Xeris Biopharma Holdings, Inc. XERS
At closeNov 5, 2026, 7:51 AM EST
Pre-market · Nov 5, 7:51 AM ET
- YTD
- +33.25%
- 1 year
- +5.66%
- Market cap
- 1.91B
- Revenue (ttm)
- 335.41M
- Profit margin
- -5.12%
- EPS (ttm)
- -0.10
- Shares out
- 182.32M
- Forward P/E
- 53.19
- YTD return
- +33.25%
- 1-year return
- +5.66%
- Volume
- 3.14M
- Avg volume
- 2.40M
- Open
- 10.52
- Previous close
- 10.35
- Day's range
- 10.15 – 10.71
- 52-week range
- 5.25 – 11.42
- Beta
- 0.84
- Price target
- 12.86 (+22.9%)
- Earnings date
- Nov 5, 2026
5m -0.44 (-4.04%)
Key statistics
- Enterprise value
- 2.05B
- PEG ratio
- 0.00
- Price / sales
- 5.69
- Price / book
- 0.00
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Revenue growth
- 28.70%
- Free cash flow
- 52.45M
- Total cash
- 121.75M
- Total debt
- 289.44M
- Return on equity
- 0.00%
- Short % of float
- 4.55%
- 50-day average
- 9.37
- 200-day average
- 7.53
Analyst view
- Target (low)
- 8.00
- Target (mean)
- 12.86
- Target (high)
- 18.00
- Strong buy1
- Buy5
- Hold1
- Sell0
- Strong sell0
Next earnings
Nov 5, 2026
Expected Nov 5, 2026. Consensus EPS estimate 0.02667.
Financials — quick view
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Nov 5, 2026 | Sep 30, 2026 | 0.03167 | — | — | — |
| Aug 6, 2026 | Jun 30, 2026 | 0.01214 | -0.18 | -0.19 | -1,582.70% |
| May 7, 2026 | Mar 31, 2026 | -0.00274 | 0.01 | +0.01 | +464.96% |
| Mar 2, 2026 | Dec 31, 2025 | 0.03 | 0.06 | +0.03 | +100.00% |
| Nov 6, 2025 | Sep 30, 2025 | 0.01 | 0.0035 | -0.01 | -65.00% |
| Aug 7, 2025 | Jun 30, 2025 | -0.03 | -0.01 | +0.02 | +66.67% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Oct 6, 2026 | Barclays | main | Overweight | Overweight |
| Sep 10, 2026 | Leerink Partners | main | Outperform | Outperform |
| Aug 20, 2026 | Barclays | main | Overweight | Overweight |
| Mar 2, 2026 | HC Wainwright & Co. | reit | Buy | Buy |
| Jan 9, 2026 | HC Wainwright & Co. | reit | Buy | Buy |
| Dec 9, 2025 | Barclays | init | — | Overweight |
About Xeris Biopharma Holdings, Inc.
Xeris Biopharma Holdings, Inc., a commercial-stage biopharmaceutical company, engages in developing and commercializing therapies for chronic endocrine and neurological diseases in Illinois. It offers Gvoke, a ready-to-use liquid-stable glucagon for the treatment of severe hypoglycemia in pediatric and adult patients; Keveyis, a therapy for the treatment of hyperkalemic, hypokalemic, and related variants of primary periodic paralysis; and Recorlev, a cortisol synthesis inhibitor for the treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome. It is also developing XP-8121, a once-weekly subcutaneous injection of levothyroxine that is in phase 3 clinical trial for the treatment of hypothyroidism. The company was incorporated in 2005 and is headquartered in Chicago, Illinois.
- Sector
- Healthcare
- Industry
- Drug Manufacturers - Specialty & Generic
- Country
- United States
- Website
- xerispharma.com
News
Xeris Biopharma Holdings FY2030 Revenue expected to be more than 1 Billion up from $750M 
Xeris Biopharma Holdings Raises FY2026 Sales Guidance from $385.000M-$390.000M to $395.000M-$405.000M vs $387.665M Est - Xeris Biopharma Holdings Q3 Adj. EPS $0.06 Beats $0.02 Estimate, Sales $106.267M Beat $101.517M Estimate
Xeris Biopharma (NASDAQ:XERS) vs. Cocrystal Pharma (NASDAQ:COCP) Head-To-Head Contrast 
Xeris Biopharma Welcomes Menassie M. Taddese to Board of Directors 
Xeris Biopharma Files Patent Infringement Lawsuits Related To Its KEYEVIS Product In U.S. District Court In New Jersey 
Barclays Maintains Overweight on Xeris Biopharma Holdings, Raises Price Target to $14 
Full Transcript: Xeris Biopharma Holdings Q2 2026 Earnings Call - Lundbeck Is Said To Express Interest In Buying Xeris Biopharma, Bloomberg Reports
TriSalus Life Sciences, Lakefront Biotherapeutics, Editas Medicine And Other Big Stocks Moving Higher On Wednesday
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Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| Blackrock Inc. | 7.97% | 14,525,539 | 151.94M | Jun 29, 2026 |
| Shaw D.E. & Co., Inc. | 4.28% | 7,804,758 | 81.64M | Jun 29, 2026 |
| Vanguard Capital Management LLC | 4.03% | 7,340,229 | 76.78M | Jun 29, 2026 |
| State Street Corporation | 2.64% | 4,821,566 | 50.43M | Jun 29, 2026 |
| Geode Capital Management, LLC | 2.59% | 4,718,183 | 49.35M | Jun 29, 2026 |
| Nuveen, LLC | 2.41% | 4,385,141 | 45.87M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 2.85% | 5,193,656 | 54.33M | Jun 29, 2026 |
| iShares Trust-iShares Russell 2000 ETF | 2.42% | 4,417,108 | 46.20M | Sep 29, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund | 1.09% | 1,986,461 | 20.78M | Jun 29, 2026 |
| College Retirement Equities Fd.-College Retirement Equities Fd. - Tota | 1.07% | 1,951,890 | 20.42M | Jun 29, 2026 |
| Fidelity Salem Street Trust-Fidelity Small Cap Index Fund | 1.03% | 1,872,201 | 19.58M | Aug 30, 2026 |
| iShares Trust-iShares Russell 2000 Growth ETF | 0.88% | 1,595,993 | 16.69M | Sep 29, 2026 |