Amylyx Pharmaceuticals, Inc. AMLX
Nov 10, 2026, 12:14 PM EST
- YTD
- +148.76%
- 1 year
- +146.72%
- Market cap
- 3.87B
- EPS (ttm)
- -1.43
- Shares out
- 128.56M
- Forward P/E
- -28.11
- YTD return
- +148.76%
- 1-year return
- +146.72%
- Volume
- 689.18K
- Avg volume
- 2.12M
- Open
- 29.90
- Previous close
- 30.21
- Day's range
- 29.76 – 30.80
- 52-week range
- 10.83 – 41.14
- Beta
- -0.08
- Analysts
- Strong Buy
- Price target
- 42.91 (+42.8%)
- Earnings date
- Nov 5, 2026
5D +1.08 (+3.77%)
Key statistics
- Enterprise value
- 3.03B
- PEG ratio
- 0.00
- Price / sales
- 0.00
- Price / book
- 5.14
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Revenue growth
- 0.00%
- Free cash flow
- -80.52M
- Total cash
- 768.13M
- Total debt
- 4.94M
- Return on equity
- -30.06%
- Short % of float
- 12.83%
- 50-day average
- 30.00
- 200-day average
- 20.41
Analyst view
Consensus: strong buy
- Target (low)
- 25.00
- Target (mean)
- 42.91
- Target (high)
- 57.00
- Strong buy0
- Buy11
- Hold1
- Sell0
- Strong sell0
Next earnings
Nov 5, 2026
Expected Nov 5, 2026. Consensus EPS estimate -0.37493.
Financials — quick view
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Nov 5, 2026 | Sep 30, 2026 | -0.38099 | — | — | — |
| Aug 6, 2026 | Jun 30, 2026 | -0.3609 | -0.39 | -0.03 | -8.06% |
| May 7, 2026 | Mar 31, 2026 | -0.34 | -0.37 | -0.03 | -8.82% |
| Mar 3, 2026 | Dec 31, 2025 | -0.31 | -0.30 | +0.01 | +3.23% |
| Nov 6, 2025 | Sep 30, 2025 | -0.43 | -0.37 | +0.06 | +13.95% |
| Aug 7, 2025 | Jun 30, 2025 | -0.44 | -0.46 | -0.02 | -4.55% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Oct 15, 2026 | Citigroup | main | Buy | Buy |
| Aug 27, 2026 | Guggenheim | main | Buy | Buy |
| Aug 19, 2026 | Mizuho | main | Outperform | Outperform |
| Aug 19, 2026 | Guggenheim | main | Buy | Buy |
| Aug 19, 2026 | Baird | main | Outperform | Outperform |
| Aug 18, 2026 | HC Wainwright & Co. | main | Buy | Buy |
About Amylyx Pharmaceuticals, Inc.
Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.
- Sector
- Healthcare
- Industry
- Drug Manufacturers - Specialty & Generic
- Country
- United States
- Website
- amylyx.com
News
Amylyx Pharmaceuticals Q3 Earnings Call Highlights
Amylyx Pharmaceuticals, Inc. (AMLX) Q3 2026 Earnings Call Transcript
Amylyx Pharmaceuticals Q3 Earnings Call Highlights Amylyx Pharma Q3 EPS $(0.38), Inline
Amylyx Pharmaceuticals Reports Third Quarter 2026 Financial Results
Amylyx Pharmaceuticals to Host Investor Event at ObesityWeek® 2026 Featuring Leading PBH Experts
Amylyx Pharmaceuticals to Participate in Upcoming November Investor Conferences Citigroup Maintains Buy on Amylyx Pharmaceuticals, Raises Price Target to $39
Amylyx Pharma To Present Phase 3 Topline Data Highlighting Avexitide’s Efficacy And Safety At ObesityWeek 2026 Annual Meeting
Amylyx Pharma Q2 2026 Earnings Call Transcript
Your note
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Insider holders
| Insider | Relation | Latest transaction | Date | Shares held |
|---|---|---|---|---|
| BEDROSIAN CAMILLE L | Officer | Sale | Sep 9, 2026 | 278,064 |
| COHEN JOSHUA BARRY | Chief Executive Officer | Sale | Sep 9, 2026 | 3,613,120 |
| FIRESTONE KAREN M. | Director | Conversion of Exercise of derivative security | Aug 30, 2026 | 116,900 |
| FRATES JAMES MATTHEW | Chief Financial Officer | Sale | Sep 9, 2026 | 400,156 |
| KLEE JUSTIN B | Chief Executive Officer | Sale | Sep 9, 2026 | 3,613,060 |
| MAZZARIELLO GINA | Officer | Sale | Sep 9, 2026 | 190,838 |
Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| FMR, LLC | 15.01% | 16,727,909 | 504.51M | Jun 29, 2026 |
| Blackrock Inc. | 7.92% | 8,827,085 | 266.22M | Jun 29, 2026 |
| Perceptive Advisors Llc | 7.48% | 8,334,882 | 251.38M | Jun 29, 2026 |
| TCG Crossover Management, LLC | 5.60% | 6,243,812 | 188.31M | Jun 29, 2026 |
| Commodore Capital Lp | 5.07% | 5,650,000 | 170.40M | Jun 29, 2026 |
| Jupiter Topco LLC | 4.70% | 5,236,102 | 157.92M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 2.83% | 3,154,723 | 95.15M | Jun 29, 2026 |
| iShares Trust-iShares Russell 2000 ETF | 2.42% | 2,694,093 | 81.25M | Sep 29, 2026 |
| Fidelity Advisor Series VII-Fidelity Advisor Biotechnology Fund | 2.18% | 2,433,200 | 73.39M | Sep 29, 2026 |
| Fidelity Securities Fund-Fidelity Small Cap Growth Fund | 1.90% | 2,115,961 | 63.82M | Aug 30, 2026 |
| Fidelity Rutland Square TRT II-Strategic Advisers Fidelity U.S. Total | 1.52% | 1,695,959 | 51.15M | Sep 29, 2026 |
| Fidelity Select Portfolios-Select Biotechnology Portfolio | 1.44% | 1,601,402 | 48.30M | Sep 29, 2026 |
