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State Street SPDR S&P Biotech ETF XBI

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156.90 USD +4.69 (+3.08%)

At closeNov 10, 2026, 7:41 AM EST

156.90 0.00 0.00%

Pre-market · Nov 10, 7:41 AM ET

151.00 Day range 157.92

109.53 52-week range 169.89

YTD: +28.68%
1 year: +42.52%

Issuer: SPDR
Asset class: Equity
Expense ratio: 0.35%
Assets under management: $10.03B
NAV: 148.54
Holdings: 165
Inception: 2006-01-31
Top 10 weight: 18.42%

MRNA MODERNA INC 2.71%
EXEL EXELIXIS INC 1.80%
AMGN AMGEN INC 1.79%
BIIB BIOGEN INC 1.76%
GILD GILEAD SCIENCES INC 1.75%
ABBV ABBVIE INC 1.75%
HALO HALOZYME THERAPEUTICS INC 1.75%
REGN REGENERON PHARMACEUTICALS 1.70%
UTHR UNITED THERAPEUTICS CORP 1.70%
SYRE SPYRE THERAPEUTICS INC 1.69%
NTRA NATERA INC 1.68%
TGTX TG THERAPEUTICS INC 1.62%
ORKA ORUKA THERAPEUTICS INC 1.60%
VRTX VERTEX PHARMACEUTICALS INC 1.59%
NBIX NEUROCRINE BIOSCIENCES INC 1.57%
ALKS ALKERMES PLC 1.50%
BBIO BRIDGEBIO PHARMA INC 1.49%
PTCT PTC THERAPEUTICS INC 1.48%
TWST TWIST BIOSCIENCE CORP 1.46%
INCY INCYTE CORP 1.43%
KYMR KYMERA THERAPEUTICS INC 1.41%
PTGX PROTAGONIST THERAPEUTICS INC 1.41%
CRSP CRISPR THERAPEUTICS AG 1.36%
ROIV ROIVANT SCIENCES LTD 1.34%
BMRN BIOMARIN PHARMACEUTICAL INC 1.33%

Healthcare 99.47%
Financial Services 0.53%

United States 96.79%
Switzerland 1.35%
United Kingdom 1.26%
Netherlands 0.48%
Ireland 0.07%
China 0.04%

Updated 2026-11-08

Funds holding XBI, by value held
Fund	Value held	Weight in fund
MKLOX	$25.24M	0.14%
BDYN	$11.17M	0.37%
EMPB	$5.38M	16.78%
TIH	$3.05M	0.49%
TSCV	$2.09M	1.18%
XNAV	$1.04M	3.82%
GEQ	$908.85K	0.46%
WLTG	$715.44K	0.97%
HFEQ	$296.66K	2.51%
HFND	$216.29K	0.61%
NSCS	$73.67K	0.85%
PSTR	$66.06K	0.10%
SECA	$50.23K	0.01%