IGC Pharma Reaches Key Enrollment Milestone Of 65% For Ongoing Phase 2 CALMA Clinical Trial Evaluating IGC-AD1 For Treatment Of Agitation In Alzheimer's Disease

IGC Pharma, Inc. (NYSE:IGC) ("IGC" or the "Company"), a clinical-stage biotechnology company leveraging Artificial Intelligence (AI) to develop innovative treatments for Alzheimer's disease, today announced it has reached a key enrollment milestone of 65% for its ongoing Phase 2 CALMA clinical trial evaluating IGC-AD1 for the treatment of agitation in Alzheimer's disease.

This milestone marks a significant step in advancing IGC-AD1, the Company's proprietary formulation, and demonstrates continued strong momentum toward full enrollment consistent with the goal of completing the trial in early 2026.

Enrollment has accelerated, meaningfully, supported by the Company's data-driven digital recruitment strategy. Approximately 25% of all participants enrolled to date were recruited through IGC Pharma's targeted social-media campaigns, while 75% were enrolled directly through clinical-site efforts.

Agitation is a disruptive and highly prevalent symptom affecting over 76% of individuals living with Alzheimer's disease. Interim analyses of the Phase 2 trial, previously announced by the Company, have shown clinical and statistically significant reductions in agitation, underscoring the therapeutic potential of IGC-AD1. The Company continues to expand its clinical operations and strengthen site performance across the United States and Canada.