Upstream Bio, Inc. UPB

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3.60 USD +0.21 (+6.19%)

Nov 4, 2026, 10:58 AM EST

3.52 Day range 3.81
2.68 52-week range 33.68
YTD
-86.74%
1 year
-85.62%

Analyst view

Consensus: strong buy

Strong buy
Price target (mean) 47.86 +1229.4% upside
Target (low)
35.00
Target (mean)
47.86
Target (high)
75.00
Ratings (0m) 8 8 buy · 0 hold · 0 sell
  • Strong buy2
  • Buy6
  • Hold0
  • Sell0
  • Strong sell0

Recommendation trend

  • This month 8
  • 1 month ago 8
  • 2 months ago 8
  • 3 months ago 8

Earnings and revenue estimates

Consensus for the coming quarters and fiscal years

UPB analyst estimates
PeriodEPS estimateLow – highYear agoEPS growthRevenue estimateRevenue growthAnalysts
Current quarter-0.76667-0.79 – -0.74-0.51-50.3%604.00K+6.7%3
Next quarter-0.71-0.75 – -0.69-0.74+4.0%606.50K-35.3%3
Current year-2.82-2.89 – -2.75-2.66-5.9%1.21M-57.7%3
Next year-3.52-5.33 – -2.07-2.82-24.9%1.22M+0.8%6

Upgrades and downgrades

The latest rating changes

UPB analyst upgrades and downgrades
DateFirmActionFromTo
Mar 27, 2026Evercore ISI GroupDowngradeOutperformIn-Line
Dec 18, 2025MizuhoInitiated—Outperform
Dec 2, 2025LifeSci CapitalInitiated—Outperform
Nov 18, 2025Evercore ISI GroupInitiated—Outperform
Oct 14, 2025Truist SecuritiesInitiated—Buy
Nov 5, 2024JP MorganInitiated—Overweight
Nov 5, 2024William BlairInitiated—Outperform
Nov 5, 2024TD CowenInitiated—Buy
Nov 5, 2024Piper SandlerInitiated—Overweight