Piloto

Getting ready to take off . This will be monumental

Next Generation of Covid-19 Vaccines Could Be Pill or Spray

Drugmakers and government labs are developing doses easier to take and transport to tackle coronavirus variants and avert future pandemics

By and May 3, 2021 5:33 am ET
The next generation of Covid-19 vaccines in development could come as a pill or a nasal spray and be easier to store and transport than the current handful of shots that form the backbone of the world-wide vaccination effort.

These newer vaccines, from U.S. government labs and companies including Sanofi SA, Altimmune Inc. and Gritstone Oncology Inc., also have the potential to provide longer-lasting immune responses and be more potent against newer and multiple viral variants, possibly helping to head off future pandemics, the companies say.

Vaccines currently authorized for use in the U.S. from Pfizer Inc. and its partner BioNTech SE, as well as Moderna Inc., must be transported and stored at low temperatures and require two doses administered weeks apart.

New vaccines could “constitute some improvement” over those limitations and more easily accommodate vaccination efforts in rural areas, said Gregory Poland, professor and vaccine researcher at the Mayo Clinic in Rochester, Minn. “You will see second-generation, third-generation vaccines,” he said.

There are 277 Covid-19 vaccines in development globally, of which 93 have entered human testing, according to the World Health Organization. Most of the vaccines in clinical testing are injected, but there are two oral formulations and seven nasal-spray formulations

I really do not know what is the big discussion in here when all Reddit is in the house . This will flight not matter what !

Phl holding . Live next to the ocgn building

It is just Friday . Go sleep . Pray for all those affected by this freaking virus and do not let it drop on Monday . I will be ready to buy at $9.15 . I have followed this stock for more than a year and every time they come with presentations but nothing approved . They are still in phase 2. Thought I think the technology is promising and that is why I still keep a good size of shares, it will be nothing extraordinary in that presentation . I am most waiting for a buy out. Which I think it may occur any time because of the potential .

Govt explores possibility of producing Covaxin abroad

The move, which is expected to increase availability of and access to vaccines, especially in the global South comes at a time when India is looking to boost domestic production of the vaccines.

The move, which is expected to increase availability of and access to vaccines, especially in the global South comes at a time when India is looking to boost domestic production of the vaccines.
Centre is exploring the possibility of offering the locally developed coronavirus vaccine, Covaxin that has been jointly developed by Bharat Biotech and the Indian Council of Medical Research (ICMR), for production abroad through a technology transfer between commercial entities amid supply crunch, according to government officials aware of the development.

“There is a need to meet the demand for Covid-19 vaccines in view of the new mutation of the virus to more infectious nature. We have decided to offer Covaxin to any interested foreign countries. The production would be done through technology transfer between commercial entities. Terms and conditions for the same would have to be finalised by the licence holder, Bharat Biotech,” one of the officials said on condition of anonymity.

This will also be done with any future Indian vaccines, this person added. “It has also been communicated to missions abroad to seek interested countries for production abroad.”

The move, which is expected to increase availability of and access to vaccines, especially in the global South comes at a time when India is looking to boost domestic production of the vaccines. The government last week decided to offer an advance (or supplier’s credit) of over ₹4,500 crore to Serum Institute of India and Bharat Biotech. Bharat Biotech on April 20 announced it will scale up of manufacturing capacity to produce 700 million doses of Covaxin annually.

India’s indigenous vaccine, Covaxin is developed by Bharat Biotech in collaboration with the Indian Council of Medical Research (ICMR) - National Institute of Virology (NIV). The indigenous, inactivated vaccine is developed and manufactured in Bharat Biotech’s BSL-3 (Bio-Safety Level 3) high containment facility.

It is, however, not clear whether ICMR shares Intellectual Property rights with Bharat Biotech on Covaxin. Nor was it immediately clear how and why the government is involved in what should seesntially be a technology transfer arrangement between two companies.

Bharat Biotech, ICMR and the ministry of health did not respond to queries seeking comment.

Covaxin recently came in for praise from the US’ top pandemic expert Dr Anthony Fauci, who said it “neutralises” 617 variants, according to PTI.

In a statement issued on April 20, Bharat Biotech said it was exploring manufacturing partnerships with partners in other countries, who have prior expertise with commercial scale manufacture of inactivated viral vaccines under biosafety containment.

“Manufacturing scale up has been carried out in a stepwise manner across multiple facilities at Hyderabad, and Bangalore. Inactivated vaccines, while highly safe, are extremely complex and expensive to manufacture, resulting in lower yields when compared to live virus vaccines,” it added in the statement.

The company also said Covaxin has received Emergency Use Authorisation in several countries across the globe with another 60 in process. It has been granted EUAs in Mexico, Philippines, Iran, Paraguay, Guatemala, Nicaragua, Guyana, Venezuela, Botswana, Zimbabwe, among several other countries. It is in the process of getting EUAs in the US and Europe, according to Bharat Biotech.

“I think, in principle this is great. Expanding manufacturing capacity outside is important not only to increase doses but increase capacity in other parts of the world, “ said Gagandeep Kang, professor at Christian Medical College and board member of Coalition for Epidemic Preparedness Innovations (CEPI).

Any news? Uuhhm! I will be checking every second . It looks like a trap

It got loose. keep buying the ask . Hedge beaten up

Lets go a save the world . Pass 13.33 and then next stop at 20.14 . Big up up there

13.33 the resistance point to beat up. Lets go !