Azitra To Present Pipeline Updates Including Results For ATR-COSF Program, Designed To Deliver Filaggrin Domains Into Human Skin To Reduce Appearance Of Fine Lines And Wrinkles, At BIO-Europe

Initial results from first-in-human study with ATR-COSF anticipated by year-end

BRANFORD, Conn., Nov. 10, 2026 /PRNewswire/ -- Azitra, Inc. ("Azitra" or the "Company") (NYSE:AZTR), a clinical-stage biopharmaceutical company focused on developing innovative therapies for precision dermatology, today announced that Cofounder and Chief Operating Officer, Travis Whitfill, Ph.D., MPH, will present pipeline updates including results for its ATR-COSF program, which is designed to deliver filaggrin domains into human skin to reduce the appearance of fine lines and wrinkles, at the BIO-Europe® conference in Cologne, Germany on November 10, 2026, at 4:45 pm CET.

In the presentation, Dr. Whitfill will highlight data from an ex vivo human torso skin model, in which ATR-COSF, a recombinant filaggrin protein designed for topical use, elicited a 56% reduction in wrinkles from baseline. In addition, ATR-COSF was shown to improve elasticity and improve the depth of wrinkles compared to vehicle in ex vivo models at 48 hours.

Dr. Whitfill's presentation will also provide updates on ATR-04 being studied for rashes associated with commonly prescribed cancer medications. The Phase 1/2 trial of ATR-04 is ongoing and was expanded in October 2026 to include patients with rashes due to KRAS and MEK inhibitors, in addition to EGFR inhibitors, as well as patients with neurofibromatosis type 1 (NF1) with rash associated with MEK inhibitors. Combined, approximately 85,000 patients undergo KRAS or MEK inhibitor treatment in the United States annually. The addition of these patients further broadens the potential clinical applications being explored for ATR-04 on top of the approximately 220,000 patients undergoing EGFR inhibitor treatment in the United States annually.

In addition to presenting the progress of Azitra's pipeline, Dr. Whitfill will also conduct one-on-one meetings with potential partners and investors during the conference. The presentation slides will be available online at ir.azitrainc.com.