0×FY 2024: 5.8×FY 2025: 4.4×
FY 2016 5y median 10.0× FY 2025
Quick Ratio 4.1×
FY 2016: 10.2×FY 2017: 8.5×FY 2018: 5.1×FY 2019: 3.4×FY 2020: 15.8×FY 2021: 21.7×FY 2022: 16.9×FY 2023: 10.0×FY 2024: 5.8×FY 2025: 4.1×
FY 2016 5y median 10.0× FY 2025
Debt / Equity 5.4×
FY 2016: 0.0×FY 2017: 0.0×FY 2018: 0.0×FY 2019: 0.0×FY 2020: 0.1×FY 2021: 0.1×FY 2022: 0.0×FY 2023: 0.0×FY 2024: 1.2×FY 2025: 5.4×
FY 2016 5y median 0.1× FY 2025
Net Debt / EBITDA -0.8×
FY 2016: 0.5×FY 2017: 0.6×FY 2018: 0.5×FY 2019: 0.4×FY 2020: 1.3×FY 2021: -7.5×FY 2022: 0.5×FY 2023: 1.4×FY 2024: -0.6×FY 2025: -0.8×
FY 2016 5y median -0.6× FY 2025
Interest Coverage -8.1×
FY 2016: -45.8×FY 2017: -43.6×FY 2018: -39.1×FY 2019: 0.0×FY 2020: -30.3×FY 2021: 13.8×FY 2022: -48.4×FY 2023: -1106×FY 2024: -68.9×FY 2025: -8.1×
FY 2016 5y median -48.4× FY 2025

Dividends

Dividend Yield 0.0%
FY 2016: 2.5%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025
Payout Ratio 0.0%
FY 2016: -5.8%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025

Annual · latest fiscal year ends 2025-12-31