Curis, Inc., a biotechnology company, engages in the discovery and development of drug candidates for the treatment of human cancers in the United States. Its clinical stage drug candidates include Emavusertib, an oral small molecule IRAK4 kinase inhibitor, which is in a Phase 1/2 open-label, single arm expansion trial in patients with relapsed or refractory, or R/R, AML and high-risk myelodysplastic syndromes. The company's pipeline also includes Fimepinostat, an oral dual inhibitor of HDAC and PI3K enzymes for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma; CA-170, an oral, small molecule antagonist designated as CA-170 that selectively targets PD-L1 and VISTA; and CA-327, an oral, small molecule, TIM3/PD-L1, which is a molecule antagonist of PD-L1 and TIM3. It has collaboration agreement with Genentech Inc., or Genentech and F. Hoffmann-La Roche Ltd, or Roche, for the commercialization of Erivedge, an orally-administered small molecule hedgehog signaling pathway antagonist for the treatment of advanced basal cell carcinoma, or BCC; Aurigene Discovery Technologies Limited for the discovery, development, and commercialization of small molecule compounds in the areas of immuno-oncology and precision oncology; and also licensed four programs under the Aurigene collaboration, including emavusertib. Curis, Inc. was incorporated in 2000 and is headquartered in Lexington, Massachusetts.
Date |
For |
Estimate |
Reported |
Surprise |
surprise % |
2024-05-07 |
2024-03 |
-1.94 |
-2.05 |
-0.11 |
-5.67% |
2024-02-08 |
2023-12 |
-1.91 |
-2.03 |
-0.12 |
-6.28% |
2023-11-02 |
2023-09 |
-2.32 |
-2.13 |
0.19 |
8.19% |
2023-08-03 |
2023-06 |
-2.4 |
-2.4 |
N/A |
N/A |
2023-05-04 |
2023-03 |
-2.2 |
-2.4 |
-0.2 |
-9.09% |
2023-03-13 |
2022-12 |
-2.8 |
-2.4 |
0.4 |
14.29% |
Date |
Name |
Relation |
Quantity |
Description |
2016-09-06 |
AURIGENE DISCOVERY TECHNOLOGIES LTD |
Beneficial Owner of more than 10% of a Class of Security |
0.00 |
Purchase |
2022-01-30 |
DENTZER JAMES E |
Chief Executive Officer |
64.88K |
Sale |
2018-01-21 |
FATTAEY ALI |
Chief Executive Officer |
322.14K |
Stock Award(Grant) |
2019-01-22 |
GREENACRE MARTYN D |
Director |
26.09K |
Sale |
2019-01-22 |
KAITIN KENNETH I |
Director |
28.12K |
Sale |
2019-01-22 |
KUNKEL LORI ANNE |
Director |
22.20K |
Sale |
Institution Ownership
...
Report Date |
Organization |
Position |
Value |
Percentage |
2023-06-29 |
M28 Capital Management LP |
300.00K |
4.98M |
0.25% |
2023-06-29 |
Maverick Capital Ltd. |
277.05K |
4.60M |
0.24% |
2023-06-29 |
Vanguard Group Inc |
169.75K |
2.82M |
0.14% |
2023-06-29 |
Kingdon Capital Management LLC |
126.22K |
2.10M |
0.11% |
2023-06-29 |
Citigroup Inc. |
91.87K |
1.53M |
0.08% |
2023-06-29 |
Renaissance Technologies, LLC |
84.06K |
1.40M |
0.07% |
Report Date |
Organization |
Position |
Value |
Percentage |
2023-06-29 |
Vanguard Total Stock Market Index Fund |
109.15K |
1.81M |
0.09% |
2023-06-29 |
Vanguard Extended Market Index Fund |
52.70K |
874.84K |
0.04% |
2023-05-30 |
Fidelity Extended Market Index Fund |
20.63K |
320.68K |
0.02% |
2023-05-30 |
Fidelity Total Market Index Fund |
6.51K |
101.10K |
0.01% |
2023-06-29 |
Bridgeway Funds Inc-Ultra Small Company Market Fund |
12.00K |
199.20K |
0.01% |
Split |
Date |
1 : 20 |
2023-09-29 |
1 : 5 |
2018-05-30 |