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Prime Medicine, Inc. PRME

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Price alert · PRME

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4.97 USD +0.42 (+9.23%)

At closeNov 5, 2026, 4:00 AM EST

4.92 -0.05 -1.01%

Pre-market · Nov 5, 4:00 AM ET

4.59 Day range 5.12
2.67 52-week range 5.91
YTD
+43.23%
1 year
+15.58%

Financial health

Altman Z-Score

-5.08 Distress zone

Bankruptcy-risk model: below 1.81 distress, above 2.99 safe.

Piotroski F-Score

2 / 9 Weak

Nine pass/fail tests of profitability, leverage and efficiency.

FMP rating

D+1 / 5 overall

  • DCF 1
  • Return on Equity 1
  • Return on Assets 1
  • Debt / Equity 1
  • P/E 1
  • P/B 1

Valuation

P/E -2.6×
FY 2019: -526×FY 2020: -291×FY 2021: -8.0×FY 2022: -12.7×FY 2023: -4.1×FY 2024: -1.8×FY 2025: -2.6×
FY 2019 5y median -4.1× FY 2025
P/S 111×
FY 2019: 0.0×FY 2020: 282×FY 2021: 0.0×FY 2022: 0.0×FY 2023: 0.0×FY 2024: 116×FY 2025: 111×
FY 2019 5y median 0.0× FY 2025
P/B 4.3×
FY 2019: 1059×FY 2020: 44.0×FY 2021: 6.1×FY 2022: 5.7×FY 2023: 6.1×FY 2024: 2.3×FY 2025: 4.3×
FY 2019 5y median 5.7× FY 2025
P/FCF -3.1×
FY 2019: -1103×FY 2020: -238×FY 2021: -38.5×FY 2022: -12.2×FY 2023: -4.6×FY 2024: -2.7×FY 2025: -3.1×
FY 2019 5y median -4.6× FY 2025
EV/EBITDA -2.9×
FY 2019: 367×FY 2020: -1613×FY 2021: -7.8×FY 2022: -13.7×FY 2023: -4.2×FY 2024: -1.1×FY 2025: -2.9×
FY 2019 5y median -4.2× FY 2025
EV/Sales 123×
FY 2019: 0.0×FY 2020: 275×FY 2021: 0.0×FY 2022: 0.0×FY 2023: 0.0×FY 2024: 68.6×FY 2025: 123×
FY 2019 5y median 0.0× FY 2025
FCF Yield -32.4%
FY 2019: -0.1%FY 2020: -0.4%FY 2021: -2.6%FY 2022: -8.2%FY 2023: -21.6%FY 2024: -37.6%FY 2025: -32.4%
FY 2019 5y median -21.6% FY 2025

Profitability

Gross Margin -58.1%
FY 2019: 0.0%FY 2020: 42.8%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 100.0%FY 2025: -58.1%
FY 2019 5y median 0.0% FY 2025
Operating Margin -4498.1%
FY 2019: 0.0%FY 2020: -17.9%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: -6787.4%FY 2025: -4498.1%
FY 2019 5y median 0.0% FY 2025
Net Margin -4342.4%
FY 2019: 0.0%FY 2020: -65.5%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: -6566.6%FY 2025: -4342.4%
FY 2019 5y median 0.0% FY 2025
ROE -166.4%
FY 2019: -182.1%FY 2020: -10.2%FY 2021: -69.0%FY 2022: -38.5%FY 2023: -148.9%FY 2024: -127.9%FY 2025: -166.4%
FY 2019 5y median -127.9% FY 2025
ROIC -66.5%
FY 2019: -156.4%FY 2020: -2.6%FY 2021: -33.5%FY 2022: -33.5%FY 2023: -139.4%FY 2024: -76.9%FY 2025: -66.5%
FY 2019 5y median -66.5% FY 2025
ROA -58.7%
FY 2019: -29.1%FY 2020: -6.2%FY 2021: -54.8%FY 2022: -33.8%FY 2023: -102.2%FY 2024: -65.8%FY 2025: -58.7%
FY 2019 5y median -58.7% FY 2025

Growth (YoY)

Revenue 55.3%
FY 2019: 0.0%FY 2020: 0.0%FY 2021: -100.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 55.3%
FY 2019 FY 2025
Operating Income -2.9%
FY 2019: 0.0%FY 2020: 57.1%FY 2021: -8963.7%FY 2022: -38.0%FY 2023: -75.7%FY 2024: 1.1%FY 2025: -2.9%
FY 2019 FY 2025
EPS (diluted) 18.3%
FY 2019: 0.0%FY 2020: -80.8%FY 2021: -3542.6%FY 2022: 24.0%FY 2023: -49.1%FY 2024: 24.2%FY 2025: 18.3%
FY 2019 FY 2025
Free Cash Flow -28.4%
FY 2019: 0.0%FY 2020: -363.5%FY 2021: -518.3%FY 2022: -286.9%FY 2023: -17.7%FY 2024: 25.3%FY 2025: -28.4%
FY 2019 FY 2025

Financial Health

Current Ratio 4.8×
FY 2019: 1.2×FY 2020: 2.7×FY 2021: 4.7×FY 2022: 11.1×FY 2023: 2.5×FY 2024: 5.6×FY 2025: 4.8×
FY 2019 5y median 4.8× FY 2025
Quick Ratio 4.8×
FY 2019: 1.2×FY 2020: 2.7×FY 2021: 4.7×FY 2022: 11.1×FY 2023: 2.5×FY 2024: 5.6×FY 2025: 4.8×
FY 2019 5y median 4.8× FY 2025
Debt / Equity 1.0×
FY 2019: 0.0×FY 2020: 0.0×FY 2021: 0.0×FY 2022: 0.1×FY 2023: 0.1×FY 2024: 0.3×FY 2025: 1.0×
FY 2019 5y median 0.1× FY 2025
Net Debt / EBITDA -0.3×
FY 2019: -2.2×FY 2020: 41.6×FY 2021: 1.1×FY 2022: 1.3×FY 2023: 0.1×FY 2024: 0.7×FY 2025: -0.3×
FY 2019 5y median 0.7× FY 2025
Interest Coverage 0.0×
FY 2019: 0.0×FY 2020: 0.0×FY 2021: 0.0×FY 2022: 0.0×FY 2023: 0.0×FY 2024: 0.0×FY 2025: 0.0×
FY 2019 5y median 0.0× FY 2025

Dividends

Dividend Yield 0.0%
FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2019 5y median 0.0% FY 2025
Payout Ratio 0.0%
FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2019 5y median 0.0% FY 2025

Annual · latest fiscal year ends 2025-12-31