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Lyra Therapeutics, Inc. LYRA

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0.19 USD 0.00 (+0.00%)

At closeNov 4, 2026, 4:00 PM EST

0.35 +0.16 +84.47%

After hours · Nov 4, 4:00 PM ET

0.3623 Day range 0.52
0.0004 52-week range 5.65
YTD
-93.83%
1 year
-96.70%

Financial health

Altman Z-Score

-19.16 Distress zone

Bankruptcy-risk model: below 1.81 distress, above 2.99 safe.

Piotroski F-Score

3 / 9 Weak

Nine pass/fail tests of profitability, leverage and efficiency.

FMP rating

C2 / 5 overall

  • DCF 1
  • Return on Equity 5
  • Return on Assets 1
  • Debt / Equity 1
  • P/E 1
  • P/B 1

Valuation

P/E -0.2×
FY 2018: -947×FY 2019: -14.8×FY 2020: -220×FY 2021: -65.1×FY 2022: -85.8×FY 2023: -208×FY 2024: -7.2×FY 2025: -0.2×
FY 2018 5y median -65.1× FY 2025
P/S 120×
FY 2018: 4675×FY 2019: 0.0×FY 2020: 0.0×FY 2021: 9933×FY 2022: 3483×FY 2023: 8366×FY 2024: 438×FY 2025: 120×
FY 2018 5y median 3483× FY 2025
P/B -4.5×
FY 2018: -54.3×FY 2019: 1036×FY 2020: 65.4×FY 2021: 82.5×FY 2022: 58.8×FY 2023: 146×FY 2024: 58.0×FY 2025: -4.5×
FY 2018 5y median 58.8× FY 2025
P/FCF -1.7×
FY 2018: -871×FY 2019: -544×FY 2020: -213×FY 2021: -96.9×FY 2022: -109×FY 2023: -203×FY 2024: -9.3×FY 2025: -1.7×
FY 2018 5y median -96.9× FY 2025
EV/EBITDA -2.1×
FY 2018: -807×FY 2019: -460×FY 2020: -217×FY 2021: -65.4×FY 2022: -87.5×FY 2023: -200×FY 2024: -11.0×FY 2025: -2.1×
FY 2018 5y median -65.4× FY 2025
EV/Sales 156×
FY 2018: 4655×FY 2019: 0.0×FY 2020: 0.0×FY 2021: 9778×FY 2022: 3462×FY 2023: 8368×FY 2024: 434×FY 2025: 156×
FY 2018 5y median 3462× FY 2025
FCF Yield -60.6%
FY 2018: -0.1%FY 2019: -0.2%FY 2020: -0.5%FY 2021: -1.0%FY 2022: -0.9%FY 2023: -0.5%FY 2024: -10.8%FY 2025: -60.6%
FY 2018 5y median -1.0% FY 2025

Profitability

Gross Margin 100.0%
FY 2018: 100.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: -10318.9%FY 2022: 100.0%FY 2023: 100.0%FY 2024: 100.0%FY 2025: 100.0%
FY 2018 5y median 100.0% FY 2025
Operating Margin -7794.5%
FY 2018: -583.5%FY 2019: 0.0%FY 2020: 0.0%FY 2021: -15303.5%FY 2022: -4131.0%FY 2023: -4308.1%FY 2024: -6280.8%FY 2025: -7794.5%
FY 2018 5y median -6280.8% FY 2025
Net Margin -7266.1%
FY 2018: -484.6%FY 2019: 0.0%FY 2020: 0.0%FY 2021: -15267.7%FY 2022: -4055.6%FY 2023: -4023.1%FY 2024: -6090.9%FY 2025: -7266.1%
FY 2018 5y median -6090.9% FY 2025
ROE 269.8%
FY 2018: 5.6%FY 2019: -222.5%FY 2020: -29.7%FY 2021: -126.8%FY 2022: -68.5%FY 2023: -70.1%FY 2024: -805.9%FY 2025: 269.8%
FY 2018 5y median -70.1% FY 2025
ROIC -98.8%
FY 2018: -31.0%FY 2019: -155.0%FY 2020: -28.9%FY 2021: -115.7%FY 2022: -56.9%FY 2023: -52.3%FY 2024: -166.6%FY 2025: -98.8%
FY 2018 5y median -98.8% FY 2025
ROA -80.1%
FY 2018: -23.8%FY 2019: -109.0%FY 2020: -27.4%FY 2021: -79.3%FY 2022: -50.3%FY 2023: -44.0%FY 2024: -140.8%FY 2025: -80.1%
FY 2018 5y median -79.3% FY 2025

Growth (YoY)

Revenue -74.1%
FY 2018: 0.0%FY 2019: -100.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 378.2%FY 2023: 14.3%FY 2024: -1.5%FY 2025: -74.1%
FY 2018 FY 2025
Operating Income 67.8%
FY 2018: 0.0%FY 2019: -127.6%FY 2020: -34.4%FY 2021: -96.4%FY 2022: -29.1%FY 2023: -19.2%FY 2024: -43.5%FY 2025: 67.8%
FY 2018 FY 2025
EPS (diluted) -1202.1%
FY 2018: 0.0%FY 2019: -6277.6%FY 2020: 95.9%FY 2021: -29.3%FY 2022: 45.4%FY 2023: 31.1%FY 2024: -13.5%FY 2025: -1202.1%
FY 2018 FY 2025
Free Cash Flow 60.0%
FY 2018: 0.0%FY 2019: -109.2%FY 2020: -64.1%FY 2021: -27.4%FY 2022: -49.1%FY 2023: -47.8%FY 2024: -12.4%FY 2025: 60.0%
FY 2018 FY 2025

Financial Health

Current Ratio 1.7×
FY 2018: 12.7×FY 2019: 1.9×FY 2020: 15.5×FY 2021: 2.6×FY 2022: 7.0×FY 2023: 5.3×FY 2024: 3.4×FY 2025: 1.7×
FY 2018 5y median 3.4× FY 2025
Quick Ratio 1.7×
FY 2018: 12.7×FY 2019: 1.9×FY 2020: 15.5×FY 2021: 2.6×FY 2022: 7.0×FY 2023: 5.3×FY 2024: 3.4×FY 2025: 1.7×
FY 2018 5y median 3.4× FY 2025
Debt / Equity -2.8×
FY 2018: 0.0×FY 2019: 0.5×FY 2020: 0.0×FY 2021: 0.0×FY 2022: 0.1×FY 2023: 0.3×FY 2024: 3.0×FY 2025: -2.8×
FY 2018 5y median 0.1× FY 2025
Net Debt / EBITDA -0.5×
FY 2018: 3.3×FY 2019: 0.4×FY 2020: 3.3×FY 2021: 1.0×FY 2022: 0.5×FY 2023: -0.1×FY 2024: 0.1×FY 2025: -0.5×
FY 2018 5y median 0.1× FY 2025
Interest Coverage 0.0×
FY 2018: 0.0×FY 2019: 0.0×FY 2020: 0.0×FY 2021: 0.0×FY 2022: 0.0×FY 2023: 0.0×FY 2024: 0.0×FY 2025: 0.0×
FY 2018 5y median 0.0× FY 2025

Dividends

Dividend Yield 0.0%
FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2018 5y median 0.0% FY 2025
Payout Ratio 0.0%
FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2018 5y median 0.0% FY 2025

Annual · latest fiscal year ends 2025-12-31