Sectors

SEPN
Septerna, Inc.
37.79
2 x 28.35
2 x 49.92
bid
ask
-
1.12
2.87%
03:09 PM
timesize
Ytd35.56%
1y212.35%
37.39
day range
39.10
11.98
52 week range
51.10
Open38.71Prev Close38.91Low37.39High39.10Mkt Cap1.76B
Vol132.03KAvg Vol446.06KEPS-0.53P/EN/AForward P/E-20.05
Beta2.29Short Ratio7.05Inst. Own98.69%DividendN/ADiv YieldN/A
Ex Div DateN/AEarning11-0950-d Avg37.34200-d Avg29.281yr Est54.22

SEPN News

Septerna: GPCR Programs May Be Experimental, But I'm Holding For The Long Term
seekingalpha.com
Septerna: GPCR Programs May Be Experimental, But I'm Holding For The Long Term

Septerna, Inc. has surged >315% since May 2025, driven by its GPCR-focused drug discovery and a high

Septerna Appoints Industry Veteran Rajiv Patni, M.D., as Chief Medical Officer
globenewswire.com
Septerna Appoints Industry Veteran Rajiv Patni, M.D., as Chief Medical Officer

SOUTH SAN FRANCISCO, Calif., Aug. 25, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clin

benzinga.com
JP Morgan Maintains Overweight on Septerna, Raises Price Target to $48

JP Morgan analyst Tessa Romero maintains Septerna (NASDAQ:SEPN) with a Overweight and raises the

benzinga.com
Jones Trading Maintains Buy on Septerna, Raises Price Target to $62

Jones Trading analyst Catherine Novack maintains Septerna (NASDAQ:SEPN) with a Buy and raises the

benzinga.com
Wells Fargo Maintains Overweight on Septerna, Raises Price Target to $50

Wells Fargo analyst Derek Archila maintains Septerna (NASDAQ:SEPN) with a Overweight and raises t

benzinga.com
HC Wainwright & Co. Maintains Buy on Septerna, Raises Price Target to $60

HC Wainwright & Co. analyst Raghuram Selvaraju maintains Septerna (NASDAQ:SEPN) with a Buy an

benzinga.com
Guggenheim Maintains Buy on Septerna, Raises Price Target to $51

Guggenheim analyst Seamus Fernandez maintains Septerna (NASDAQ:SEPN) with a Buy and raises the pr

Septerna, Inc. (SEPN) Reports Q2 Loss, Beats Revenue Estimates
zacks.com
Septerna, Inc. (SEPN) Reports Q2 Loss, Beats Revenue Estimates

Septerna, Inc. (SEPN) came out with a quarterly loss of $0.29 per share versus the Zacks Consensus E

benzinga.com
Septerna Q2 EPS $(0.29) Beats $(0.43) Estimate, Sales $26.746M Beat $17.875M Estimate

Septerna (NASDAQ:SEPN) reported quarterly losses of $(0.29) per share which beat the analyst consens

DigitalOcean, Agios Pharmaceuticals, Kingsoft Cloud And Other Big Stocks Moving Higher On Tuesday
benzinga.com
DigitalOcean, Agios Pharmaceuticals, Kingsoft Cloud And Other Big Stocks Moving Higher On Tuesday

US stocks were mixed, Nasdaq fell 1%. DigitalOcean shares rose after strong revenue growth and earni

Septerna's Chief People Officer Sold Nearly 12,000 Company Shares. What Does That Mean for Investors?
fool.com
Septerna's Chief People Officer Sold Nearly 12,000 Company Shares. What Does That Mean for Investors

Samira Shaikhly sold 11,798 shares of Common Stock on May 26, 2026, for a transaction value of ~$355

benzinga.com
Guggenheim Maintains Buy on Septerna, Lowers Price Target to $45

Guggenheim analyst Seamus Fernandez maintains Septerna (NASDAQ:SEPN) with a Buy and lowers the pr

benzinga.com
HC Wainwright & Co. Reiterates Buy on Septerna, Maintains $40 Price Target

HC Wainwright & Co. analyst Raghuram Selvaraju reiterates Septerna (NASDAQ:SEPN) with a Buy a

benzinga.com
Truist Securities Maintains Buy on Septerna, Raises Price Target to $43

Truist Securities analyst Srikripa Devarakonda maintains Septerna (NASDAQ:SEPN) with a Buy and ra

Is Septerna a Stock to Sell After an Insider Let Go of 15,000 Shares?
fool.com
Is Septerna a Stock to Sell After an Insider Let Go of 15,000 Shares?

