BOTTOM PLAYS PAY!
Man Davies
Posts (4982)
BOTTOM PLAYS PAY!
BOTTOM PLAYS PAY!
OH SHIT
Cassavas PTI125 study shows that PTI125 has a significant affect on the reduction of neuro inflammation. Neuro inflammation is the primary precursor to the onset of Alzheimer’s. IMO, PTI125 is a blockbuster drug, just due to its effect on neuro inflammation and the prevention of Alzheimers.
PTI-125 significantly reduced a secondary endpoint, CSF levels of IL1-beta (p<0.035), a core biomarker of neuroinflammation, from baseline to Day 28. Drug was safe and well-tolerated.
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In Alzheimer's disease (AD) neuroinflammation, instead of being a mere bystander activated by emerging senile plaques and neurofibrillar tangles, contributes as much or more to the pathogenesis as do the plaques and tangles themselves 1. This is underlined by recent findings that genes for immune receptors, including TREM2 2 and CD33 3,4, are associated with AD. Analysis of clinical manifestations that precede AD, such as mild cognitive impairment (MCI), further argue for an early and substantial involvement of inflammation in the pathogenesis of the disease.
BOOM SHAKA LAKA
BOOM SHAKA LAKA