Reported Sunday, Johnson & Johnson Says Pasritamig And JNJ-9401 Achieve 73% PSA Response With No Grade 3 Or Higher Treatment-Related Adverse Events In Phase 1 Prostate Cancer Study, Supporting Outpatient Dosing
Benzinga Newsdesk 1 day ago
News
First-of-its-kind dual-antigen-targeted bispecific regimen of pasritamig and JNJ-9401 directed at two prostate cancer proteins, KLK2 and PSMA, using complementary signals to activate T cells against cancer Deep and
- First-of-its-kind dual-antigen-targeted bispecific regimen of pasritamig and JNJ-9401 directed at two prostate cancer proteins, KLK2 and PSMA, using complementary signals to activate T cells against cancer
- Deep and sustained PSA responses observed with every-six-week dosing, with 73% (11 of 15 patients) achieving reductions of at least 50% and nearly half achieving reductions of at least 90% in Phase 1 study
- With an encouraging safety profile, findings show potential for outpatient dosing as the combination advances to Phase 3