15,000 shares were exercised and sold for a total of ~$533,000 on June 22, 2026, at a weighted avera

benzinga.com
Raymond James Maintains Strong Buy on Septerna, Raises Price Target to $53

Raymond James analyst Martin Auster maintains Septerna (NASDAQ:SEPN) with a Strong Buy and raises

benzinga.com
Septerna Announces First Detailed Preclinical Characterization Of SEP-479 Accepted For Oral Presenta

Septerna, Inc. (NASDAQ:SEPN), a clinical-stage biotechnology company pioneering a new era of G prote

Septerna to Present Preclinical Characterization of SEP-479, an Oral PTH1R Agonist for Hypoparathyroidism, at 2026 ENDO Annual Meeting
businesswire.com
Septerna to Present Preclinical Characterization of SEP-479, an Oral PTH1R Agonist for Hypoparathyro

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotec

benzinga.com
HC Wainwright & Co. Reiterates Buy on Septerna, Maintains $40 Price Target

HC Wainwright & Co. analyst Raghuram Selvaraju reiterates Septerna (NASDAQ:SEPN) with a Buy a

Septerna, Inc. (SEPN) Presents at Bank of America Global Healthcare Conference 2026 Transcript
seekingalpha.com
Septerna, Inc. (SEPN) Presents at Bank of America Global Healthcare Conference 2026 Transcript

Septerna, Inc. (SEPN) Presents at Bank of America Global Healthcare Conference 2026 Transcript

Septerna, Inc. (SEPN) Reports Q1 Loss, Tops Revenue Estimates
zacks.com
Septerna, Inc. (SEPN) Reports Q1 Loss, Tops Revenue Estimates

Septerna, Inc. (SEPN) came out with a quarterly loss of $0.19 per share versus the Zacks Consensus E

Septerna Highlights Business Progress and Reports First Quarter 2026 Financial Results
globenewswire.com
Septerna Highlights Business Progress and Reports First Quarter 2026 Financial Results

Compelling Phase 1 Data for SEP-631 (MRGPRX2 NAM) in Healthy Volunteers Support Phase 2b Development

Septerna to Present at Bank of America Securities Health Care Conference
globenewswire.com
Septerna to Present at Bank of America Securities Health Care Conference

SOUTH SAN FRANCISCO, Calif., May 05, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clini

benzinga.com
HC Wainwright & Co. Reiterates Buy on Septerna, Maintains $40 Price Target

HC Wainwright & Co. analyst Raghuram Selvaraju reiterates Septerna (NASDAQ:SEPN) with a Buy a

benzinga.com
Septerna Doses First Participants In Phase 1 Trial Of SEP-479 For Hypoparathyroidism

Trial Designed to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SEP-47

Septerna Announces Initiation of Phase 1 Clinical Trial of SEP-479, an Oral Small Molecule PTH1R Agonist for the Treatment of Hypoparathyroidism
globenewswire.com
Septerna Announces Initiation of Phase 1 Clinical Trial of SEP-479, an Oral Small Molecule PTH1R Ago

Trial Designed to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SEP-47

benzinga.com
JP Morgan Maintains Overweight on Septerna, Raises Price Target to $38

JP Morgan analyst Tessa Romero maintains Septerna (NASDAQ:SEPN) with a Overweight and raises the

benzinga.com
Truist Securities Maintains Buy on Septerna, Raises Price Target to $35

Truist Securities analyst Srikripa Devarakonda maintains Septerna (NASDAQ:SEPN) with a Buy and ra

benzinga.com
Septerna Files Shelf Registration For Future Offerings Of Stock, Debt, Warrants, And Units

Common StockPreferred StockDebt SecuritiesWarrantsUnitsWe may from time to time issue, in one or mor

Septerna, Inc. (SEPN) Reports Q4 Loss, Tops Revenue Estimates
zacks.com
Septerna, Inc. (SEPN) Reports Q4 Loss, Tops Revenue Estimates

Septerna, Inc. (SEPN) came out with a quarterly loss of $0.24 per share versus the Zacks Consensus E

Earnings Breakdown: Septerna Q4
benzinga.com
Earnings Breakdown: Septerna Q4

Earnings Summary: Septerna Q4
benzinga.com
Earnings Summary: Septerna Q4

benzinga.com
Septerna Q4 EPS $(0.24) Misses $0.03 Estimate, Sales $24.118M Miss $32.667M Estimate

Septerna (NASDAQ:SEPN) reported quarterly losses of $(0.24) per share which missed the analyst conse

