Castle Biosciences, Inc. CSTL

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35.14 USD +0.20 (+0.57%)

At closeNov 3, 2026, 4:00 PM EST

35.14 0.00 0.00%

After hours · Nov 3, 4:00 PM ET

34.83 Day range 36.00
17.72 52-week range 44.28
YTD
-9.67%
1 year
+35.21%
Market cap
1.07B
Revenue (ttm)
357.28M
Profit margin
-5.43%
EPS (ttm)
-0.64
Shares out
30.55M
Forward P/E
-37.58
YTD return
-9.67%
1-year return
+35.21%
Volume
455.61K
Avg volume
372.19K
Open
35.32
Previous close
34.94
Day's range
34.83 – 36.00
52-week range
17.72 – 44.28
Beta
0.95
Analysts
Strong Buy
Price target
46.70 (+32.9%)
Earnings date
Nov 5, 2026

1m -0.18 (-0.51%)

3535.5036Nov 335.14

Key statistics

Enterprise value
837.24M
PEG ratio
0.00
Price / sales
3.00
Price / book
2.28
Dividend yield
0.00%
Payout ratio
0.00%
Revenue growth
20.10%
Free cash flow
-7.26M
Total cash
266.80M
Total debt
36.65M
Return on equity
-4.20%
Short % of float
6.76%
50-day average
34.23
200-day average
28.50

Financials — quick view

All financials
CSTL Revenue — quarterly 103.55M
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
CSTL Net income — quarterly -2.06M
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026
CSTL EPS — quarterly -0.07
2022-Q3 20222022-Q4 20222023-Q1 20232023-Q2 20232023-Q3 20232023-Q4 20232024-Q1 20242024-Q2 20242024-Q3 20242024-Q4 20242025-Q1 20252025-Q2 20252025-Q3 20252025-Q4 20252026-Q1 20262026-Q2 2026

Earnings

CSTL recent earnings
Report dateQuarter endingEPS estimateEPS reportedSurpriseSurprise %
Nov 5, 2026Sep 30, 2026-0.348———
Jul 30, 2026Jun 30, 2026-0.40697-0.07+0.34+82.80%
May 6, 2026Mar 31, 2026-0.49-0.490.000.00%
Feb 26, 2026Dec 31, 2025-0.23-0.08+0.15+65.22%
Nov 3, 2025Sep 30, 2025-0.34-0.02+0.32+94.12%
Aug 4, 2025Jun 30, 2025-0.510.15+0.66+129.41%

Upgrades / downgrades

CSTL analyst upgrades and downgrades
DateFirmActionFromTo
Aug 3, 2026BTIGmainBuyBuy
Jun 25, 2026Roth Capitalinit—Buy
May 13, 2026BTIGmainBuyBuy
May 7, 2026BairdmainOutperformOutperform
Apr 20, 2026Canaccord GenuitymainBuyBuy
Feb 27, 2026BairdmainOutperformOutperform

About Castle Biosciences, Inc.

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE; AdvanceAD-Tx, a non-invasive GEP test which is designed to guide systemic treatment selection for patients aged 12 years and older with moderateto-severe AD; DecisionDx-SCC, a GEP test for cutaneous squamous cell carcinoma; and MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions. It also provides DecisionDx-UM, a risk stratification GEP test that predicts the risk of metastasis for patients with uveal melanoma. The company offers its products to dermatology and gastroenterology markets. The company was incorporated in 2007 and is headquartered in Friendswood, Texas.

Sector
Healthcare
Industry
Diagnostics & Research
Country
United States

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Insider holders

CSTL insider holders
InsiderRelationLatest transactionDateShares held
BRADBURY DANIEL MDirectorConversion of Exercise of derivative securityMay 21, 202635,631
CAPLE KIMDirectorConversion of Exercise of derivative securityMay 21, 202636,121
COTTON RODNEYDirectorConversion of Exercise of derivative securityMay 21, 202632,998
GOLDBERG ELLENDirectorConversion of Exercise of derivative securityMay 21, 202640,921
HARRISON MILES DDirectorConversion of Exercise of derivative securityMay 21, 202635,631
JUVENAL TOBIN WOfficerSaleOct 25, 202645,431

Institution ownership

CSTL institution ownership
Holder% heldSharesValueReported
Blackrock Inc.10.78%3,291,963115.68MJun 29, 2026
RTW Investments LP9.09%2,778,33597.63MJun 29, 2026
Principal Financial Group, Inc.4.91%1,500,89752.74MSep 29, 2026
Vanguard Capital Management LLC4.01%1,226,49743.10MJun 29, 2026
Acadian Asset Management. LLC3.01%918,66832.28MJun 29, 2026
Allianz Asset Management GmbH2.88%879,25830.90MJun 29, 2026

Fund ownership

CSTL fund ownership
Holder% heldSharesValueReported
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund2.79%852,70429.96MJun 29, 2026
Fidelity Rutland Square TRT II-Strategic Advisers U.S. Total Stock Fd.2.60%793,43827.88MAug 30, 2026
iShares Trust-iShares Russell 2000 ETF2.54%776,29827.28MSep 29, 2026
Principal Funds, Inc-SmallCap Fund2.37%725,13825.48MJul 30, 2026
VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund1.12%342,65512.04MJun 29, 2026
Fidelity Salem Street Trust-Fidelity Small Cap Index Fund1.07%327,80611.52MAug 30, 2026