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Lexicon Pharmaceuticals, Inc. LXRX

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1.82 USD +0.20 (+12.73%)

Nov 6, 2026, 2:26 PM EST

1.61 Day range 1.84
1.10 52-week range 2.68
YTD
+57.83%
1 year
+26.92%

Financial health

Altman Z-Score

-6.23 Distress zone

Bankruptcy-risk model: below 1.81 distress, above 2.99 safe.

Piotroski F-Score

3 / 9 Weak

Nine pass/fail tests of profitability, leverage and efficiency.

Rating

D+1 / 5 overall

  • DCF 1
  • Return on Equity 1
  • Return on Assets 1
  • Debt / Equity 1
  • P/E 1
  • P/B 2

Valuation

P/E -8.2×
FY 2016: -10.2×FY 2017: -8.0×FY 2018: -5.8×FY 2019: 3.4×FY 2020: -5.4×FY 2021: -6.5×FY 2022: -3.1×FY 2023: -1.9×FY 2024: -1.2×FY 2025: -8.2×
FY 2016 5y median -3.1× FY 2025
P/S 8.4×
FY 2016: 17.2×FY 2017: 11.5×FY 2018: 11.1×FY 2019: 1.4×FY 2020: 15.8×FY 2021: 1926×FY 2022: 2277×FY 2023: 281×FY 2024: 7.6×FY 2025: 8.4×
FY 2016 5y median 281× FY 2025
P/B 3.9×
FY 2016: 9.1×FY 2017: 19.9×FY 2018: -0.5×FY 2019: 3.8×FY 2020: 2.4×FY 2021: 5.1×FY 2022: 2.7×FY 2023: 3.6×FY 2024: 1.6×FY 2025: 3.9×
FY 2016 5y median 3.6× FY 2025
P/FCF -6.2×
FY 2016: -8.2×FY 2017: -5.6×FY 2018: -4.7×FY 2019: 3.9×FY 2020: -2.6×FY 2021: -6.5×FY 2022: -3.5×FY 2023: -2.1×FY 2024: -1.3×FY 2025: -6.2×
FY 2016 5y median -3.5× FY 2025
EV/EBITDA -10.8×
FY 2016: -9.5×FY 2017: -7.8×FY 2018: -8.2×FY 2019: 4.4×FY 2020: -6.5×FY 2021: -5.9×FY 2022: -3.3×FY 2023: -2.5×FY 2024: -1.5×FY 2025: -10.8×
FY 2016 5y median -3.3× FY 2025
EV/Sales 8.9×
FY 2016: 14.3×FY 2017: 10.8×FY 2018: 12.5×FY 2019: 2.0×FY 2020: 11.1×FY 2021: 1718×FY 2022: 2342×FY 2023: 350×FY 2024: 8.9×FY 2025: 8.9×
FY 2016 5y median 350× FY 2025
FCF Yield -16.3%
FY 2016: -12.2%FY 2017: -17.9%FY 2018: -21.2%FY 2019: 25.8%FY 2020: -37.7%FY 2021: -15.4%FY 2022: -28.5%FY 2023: -48.0%FY 2024: -76.1%FY 2025: -16.3%
FY 2016 5y median -28.5% FY 2025

Profitability

Gross Margin 99.4%
FY 2016: -96.8%FY 2017: 97.9%FY 2018: 96.1%FY 2019: 99.0%FY 2020: 92.0%FY 2021: -18371.8%FY 2022: -37681.3%FY 2023: -4798.0%FY 2024: 98.0%FY 2025: 99.4%
FY 2016 5y median -4798.0% FY 2025
Operating Margin -98.2%
FY 2016: -164.6%FY 2017: -151.3%FY 2018: -163.4%FY 2019: 43.9%FY 2020: -199.2%FY 2021: -29224.8%FY 2022: -72489.2%FY 2023: -14265.0%FY 2024: -634.2%FY 2025: -98.2%
FY 2016 5y median -14265.0% FY 2025
Net Margin -101.1%
FY 2016: -169.7%FY 2017: -142.9%FY 2018: -190.7%FY 2019: 40.4%FY 2020: -244.1%FY 2021: -29449.0%FY 2022: -73341.0%FY 2023: -14710.9%FY 2024: -644.8%FY 2025: -101.1%
FY 2016 5y median -14710.9% FY 2025
ROE -46.8%
FY 2016: -89.9%FY 2017: -247.7%FY 2018: 8.2%FY 2019: 111.1%FY 2020: -37.5%FY 2021: -77.3%FY 2022: -87.0%FY 2023: -190.2%FY 2024: -137.3%FY 2025: -46.8%
FY 2016 5y median -87.0% FY 2025
ROIC -28.7%
FY 2016: -46.5%FY 2017: -39.6%FY 2018: -44.3%FY 2019: 38.9%FY 2020: -28.3%FY 2021: -75.2%FY 2022: -58.4%FY 2023: -86.2%FY 2024: -77.5%FY 2025: -28.7%
FY 2016 5y median -75.2% FY 2025
ROA -27.2%
FY 2016: -29.7%FY 2017: -29.6%FY 2018: -42.4%FY 2019: 31.2%FY 2020: -28.7%FY 2021: -64.1%FY 2022: -52.5%FY 2023: -77.2%FY 2024: -67.2%FY 2025: -27.2%
FY 2016 5y median -64.1% FY 2025

