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Foghorn Therapeutics Presents New Data On Selective SMARCA2 Inhibitor FHD-909 And Selective CBP And Selective EP300 Degrader Programs

Benzinga Newsdesk 1 year ago

BiotechNewsEventsGeneral

FHD-909 (LY4050784) advancing in Phase 1 trial in SMARCA4 (BRG1) mutated cancers, with non-small cell lung cancer (NSCLC) as the primary target population- Preclinical synergistic anti-tumor activity of FHD-909 in

FHD-909 (LY4050784) advancing in Phase 1 trial in SMARCA4 (BRG1) mutated cancers, with non-small cell lung cancer (NSCLC) as the primary target population

- Preclinical synergistic anti-tumor activity of FHD-909 in combination with pembrolizumab and KRAS inhibitors supports clinical exploration

- Selective CBP degrader combination approaches show promise in preclinical ER+ breast cancer models

- Further preclinical characterization of the therapeutic potential of the Selective EP300 degrader program to treat advanced hematological malignancies

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