Septerna Highlights Pipeline Progress and Reports Fourth Quarter and Full Year 2025 Financial Results
globenewswire.com
Septerna Highlights Pipeline Progress and Reports Fourth Quarter and Full Year 2025 Financial Result

Compelling Phase 1 Data for SEP-631 (MRGPRX2 NAM) in Healthy Volunteers Support Phase 2b Development

benzinga.com
Wells Fargo Maintains Overweight on Septerna, Raises Price Target to $48

Wells Fargo analyst Derek Archila maintains Septerna (NASDAQ:SEPN) with a Overweight and raises t

Septerna Stock: A Deep Dive Into Analyst Perspectives (5 Ratings)
benzinga.com
Septerna Stock: A Deep Dive Into Analyst Perspectives (5 Ratings)

benzinga.com
HC Wainwright & Co. Maintains Buy on Septerna, Raises Price Target to $40

HC Wainwright & Co. analyst Raghuram Selvaraju maintains Septerna (NASDAQ:SEPN) with a Buy an

Septerna Announces Positive Phase 1 Data for SEP-631, an Oral MRGPRX2 NAM for the Treatment of Mast Cell-Driven Diseases, and Outlines Initial Phase 2 Development Strategy
globenewswire.com
Septerna Announces Positive Phase 1 Data for SEP-631, an Oral MRGPRX2 NAM for the Treatment of Mast

SEP-631 Demonstrated Robust, Dose-Dependent Inhibition of Icatibant-Induced Skin Wheal Formation, wi

Septerna to Present at TD Cowen 46th Annual Health Care Conference
globenewswire.com
Septerna to Present at TD Cowen 46th Annual Health Care Conference

SOUTH SAN FRANCISCO, Calif., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clin

Septerna (NASDAQ:SEPN) Stock Price Down 5.9% on Insider Selling
defenseworld.net
Septerna (NASDAQ:SEPN) Stock Price Down 5.9% on Insider Selling

Septerna, Inc. (NASDAQ: SEPN - Get Free Report)'s stock price traded down 5.9% during trading on Fri

Septerna Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
globenewswire.com
Septerna Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

SOUTH SAN FRANCISCO, Calif., Feb. 10, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clin

Septerna to Present Data from Phase 1 Clinical Trial of SEP-631 for the Treatment of Mast Cell-Driven Diseases at 2026 AAAAI Annual Meeting
globenewswire.com
Septerna to Present Data from Phase 1 Clinical Trial of SEP-631 for the Treatment of Mast Cell-Drive

SOUTH SAN FRANCISCO, Calif., Feb. 10, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clin

Peakstone Realty Trust, Aquestive Therapeutics, Opera And Other Big Stocks Moving Higher On Monday
benzinga.com
Peakstone Realty Trust, Aquestive Therapeutics, Opera And Other Big Stocks Moving Higher On Monday

The Analyst Verdict: Septerna In The Eyes Of 6 Experts
benzinga.com
The Analyst Verdict: Septerna In The Eyes Of 6 Experts

benzinga.com
HC Wainwright & Co. Maintains Buy on Septerna, Raises Price Target to $35

HC Wainwright & Co. analyst Raghuram Selvaraju maintains Septerna (NASDAQ:SEPN) with a Buy an

Septerna Expands Leadership with Appointment of Industry Veteran Mark A. Wilson as Chief Legal Officer
globenewswire.com
Septerna Expands Leadership with Appointment of Industry Veteran Mark A. Wilson as Chief Legal Offic

SOUTH SAN FRANCISCO, Calif., Jan. 08, 2026 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clin

This Levi Strauss Analyst Begins Coverage On A Bullish Note; Here Are Top 5 Initiations For Tuesday
benzinga.com
This Levi Strauss Analyst Begins Coverage On A Bullish Note; Here Are Top 5 Initiations For Tuesday

benzinga.com
Jones Trading Initiates Coverage On Septerna with Buy Rating, Announces Price Target of $43

Jones Trading analyst Catherine Novack initiates coverage on Septerna (NASDAQ:SEPN) with a Buy ra

benzinga.com
Raymond James Initiates Coverage On Septerna with Strong Buy Rating, Announces Price Target of $38

Raymond James analyst Martin Auster initiates coverage on Septerna (NASDAQ:SEPN) with a Strong Bu

Septerna to Present at 44th Annual J.P. Morgan Healthcare Conference
globenewswire.com
Septerna to Present at 44th Annual J.P. Morgan Healthcare Conference

SOUTH SAN FRANCISCO, Calif., Dec. 17, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clin