Alto Neuroscience, Inc. ANRO

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22.70 USD +0.51 (+2.30%)

At closeNov 3, 2026, 4:01 PM EST

22.70 0.00 0.00%

After hours · Nov 3, 4:01 PM ET

22.40 Day range 23.14
10.20 52-week range 37.48
YTD
+27.53%
1 year
+86.52%
Market cap
890.80M
EPS (ttm)
-2.31
Shares out
39.24M
Forward P/E
-7.78
YTD return
+27.53%
1-year return
+86.52%
Volume
505.18K
Avg volume
564.53K
Open
22.71
Previous close
22.19
Day's range
22.40 – 23.14
52-week range
10.20 – 37.48
Beta
1.16
Analysts
Strong Buy
Price target
38.38 (+69.1%)
Earnings date
Nov 11, 2026

2Y +18.98 (+511.59%)

020Jan 25Jun 25Nov 25Mar 26Aug 2622.69

Key statistics

Enterprise value
822.62M
PEG ratio
0.00
Price / sales
0.00
Price / book
4.09
Dividend yield
0.00%
Payout ratio
0.00%
Revenue growth
0.00%
Free cash flow
-42.90M
Total cash
243.73M
Total debt
23.29M
Return on equity
-49.17%
Short % of float
12.46%
50-day average
31.01
200-day average
23.57

Financials — quick view

All financials
ANRO Revenue — quarterly 0
2022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
ANRO Net income — quarterly -27.64M
2022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
ANRO EPS — quarterly -0.65
2022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026

Earnings

ANRO recent earnings
Report dateQuarter endingEPS estimateEPS reportedSurpriseSurprise %
Nov 11, 2026Sep 30, 2026-0.67274———
Aug 12, 2026Jun 30, 2026-0.73454-0.65+0.08+11.51%
May 13, 2026Mar 31, 2026-0.56-0.80-0.24-42.86%
Mar 16, 2026Dec 31, 2025-0.56-0.45+0.11+19.64%
Nov 12, 2025Sep 30, 2025-0.66-0.52+0.14+21.21%
Aug 13, 2025Jun 30, 2025-0.57-0.65-0.08-14.04%

Upgrades / downgrades

ANRO analyst upgrades and downgrades
DateFirmActionFromTo
Aug 17, 2026HC Wainwright & Co.mainBuyBuy
Aug 13, 2026WedbushmainNeutralNeutral
Aug 13, 2026BTIGmainBuyBuy
May 18, 2026BairdmainOutperformOutperform
May 14, 2026WedbushmainNeutralNeutral
May 11, 2026HC Wainwright & Co.reitBuyBuy

About Alto Neuroscience, Inc.

Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. The company's product pipeline includes ALTO-100, which is in Phase 2b clinical trial for the treatment of patients with bipolar depression (BPD). It also develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties, which is in Phase 2b clinical trial to treat patients with major depressive disorder (MDD); ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor that is in Phase 2 proof-of-concept (POC) trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist, which is in Phase 2 POC trial to treat patients with MDD and higher levels of anhedonia; ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor that is in Phase 1 clinical trial for the treatment of MDD; and ALTO-208, a fixed-dose combination of pramipexole and aprepitant, an antiemetic, neurokinin-1 (NK-1) receptor antagonist for patients with Parkinson's disease for patients with Parkinson's disease. The company was incorporated in 2019 and is headquartered in Mountain View, California.

Sector
Healthcare
Industry
Biotechnology
Country
United States

News

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Insider holders

ANRO insider holders
InsiderRelationLatest transactionDateShares held
ETKIN AMITChief Executive OfficerStock GiftMay 13, 2026833,949

Institution ownership

ANRO institution ownership
Holder% heldSharesValueReported
Alpha Wave Global, LP9.45%3,707,75794.81MJun 29, 2026
Commodore Capital Lp6.94%2,723,19669.63MJun 29, 2026
Blackrock Inc.5.40%2,121,00954.23MJun 29, 2026
Perceptive Advisors Llc4.10%1,609,89341.16MJun 29, 2026
Adage Capital Partners GP L.L.C.4.08%1,600,00040.91MJun 29, 2026
Vanguard Capital Management LLC3.54%1,389,47735.53MJun 29, 2026

Fund ownership

ANRO fund ownership
Holder% heldSharesValueReported
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund2.58%1,011,88125.87MJun 29, 2026
iShares Trust-iShares Russell 2000 ETF1.69%662,26916.93MAug 30, 2026
Franklin Strategic Series-Franklin Biotechnology Discovery Fund0.89%347,9048.90MJul 30, 2026
VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund0.88%346,6188.86MJun 29, 2026
Fidelity Salem Street Trust-Fidelity Small Cap Index Fund0.73%287,0337.34MJul 30, 2026
iShares Trust-iShares Biotechnology ETF0.67%264,1956.76MAug 30, 2026