Growth (YoY)

Revenue 60.2%
FY 2016: -35.9%FY 2017: 8.4%FY 2018: -30.0%FY 2019: 409.5%FY 2020: -92.5%FY 2021: -98.8%FY 2022: -53.4%FY 2023: 766.2%FY 2024: 2481.5%FY 2025: 60.2%
FY 2016 FY 2025
Operating Income 75.2%
FY 2016: -9443.0%FY 2017: 0.3%FY 2018: 24.4%FY 2019: 237.0%FY 2020: -133.8%FY 2021: -82.2%FY 2022: -15.7%FY 2023: -70.5%FY 2024: -14.8%FY 2025: 75.2%
FY 2016 FY 2025
EPS (diluted) 77.8%
FY 2016: -2908.8%FY 2017: 9.6%FY 2018: 7.3%FY 2019: 197.4%FY 2020: -156.8%FY 2021: 3.2%FY 2022: -1.6%FY 2023: -29.0%FY 2024: 21.3%FY 2025: 77.8%
FY 2016 FY 2025
Free Cash Flow 62.3%
FY 2016: -195.6%FY 2017: -5.6%FY 2018: 19.9%FY 2019: 176.5%FY 2020: -225.8%FY 2021: 38.3%FY 2022: -2.2%FY 2023: -80.1%FY 2024: -10.7%FY 2025: 62.3%
FY 2016 FY 2025

Financial Health

Current Ratio 4.9×
FY 2016: 2.2×FY 2017: 2.6×FY 2018: 4.7×FY 2019: 5.2×FY 2020: 3.4×FY 2021: 4.0×FY 2022: 6.1×FY 2023: 5.6×FY 2024: 5.4×FY 2025: 4.9×
FY 2016 5y median 5.4× FY 2025
Quick Ratio 4.9×
FY 2016: 2.2×FY 2017: 2.6×FY 2018: 4.6×FY 2019: 5.1×FY 2020: 3.4×FY 2021: 4.0×FY 2022: 6.1×FY 2023: 5.6×FY 2024: 5.4×FY 2025: 4.9×
FY 2016 5y median 5.4× FY 2025
Debt / Equity 0.6×
FY 2016: 0.6×FY 2017: 4.7×FY 2018: -0.2×FY 2019: 2.1×FY 2020: 0.1×FY 2021: 0.0×FY 2022: 0.5×FY 2023: 1.1×FY 2024: 0.7×FY 2025: 0.6×
FY 2016 5y median 0.6× FY 2025
Net Debt / EBITDA -0.7×
FY 2016: 1.9×FY 2017: 0.5×FY 2018: -0.9×FY 2019: 1.4×FY 2020: 2.8×FY 2021: 0.7×FY 2022: -0.1×FY 2023: -0.5×FY 2024: -0.2×FY 2025: -0.7×
FY 2016 5y median -0.2× FY 2025
Interest Coverage -5.9×
FY 2016: -20.9×FY 2017: -19.6×FY 2018: -5.0×FY 2019: 6.8×FY 2020: -3.3×FY 2021: -109×FY 2022: -36.2×FY 2023: -13.1×FY 2024: -12.7×FY 2025: -5.9×
FY 2016 5y median -13.1× FY 2025

Dividends

Dividend Yield 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025
Payout Ratio 0.0%
FY 2016: 0.0%FY 2017: 0.0%FY 2018: 0.0%FY 2019: 0.0%FY 2020: 0.0%FY 2021: 0.0%FY 2022: 0.0%FY 2023: 0.0%FY 2024: 0.0%FY 2025: 0.0%
FY 2016 5y median 0.0% FY 2025

Annual · latest fiscal year ends 2025-12-31