Castle Biosciences, Inc. CSTL
At closeNov 6, 2026, 4:00 PM EST
After hours · Nov 6, 4:00 PM ET
- YTD
- -16.40%
- 1 year
- -3.07%
- Market cap
- 993.47M
- Revenue (ttm)
- 357.28M
- Profit margin
- -5.43%
- EPS (ttm)
- -0.64
- Shares out
- 30.55M
- Forward P/E
- -38.24
- YTD return
- -16.40%
- 1-year return
- -3.07%
- Volume
- 981.63K
- Avg volume
- 365.80K
- Open
- 34.56
- Previous close
- 34.20
- Day's range
- 31.81 – 35.69
- 52-week range
- 17.72 – 44.28
- Beta
- 0.95
- Analysts
- Strong Buy
- Price target
- 46.70 (+43.6%)
- Earnings date
- Nov 5, 2026
5D -4.61 (-12.42%)
Key statistics
- Enterprise value
- 843.35M
- PEG ratio
- 0.00
- Price / sales
- 3.06
- Price / book
- 2.32
- Dividend yield
- 0.00%
- Payout ratio
- 0.00%
- Revenue growth
- 20.10%
- Free cash flow
- -7.26M
- Total cash
- 266.80M
- Total debt
- 36.65M
- Return on equity
- -4.20%
- Short % of float
- 6.76%
- 50-day average
- 34.27
- 200-day average
- 28.47
Analyst view
Consensus: strong buy
- Target (low)
- 35.00
- Target (mean)
- 46.70
- Target (high)
- 60.00
- Strong buy0
- Buy10
- Hold0
- Sell0
- Strong sell0
Next earnings
Nov 5, 2026
Expected Nov 5, 2026. Consensus EPS estimate -0.346.
Financials — quick view
Earnings
| Report date | Quarter ending | EPS estimate | EPS reported | Surprise | Surprise % |
|---|---|---|---|---|---|
| Nov 5, 2026 | Sep 30, 2026 | -0.348 | — | — | — |
| Jul 30, 2026 | Jun 30, 2026 | -0.40697 | -0.07 | +0.34 | +82.80% |
| May 6, 2026 | Mar 31, 2026 | -0.49 | -0.49 | 0.00 | 0.00% |
| Feb 26, 2026 | Dec 31, 2025 | -0.23 | -0.08 | +0.15 | +65.22% |
| Nov 3, 2025 | Sep 30, 2025 | -0.34 | -0.02 | +0.32 | +94.12% |
| Aug 4, 2025 | Jun 30, 2025 | -0.51 | 0.15 | +0.66 | +129.41% |
Upgrades / downgrades
| Date | Firm | Action | From | To |
|---|---|---|---|---|
| Aug 3, 2026 | BTIG | main | Buy | Buy |
| Jun 25, 2026 | Roth Capital | init | — | Buy |
| May 13, 2026 | BTIG | main | Buy | Buy |
| May 7, 2026 | Baird | main | Outperform | Outperform |
| Apr 20, 2026 | Canaccord Genuity | main | Buy | Buy |
| Feb 27, 2026 | Baird | main | Outperform | Outperform |
About Castle Biosciences, Inc.
Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE; AdvanceAD-Tx, a non-invasive GEP test which is designed to guide systemic treatment selection for patients aged 12 years and older with moderateto-severe AD; DecisionDx-SCC, a GEP test for cutaneous squamous cell carcinoma; and MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions. It also provides DecisionDx-UM, a risk stratification GEP test that predicts the risk of metastasis for patients with uveal melanoma. The company offers its products to dermatology and gastroenterology markets. The company was incorporated in 2007 and is headquartered in Friendswood, Texas.
- Sector
- Healthcare
- Industry
- Diagnostics & Research
- Country
- United States
- Website
- castlebiosciences.com
News
Keybanc Maintains Overweight on Castle Biosciences, Raises Price Target to $40
What Castle Biosciences (CSTL) Said on Its Q3 Earnings Call
Castle Biosciences, Inc. (CSTL) Q3 2026 Earnings Call Transcript
Castle Biosciences Q3 2026 Earnings Call Transcript Castle Biosciences Raises FY2026 Sales Guidance from $365.000M-$375.000M to $385.000M-$395.000M vs $373.753M Est
Castle Biosciences To Present New Data From Three Studies Evaluating Its TissueCypher Barrett's Esophagus Test At ACG 2026 Annual Scientific Meeting And Postgraduate Course
Castle Biosciences To Present New Data On DecisionDx-Melanoma At EADV Congress 2026
Castle Biosciences Announces Publication Of New Study Highlighting Demand For Molecular Testing In Atopic Dermatitis
Castle Biosciences Announces Opening Of New Laboratory And Office Facility In Scottsdale, Arizona
BTIG Maintains Buy on Castle Biosciences, Raises Price Target to $44
Your note
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Insider holders
| Insider | Relation | Latest transaction | Date | Shares held |
|---|---|---|---|---|
| BRADBURY DANIEL M | Director | Conversion of Exercise of derivative security | May 21, 2026 | 35,631 |
| CAPLE KIM | Director | Conversion of Exercise of derivative security | May 21, 2026 | 36,121 |
| COTTON RODNEY | Director | Conversion of Exercise of derivative security | May 21, 2026 | 32,998 |
| GOLDBERG ELLEN | Director | Conversion of Exercise of derivative security | May 21, 2026 | 40,921 |
| HARRISON MILES D | Director | Conversion of Exercise of derivative security | May 21, 2026 | 35,631 |
| JUVENAL TOBIN W | Officer | Sale | Oct 25, 2026 | 45,431 |
Institution ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| Blackrock Inc. | 10.78% | 3,291,963 | 117.69M | Jun 29, 2026 |
| RTW Investments LP | 9.09% | 2,778,335 | 99.33M | Jun 29, 2026 |
| Principal Financial Group, Inc. | 4.91% | 1,500,897 | 53.66M | Sep 29, 2026 |
| Vanguard Capital Management LLC | 4.01% | 1,226,497 | 43.85M | Jun 29, 2026 |
| Acadian Asset Management. LLC | 3.01% | 918,668 | 32.84M | Jun 29, 2026 |
| Allianz Asset Management GmbH | 2.88% | 879,258 | 31.43M | Jun 29, 2026 |
Fund ownership
| Holder | % held | Shares | Value | Reported |
|---|---|---|---|---|
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | 2.79% | 852,704 | 30.48M | Jun 29, 2026 |
| Fidelity Rutland Square TRT II-Strategic Advisers U.S. Total Stock Fd. | 2.60% | 793,438 | 28.37M | Aug 30, 2026 |
| iShares Trust-iShares Russell 2000 ETF | 2.54% | 776,298 | 27.75M | Sep 29, 2026 |
| Principal Funds, Inc-SmallCap Fund | 2.37% | 725,138 | 25.92M | Jul 30, 2026 |
| VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund | 1.12% | 342,655 | 12.25M | Jun 29, 2026 |
| Fidelity Salem Street Trust-Fidelity Small Cap Index Fund | 1.07% | 327,806 | 11.72M | Aug 30, 2026 |
